Understanding the mechanisms of regulation of brain function by fat-soluble nutrient factors and application of these mechanisms for the improvement of brain function and treatment for brain diseases

• Project/Area Number: 20380078
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Food science
• Research Institution: Tokyo University of Agriculture
• Principal Investigator: KIDA Satoshi Tokyo University of Agriculture, 応用生物科学部, 教授 (80301547)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 学習・記憶 / ビタミンA / 不飽和脂肪酸 / トランスジェニックマウス / 脳機能障害 / レチノイン酸 / 情動行動 / 長期増強(LTP) / カナビノイド / 恐怖記憶 / 記憶不安定化 / トランスジュニックマウス / 認知症 / トレーニング

Research Abstract

Understanding roles of nutrient factors in brain function and mechanisms of the regulation of brain function by nutrient factors is important to develop the treatment for brain diseases. To do this, we have investigated roles of fat soluble-nutrient factors (Vitamin A (Retinoic Acid) and cannabinoids) in brain function.
Retinoic acid receptors (RARs) ubiquitously and highly express in brain. Previous studies have shown that RA-deficient mice and RARs knock out mice exhibit impairments of both hippocampal LTP and spatial memory, suggesting an essential role of RARs in learning and memory. To clarify the roles of RARs in learning and memory, we generated conditional mutant mice that enable to regulate forebrain-specific overexpression of RAR-alpha or dominant negative mutant (dn) of RAR-alpha using tetracycline system. We showed that dnRAR mice display impairments of AMPA receptor-mediated excitatory postsynaptic potentials and LTP in the hippocampus and hippocampus-dependent memory forma tion in a dnRAR expression-dependent manner. These observations suggest that RARs play important roles in hippocampus-dependent learning/memory and hippocampal LTP. Interestingly, we also found that dnRAR mice display down-regulation of PSD-95 and AMPA receptor subunit GluR1, but not NMDA receptor subunit NR1, in the hippocampus in a dnRAR expression-dependent manner. Therefore, we suggest that down-regulations of PSD-95 and GluR1 lead to impairments of hippocampus-dependent learning/memory and hippocampal LTP in dnRAR mice.
There is growing evidence that the reactivated long-term memory is de-stabilized and then re-stabilized through a gene expression dependent reconsolidation process. However, little is known about molecular mechanisms underlying destabilization of retrieved memory. Therefore, we examined roles of cannabinoid receptor CB1 in the destabilization of reactivated spatial and fear memory using Morris water maze and contextual fear conditioning tests. Infusion of an antagonist of CB1 receptor (SR141716A) together with anisomycin into hippocampus immediately after memory retrieval prevented the disruption of reactivated memory by protein synthesis inhibition. These results suggest that reactivated memory is destabilized through activation of hippocampal CB1 receptor.
From these studies, we suggest that vitamin A and endogenous cannabinoid are important to maintain and improve brain functions such as learning and memory. We are now examining effects of these fat-soluble factors on brain diseases using mouse model of brain diseases such as PTSD, memory deficits and anxiety.

Research Products

• [Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1. (2011)
  • Author(s): Uchida S., Hara K., Kobayashi A., Fujimoto M., Otsuki K., Yamagata H, Hobara T., Abe N., Higuchi F., Shibata T., Hasegawa S., Kida S, Nakai A., Watanabe Y.
  • Journal Title: Proc.Natl.Acad.Sci.U.S.A. 108
• [Journal Article] Induction and requirement of gene expression in the anterior cingulate cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory. (2011)
  • Author(s): Zhang Y., Fukushima H., Kida S
  • Journal Title: Mol.Brain. 4
• [Journal Article] Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze. (2011)
  • Author(s): Kim R., Moki R., Kida S
  • Journal Title: Mol.Brain. 4
• [Journal Article] mpaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1. (2011)
  • Author(s): Uchida, S., Hara, K., Kobayashi, A., Fujimoto, M., Otsuki, K., Yamagata, H,, Hobara, T., Abe, N., Higuchi, F., Shibata T., Hasegawa, S., Kida, S., Nakai, A., Watanabe, Y.
  • Journal Title: Proc.Natl.Acad.Sci.U.S.A. Volume: 108 Pages: 1681-6
  • Peer Reviewed
• [Journal Article] Induction and requirement of gene expression in the anterior cingulate cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory. (2011)
  • Author(s): Zhang, Y., Fukushima, H., Kida, S
  • Journal Title: Molecular Brain Volume: 4 Pages: 4-4
  • Peer Reviewed
• [Journal Article] Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze. (2011)
  • Author(s): Kim, R., Moki, R., Kida, S
  • Journal Title: Molecular Brain Volume: 4 Pages: 9-9
  • Peer Reviewed
• [Journal Article] Development of tightly regulated tetracycline-dependent transcriptional activator and repressor co-expression system for the strong induction of transgene expression. (2011)
  • Author(s): Hosoda, H., Miyao, T., Uchida, S., Sakai, S., S., Kida, S
  • Journal Title: Cytotechnology. Volume: 63 Pages: 211-6
  • Peer Reviewed
• [Journal Article] Up-regulation of CREB-mediated transcription enhances both short- and long-term memory. (2011)
  • Author(s): Suzuki, A., Fukushima, H., Takuya Mukawa, T., Toyoda, H., Wu, L-J., Zhao, M-G., Hui Xu, H., Shang, Y., Endoh, K., Iwamoto, Mamiya, N., Okano, E., Hasegawa, H., Mercaldo, V., Yue Zhang, Y., Maeda, R., Ohta, M., Josselyn, S.A., Zhuo, M., Kida, S.
  • Journal Title: J.Neurosci. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Activin plays a key role in the maintenance of long-term memory and late-LTP. (2010)
  • Author(s): Ageta H., Ikegami S., Miura M., Masuda M., Migishima R., Hino T., Takashima N., Murayama A., Sugino H., Setou M., Kida S, Yokoyama M., Hasegawa Y., Tsuchida K., Aosaki T., Inokuchi K.
  • Journal Title: Learning and Memory 17
• [Journal Article] Calcium/calmodulin-dependent kinase IV contributes to translation-dependent early synaptic potentiation in the anterior cingulate cortex of adult mice. (2010)
  • Author(s): Toyoda H., Zhao M.G., Mercaldo V., Chen T., Descalzi G., Kida S, Zhuo M.
  • Journal Title: Mol.Brain. 3
• [Journal Article] CaMKIV over-expression boosts cortical 4-7 Hz oscillations during learning and 1-4 Hz delta oscillations during sleep. (2010)
  • Author(s): Steenland H.W., Wu V., Fukushima H., Kida S, Zhuo M.
  • Journal Title: Mol.Brain. 3
• [Journal Article] Activin plays a key role in the maintenance of long-term memory and late-LTP. (2010)
  • Author(s): Ageta H., Ikegami S., Miura M., Masuda M., Migishima R., Hino T., Takashima N., Murayama A., Sugino H., Setou M., Kida, S., Yokoyama M., Hasegawa Y, Tsuchida K., Aosaki T., Inokuchi K.
  • Journal Title: Learning and Memory Volume: 17 Pages: 176-185
  • Peer Reviewed
• [Journal Article] CaMKIV over-expression boosts cortical 4-7 Hz oscillations during Learning and 1-4 Hz delta oscillations during sleep. (2010)
  • Author(s): Steenland, H.W., Wu, V., Fukushima, H., Kida, S., Zhuo, M.
  • Journal Title: Molecular Brain Volume: 3 Pages: 16-16
  • Peer Reviewed
• [Journal Article] Calcium/calmodulin-dependent kinase IV contributes to translation-dependent early synaptic potentiation in the anterior cingulate cortex of adult mice. (2010)
  • Author(s): Toyoda, H., Zhao, M.G., Mercaldo, V., Chen, T., Descalzi, G., Kida, S., Zhuo, M.
  • Journal Title: Molecular Brain Volume: 3 Pages: 27-27
  • Peer Reviewed
• [Journal Article] Activin plays a key role in the maintenance of long-term memory and late-LTP (2010)
  • Author(s): Ageta H, Ikegami S, Miura M, Masuda M, Migishima R, Hino T, Takashima N, Murayama A, Sugino H, Setou M, Kida S, Yokoyama M, Hasegawa Y, Tsuchida K, Aosaki T, Inokuchi K
  • Journal Title: Learning & Memory 17 Pages: 176-85
  • Peer Reviewed
• [Journal Article] 恐怖記憶制御機構 (2009)
  • Author(s): 喜田聡
  • Journal Title: 分子精神医学 9 Pages: 364-366
• [Journal Article] Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory. (2009)
  • Author(s): Mamiya N, Fukushima H, Suzuki A, Matsuyama Z, Homma S, Frankland PW, Kida S
  • Journal Title: The Journal of neuroscience 29 Pages: 402-13
• [Journal Article] Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression. (2009)
  • Author(s): Hasegawa S, Furuichi T, Yoshida T, Endoh K, Kato K, Sado M, Maeda R, Kitamoto A, Miyao T, Suzuki R, Homma S, Masushige S, Kajii Y, Kida S
  • Journal Title: Molecular brain 2 Pages: 6-6
• [Journal Article] Ca2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex. (2009)
  • Author(s): Wang H, Fukushima H, Kida S, Zhuo M
  • Journal Title: The Journal of biological chemistry 284 Pages: 18953-62
• [Journal Article] Mechanisms of reconsolidation and extinction of fear memory. (2009)
  • Author(s): Kida S, Fukushima H, Mamiya N
  • Journal Title: Nihon shinkei seishin yakurigaku zasshi=Japanese journal of psychopharmacology 29 Pages: 125-33
  • NAID: 10025185902
• [Journal Article] Neuroreport (2009)
  • Author(s): Isosaka T, Kida S, Kohno T, Hattori K, Yuasa S, Hippocampal Fyn activity regulates extinction of contextual fear.
  • Journal Title: 20 Pages: 1461-5
• [Journal Article] CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription. (2009)
  • Author(s): Hosoda H, Kato K, Asano H, Ito M, Kato H, Iwamoto T, Suzuki A, Masushige S, Kida S
  • Journal Title: Molecular brain 2 Pages: 34-34
• [Journal Article] Ca2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex. (2009)
  • Author(s): Wang H, Fukushima H, Kida S, Zhuo M
  • Journal Title: The Journal of Biological Chemistry 284 Pages: 18953-62
  • Peer Reviewed
• [Journal Article] Hippocampal Fyn activity regulates extinction of contextual fear. (2009)
  • Author(s): Isosaka T, Kida S, Kohno T, Hattori K, Yuasa S
  • Journal Title: Neuroreport 20 Pages: 1461-5
  • Peer Reviewed
• [Journal Article] CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription. (2009)
  • Author(s): Hosoda H, Kato K, Asano H, Ito M, Kato H, Iwamoto T, Suzuki A, Masushige S, Kida S
  • Journal Title: Molecular Brain 2 Pages: 34-34
  • Peer Reviewed
• [Journal Article] Mechanisms of reconsolidation and extinction of fear memory (2009)
  • Author(s): Kida S, Fukushima H, Mamiya N
  • Journal Title: Nihon shinkei seishin yakurigaku zasshi=Japanese journal of psychopharmacology 29 Pages: 125-33
  • NAID: 10025185902
• [Journal Article] Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory. (2009)
  • Author(s): Mamiya, N., Fukushima, H., Suzuki, A., Matsuyama, Z., Homma, S., Frankland, P. W. & Kida. S.
  • Journal Title: J. Neurosci. 29 Pages: 402-13
  • Peer Reviewed
• [Journal Article] Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression. (2009)
  • Author(s): Hasegawa, H., Furuichi, T., Yoshida, Y., Endoh, K., Kato, K., Sado, M., Maeda, R., Kitamoto, A., Miyao, T., Suzuki, R., Homma, S., Masushige, S., Kajii, Y. & Kida, S.
  • Journal Title: Mol. Brain 2 Pages: 6-6
  • Peer Reviewed
• [Journal Article] Activin in the brain modulates anxiety-related behavior and adult neurogenesis. (2008)
  • Author(s): Ageta H, Murayama A, Migishima R, Kida S, Tsuchida K, Yokoyama M, Inokuchi K
  • Journal Title: PLoS ONE 3 e1869
• [Journal Article] Genetic enhancement of trace fear memory and cingulate potentiation in mice overexpressing Ca2+/calmodulin-dependent protein kinase IV. (2008)
  • Author(s): Wu LJ, Zhang XH, Fukushima H, Zhang F, Wang H, Toyoda H, Li BM, Kida S, Zhuo M
  • Journal Title: The European journal of neuroscience 27 Pages: 1923-32
• [Journal Article] Activation of LVGCCs and CB1 receptors required for destabilization of reactivated contextual fear memories. (2008)
  • Author(s): Suzuki A, Mukawa T, Tsukagoshi A, Frankland PW, Kida S
  • Journal Title: Learning&memory(Cold Spring Harbor, N.Y.) 15 Pages: 426-33
• [Journal Article] Activation of Fyn tyrosine kinase in the mouse dorsal hippocampus is essential for contextual fear conditioning. (2008)
  • Author(s): Isosaka T, Hattori K, Kida S, Kohno T, Nakazawa T, Yamamoto T, Yagi T, Yuasa S
  • Journal Title: The European journal of neuroscience 28 Pages: 973-81
• [Journal Article] Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging. (2008)
  • Author(s): Fukushima H, Maeda R, Suzuki R, Suzuki A, Nomoto M, Toyoda H, Wu LJ, Xu H, Zhao MG, Ueda K, Kitamoto A, Mamiya N, Yoshida T, Homma S, Masushige S, Zhuo M, Kida S
  • Journal Title: The Journal of neuroscience 28 Pages: 9910-9
• [Journal Article] Activin in the brain modulates anxiety-related behavior and adult neurogenesis. (2008)
  • Author(s): Ageta, H., Murayama, A., Migishima, R., Kida, S., Tsuchida, K., Yokoyama, M. & Inokuchi, K.
  • Journal Title: PLoS ONE 3
  • Peer Reviewed
• [Journal Article] Genetic Enhancement of Trace Fear Memory and Cingulate Potentiation in Mice Overexpressing Ca2+/Calmodulin-Dependent Protein Kinase IV. (2008)
  • Author(s): Wu, L. -J., Zhang, X-H., Fukushima, H., Zhang, F., Wang, H., Toyoda, T., Li, B. -M., Kida. S. & Zhuo, M.
  • Journal Title: Eur. J. Neurosci. 27 Pages: 1923-32
  • Peer Reviewed
• [Journal Article] Activation of LVGCCs and CB1 receptors required for destabilization of reactivated contextual fear memories. (2008)
  • Author(s): Suzuki, A., Mukawa, T., Tsukagoshi, A., Frankland, P. W. & Kida, S.
  • Journal Title: Learn. Mem. 15 Pages: 973-81
  • Peer Reviewed
• [Journal Article] Up-regulation of CaMKIV improves memory formation and rescues memory loss with aging. (2008)
  • Author(s): Fukushima, H., Maeda, R., Suzuki, R., Suzuki, A., Nomoto, M., Toyoda, H., Wu, L. -J., Xu, H., Zhao, M. -G., Ueda, K., Kitamoto, K., Mamiya, N., Yoshida, T., Homma, S., Masushige, S., Zhuo, M. & Kida, S.
  • Journal Title: J. Neurosci. 28 Pages: 9910-19
  • Peer Reviewed
• [Journal Article] Activation of Fyn tyrosine kinase in the mouse dorsal hippocampus is essential for contextual fear conditioning. (2008)
  • Author(s): Isosaka, T., Hattori, K., Kida, S., Kohno, T., Nakazawa, T., Yamamoto, T., Yagi, T. & Yuasa, S.
  • Journal Title: Eur. J. Neurosci. 28 Pages: 973-81
  • Peer Reviewed
• [Journal Article] Development of tightly regulated tetracycline-dependent transcriptional activator and repressor co-expression system for the strong induction of transgene expression.
  • Author(s): Hosoda H., Miyao T., Uchida S., Sakai S., S., Kida S
  • Journal Title: Cytotechnology. 63
• [Journal Article] Up-regulation of CREB-mediated transcription enhances both short- and long-term memory.
  • Author(s): Suzuki A., Fukushima H., Takuya Mukawa T., Toyoda H., Wu L-J., Zhao M-G., Hui Xu H., Shang Y., Endoh K., Iwamoto, Mamiya N., Okano E., Hasegawa H., Mercaldo V., Yue Zhang Y., Maeda R., Ohta M., Josselyn S.A., Zhuo M., Kida S
  • Journal Title: J.Neurosci. (in press)
• [Presentation] 恐怖条件付け文脈記憶再固定化と消去に対する扁桃体カルシニューリンの役割の解析 (2011)
  • Author(s): 金亮、Karim Nader、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
  • Year and Date: 2011-03-26
• [Presentation] NMDA型グルタミン酸受容体阻害剤メマンチン投与による成体海馬神経新生促進と海馬依存性学習・記憶形成能力の向上 (2011)
  • Author(s): 石川理絵、金亮、奥川哲央、難波隆志、高坂新一、内野茂夫、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
  • Year and Date: 2011-03-26
• [Presentation] レチノイン酸情報伝達系不活性化によるPSD-95とAMPA型グルタミン酸受容体GluRlサブユニットの発現抑制 (2011)
  • Author(s): 光田幸司、野本真順、武田陽平、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
  • Year and Date: 2011-03-26
• [Presentation] 海馬依存性学習・記憶形成に対するビタミンB1の役割の解析 (2011)
  • Author(s): 大石諭、永田幹、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
  • Year and Date: 2011-03-26
• [Presentation] Enhancement of fear memory after retrieval in passive avoidance task. (2011)
  • Author(s): 喜田聡
  • Organizer: 23^<rd> Winter Conference on Neural Plasticity
  • Place of Presentation: Tahiti
  • Year and Date: 2011-02-14
• [Presentation] Enhancement of fear memory after retrieval in passive avoidance task (2011)
  • Author(s): 喜田聡
  • Organizer: 23^<rd> Winter Conference on Neural Plasticity
  • Place of Presentation: Tahiti
  • Year and Date: 2011-02-14
• [Presentation] 前脳領域BMAL1による時間帯特異的な記憶想起制御 (2011)
  • Author(s): 長谷川俊介、太田美穂、齋藤香織、細田浩司、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 恐怖条件付け文脈記憶再固定化と消去に対する扁桃体カルシニューリンの役割の解析 (2011)
  • Author(s): 金亮、Karim Nader、喜田聡
  • Organizer: 第55回日本農芸化学大会
  • Place of Presentation: 京都
• [Presentation] NMDA型グルタミン酸受容体阻害剤メマンチン投与による成体海馬神経新生促進と海馬依存性学習-記憶形成能力の向上 (2011)
  • Author(s): 石川理絵、金亮、奥川哲央、難波隆志、高坂新一、内野茂夫、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] レチノイン酸情報伝達系不活性化によるPSD-95とAMPA型グルタミン酸受容体GluR1サブユニットの発現抑制 (2011)
  • Author(s): 光田幸司、野本真順、武田陽平、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 海馬依存性学習-記憶形成に対するビタミンB1の役割の解析 (2011)
  • Author(s): 大石諭、永田幹、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 社会的認知記憶形成を制御する脳領野の同定 (2011)
  • Author(s): 谷水俊之、門間和音、張悦、福島穂高、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 学習能力に対する転写因子CREBの役割 (2011)
  • Author(s): 芹田龍郎、福島穂高、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 情動行動制御に対するレチノイン酸情報伝達系の役割の解析 (2011)
  • Author(s): 齋藤香織、野本真順、武田陽平、光田幸司、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] Circadian Regulation of Memory Retrieval (2010)
  • Author(s): 喜田聡
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会ワークショップ「生物時計におけるbHLH転写因子の機能と制御」
  • Place of Presentation: 神戸
  • Year and Date: 2010-12-10
• [Presentation] Regulation of memory formation by Retinoic acid receptors (2010)
  • Author(s): Takeda Y, Nomoto M, Enomoto H, Choi T, Uchida S, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2010-12-10
• [Presentation] Up-regulation of CREB-mediated transcription enhances both short- and long-term memory. (2010)
  • Author(s): Fukushima, H., Mukawa, T., Suzuki, A., Okano, E., Endo, K., Kida, S.
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe
  • Year and Date: 2010-12-07
• [Presentation] Roles of calcineurin in reconsolidation, destabilization and extinction of contextual fear memory. (2010)
  • Author(s): Kim, R., Nader, K., Kida, S.
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe
  • Year and Date: 2010-12-07
• [Presentation] Brain regions activated following retrieval of recent and remote fear memory in passive avoidance task. (2010)
  • Author(s): Zhang, Y., Fukushima, H., Kida, S.
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe
  • Year and Date: 2010-12-07
• [Presentation] Regulation of memory formation by Retinoic acid receptors. (2010)
  • Author(s): Takeda, Y., Nomoto, M., Kida, S
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe
  • Year and Date: 2010-12-07
• [Presentation] CREB regulates memory performance though expression regulation of BDNF. (2010)
  • Author(s): Fukushima, H., Mukawa, T., Suzuki, A., Okano, E., Endo, K., Kida, S.
  • Organizer: 40th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: San Diego
  • Year and Date: 2010-11-13
• [Presentation] Roles of calcineurin in hippocampus and amygdala in reconsolidation and extinction of contextual fear memory. (2010)
  • Author(s): Kim, R., Nader, K., Kida, S.
  • Organizer: 40th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: San Diego
  • Year and Date: 2010-11-13
• [Presentation] 想起後の恐怖記憶増強のメカニズム (2010)
  • Author(s): 喜田聡
  • Organizer: 第11回八ヶ岳シンポジウム
  • Place of Presentation: 蓼科
  • Year and Date: 2010-09-26
• [Presentation] Enhancement of fear memory after retrieval (2010)
  • Author(s): 喜田聡
  • Organizer: 3^<rd> Brain Plasticity Symposium, Queenland Brain Institute
  • Place of Presentation: Brisbane
  • Year and Date: 2010-09-14
• [Presentation] Enhancement of fear memory after retrieval. (2010)
  • Author(s): 喜田聡
  • Organizer: 日本神経科学会大会Neuro2010シンポジウム "負情動の生物学的基盤"
  • Place of Presentation: 神戸
  • Year and Date: 2010-09-03
• [Presentation] Enhancement of fear memory after retrieval. (2010)
  • Author(s): 喜田聡
  • Organizer: 日本神経科学会大会Neuro2010シンポジウム"負情動の生物学的基盤"
  • Place of Presentation: 神戸
  • Year and Date: 2010-09-03
• [Presentation] 転写因子CREBとBDNFによる協同的記憶制御. (2010)
  • Author(s): 福島穂高、夢川琢也、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
  • Year and Date: 2010-09-02
• [Presentation] 脳栄養学・精神栄養学の重要性-脳科学と食品科学・栄養学との接点- (2010)
  • Author(s): 喜田聡
  • Organizer: 日本食品科学工学会
  • Place of Presentation: 東京(特別講演)
  • Year and Date: 2010-09-01
• [Presentation] 脳栄養学・精神栄養学の重要性-脳科学と食品科学・栄養学との接点- (2010)
  • Author(s): 喜田聡
  • Organizer: 日本食品科学工学会第57回大会 特別講演
  • Place of Presentation: 東京
  • Year and Date: 2010-09-01
• [Presentation] 前脳領域BMAL1による記憶想起のサーカディアン制御 (2010)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 「包括脳ネットワーク」夏のワークショップ
  • Place of Presentation: 札幌
  • Year and Date: 2010-07-27
• [Presentation] Enhancement of fear memory after retrieval (2010)
  • Author(s): 喜田聡
  • Organizer: International Conference for Neurons and Brain Disease
  • Place of Presentation: Bristol
  • Year and Date: 2010-07-01
• [Presentation] ビタミンA情報伝達経路による学習・記憶能力制御 (2010)
  • Author(s): 喜田聡
  • Organizer: 日本栄養・食糧学会シンポジウム 脳栄養学・精神栄養学の最前線
  • Place of Presentation: 徳島
  • Year and Date: 2010-05-23
• [Presentation] 受動回避記憶再固定化・強化に関わる前脳領域の活性制御機構の解析 (2010)
  • Author(s): 福島穂高, 張悦, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] FRETを利用した培養ニューロンにおけるαCaMKII活性調節機構の解析 (2010)
  • Author(s): 加藤健一, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] 想起後の恐怖記憶安定性制御に対する海馬脱リン酸化酵素群の役割の解析 (2010)
  • Author(s): 金亮, Nader K, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] 細胞・個体レベルのサーカディアン制御に対する前脳領域BMAL 1の役割の解析 (2010)
  • Author(s): 太田美穂, 長谷川俊介, 細田浩司, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] 受動的回避反応課題を用いた古い恐怖記憶制御に関与する脳領域の同定 (2010)
  • Author(s): 張悦, 福島穂高, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] 前脳領域BMAL1による記憶想起のサーカディアン制御 (2010)
  • Author(s): 長谷川俊介, 太田美穂, 細田浩司, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] レチノイン酸受容体情報伝達経路による海馬神経可塑性の制御 (2010)
  • Author(s): 野本真順, 武田陽平, 榎本初音, 崔泰樹, 内田周作, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路による記憶形成の制御 (2010)
  • Author(s): 武田陽平, 野本真順, 榎本初音, 内田周作, 喜田聡
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-28
• [Presentation] Visualization and monitoring of αCaMKII activation in cortical neurons using FRET. (2010)
  • Author(s): Kennichi Kato ; Taku Iwamoto, Satoshi Kida
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] Mechanisms of enhancement and destabilization of fear memory following the retrieval in passive avoidance task. (2010)
  • Author(s): Hotaka FUKUSHIMA, Akinobu SUZUKI, Satoshi KIDA
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] Retinoic acid receptors function as positive regulators for memory formation. (2010)
  • Author(s): Masanori NOMOTO, Hatsune ENOMOTO, Tesu CHOI, Shusaku UCHIDA, Takahisa MIYAO, Satoshi KIDA
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] Analysis of brain regions associated with fear memory extinction using passive avoidance task (2010)
  • Author(s): Yue Zhang, Hotaka Fukushima, Satoshi Kida
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] Down-regulation of hippocampal activity is important for the interaction between reconsolidation and extinction of contextual fear. (2010)
  • Author(s): Yuya KANO, Nori MAMIYA, Akinobu SUZUKI、Satoshi KIDA
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] Roles of transcription factor BMAL1 in circadian rhythm using conditional mutant mice. (2010)
  • Author(s): Miho OHTA, Shunsuke HASEGAWA, Hiroshi HOSODA, Satoshi KIDA
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] CLOCK/BMAL1 signaling pathway in forebrain contributes circadian regulation of memory formation. (2010)
  • Author(s): Shunsuke HASEGAWA, Miho OHTA, Hiroshi HOSODA, Satoshi KIDA
  • Organizer: 日本神経科学会大会Neuro2010
  • Place of Presentation: 名古屋
• [Presentation] BMAL1による記憶プロセスのサーカディアン制御 (2010)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路による海馬神経可塑性の制御 (2010)
  • Author(s): 野本真順、武田陽平、榎本初音、崔泰樹、内田周作、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] コンディショナル変異マウスを用いた情動行動とサーカディアンリズムに対する転写調節因子BMAL1の役割の解析 (2010)
  • Author(s): 太田美穂、長谷川俊介、細田浩司、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] 受動回避記憶再固定化・強化及び不安定化機構に対する前脳領域の役割の解析 (2010)
  • Author(s): 福島穂高、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] 恐怖記憶想起後の安定性制御に対する海馬脱リン酸化酵素群の役割の解析 (2010)
  • Author(s): 金亮、KARIM NADER,喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] 受動的回避反応課題を用いた恐怖記憶消去を制御する脳領域の解析 (2010)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路による記憶形成の制御 (2010)
  • Author(s): 武田陽平、野本真順、榎本初音、崔泰樹、内田周作、宮尾貴久、喜田聡
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] レチノイン酸受容体情報伝達経路による海馬神経可塑性の制御 (2010)
  • Author(s): 野本真順、武田陽平、榎本初音、崔泰樹、内田周作、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 前脳領域BMAL1による記憶想起のサーカディアン制御 (2010)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 受動的回避反応課題を用いた古い恐怖記憶制御に関与する脳領域の同定 (2010)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 細胞・個体レベルのサーカディアン制御に対する前脳領域BMAL1の役割の解析 (2010)
  • Author(s): 太田美穂、長谷川俊介、細田浩司、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 想起後の恐怖記憶安定性制御に対する海馬脱リン酸化酵素群の役割の解析 (2010)
  • Author(s): 金亮、Karim NADER、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] FRETを利用した培養ニューロンにおけるαCaMKII活性調節機構の解析 (2010)
  • Author(s): 加藤健一、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 受動回避記憶再固定化・強化に関わる前脳領域の活性制御機構の解析 (2010)
  • Author(s): 福島穂高、張悦、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路による記憶形成の制御 (2010)
  • Author(s): 武田陽平、野本真順、榎本初音、内田周作、喜田聡
  • Organizer: 日本農芸化学会
  • Place of Presentation: 東京
• [Presentation] BMAL1による記憶想起のサーカディアン制御 (2010)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] 転写因子CREBとBDNFによる協同的記憶制御 (2010)
  • Author(s): 福島穂高、夢川琢也、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] 恐怖記憶再固定化と消去に対するカルシニューリンの役割の解析 (2010)
  • Author(s): 金亮、Karim Nader、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] 受動的回避反応課題を用いた古い恐怖記憶想起後に活性化される脳領域の同定 (2010)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] レチノイン酸受容体による記憶形成と神経可塑性制御の分子機構 (2010)
  • Author(s): 野本真順、武田陽平、光田幸司、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路による記憶形成の制御 (2010)
  • Author(s): 武田陽平、野本真順、榎本初音、崔泰樹、内田周作、宮尾貴久、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] 社会的認知記憶固定化分子機構の組織学的解析 (2010)
  • Author(s): 谷水俊之、門間和音、張悦、福島穂高、喜田聡
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸
• [Presentation] レチノイン酸受容体情報伝達経路による海馬神経可塑性の制御 (2010)
  • Author(s): 野本真順、武田陽平、光田幸司、榎本初音、崔泰樹、内田周作、喜田聡
  • Organizer: 日本分子生物学会第10回春季シンポジウム
  • Place of Presentation: 松島
• [Presentation] レチノイン酸受容体による記憶形成と神経可塑性制御の分子機構 (2010)
  • Author(s): 光田幸司、武田陽平、野本真順、榎本初音、内田周作、喜田聡
  • Organizer: 日本分子生物学会第10回春季シンポジウム
  • Place of Presentation: 松島
• [Presentation] 脳機能に対する前脳領域のサーカディアン転写リズムの役割 (2010)
  • Author(s): 齋藤香織、太田美穂、長谷川俊介、細田浩司、喜田聡
  • Organizer: 日本分子生物学会第10回春季シンポジウム
  • Place of Presentation: 松島
• [Presentation] 前脳領域BMAL1による記憶想起のサーカディアン制御 (2010)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 平成22年度「包括脳ネットワーク」夏のワークショップ
  • Place of Presentation: 札幌
• [Presentation] CREB regulates memory performance though expression regulation of BDNF. (2010)
  • Author(s): Fukushima H., Mukawa T., Suzuki A., Okano E., Endo K., Kida, S.
  • Organizer: 40th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: San Diego.
• [Presentation] Roles of calcineurin in hippocampus and amygdala in reconsolidation and extinction of contextual fear memory. (2010)
  • Author(s): Kim R., Nader K., Kida, S
  • Organizer: 40th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: San Diego.
• [Presentation] BMAL1 plays a role in the circadian regulation of memory retrieval. (2010)
  • Author(s): Hasegawa S., Ohta M., Saito K., Hosoda H., Kida, S
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe
• [Presentation] Roles of calcineurin in reconsolidation, destabilization and extinction of contextual fear memory. (2010)
  • Author(s): Kim R., Nader K., Kida, S
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe.
• [Presentation] Brain regions activated following retrieval of recent and remote fear memory in passive avoidance task. (2010)
  • Author(s): Zhang Y., Fukushima H., Kida, S
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan
  • Place of Presentation: Kobe.
• [Presentation] Regulation of memory formation by Retinoic acid receptors. (2010)
  • Author(s): Takeda Y., Nomoto M., Kida, S
  • Organizer: 33th Annual Meeting of the Molecular Biology Society of Japan.
  • Place of Presentation: Kobe.
• [Presentation] 転写因子CREBと神経栄養因子BDNFによる協調作用による記憶能力の向上 (2010)
  • Author(s): 福島穂高、夢川琢也、鈴木章円、遠藤健吾、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] 受動的回避記憶を制御する脳領域の同定とその役割の解析 (2010)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 第55回日本農芸化学会大会
  • Place of Presentation: 京都
• [Presentation] Circadian memory regulation by BMAL1 (2009)
  • Author(s): Hasegawa S, Ohta M, Hosoda H, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-12
• [Presentation] Analysis of roles of protein phosphatases in hippocampus in regulation of reactivated contextual fear memory (2009)
  • Author(s): Kim R, Nader K, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-10
• [Presentation] Mechanisms for enhancement and reconsolidation of reactivated fear memory in passive avoidance task (2009)
  • Author(s): Fukushima H, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-10
• [Presentation] Analysis of roles of transcription factor BMAL1 in forebrain in emotional behaviors and circadian rhythms using conditional mutant mice (2009)
  • Author(s): Ohta M, Hasegawa S, Hosoda H, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-10
• [Presentation] Analysis of brain regions associating with fear memory extinction in passive avoidance task (2009)
  • Author(s): Zhang Y, Fukushima, H, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-10
• [Presentation] Roles of Retinoic Acid Receptors in hippocampal synaptic plasticity (2009)
  • Author(s): Nomoto M, Takeda Y, Enomoto H, Choi T, Uchida S, Kida S
  • Organizer: 日本分子生物学会(第32回)
  • Place of Presentation: 横浜
  • Year and Date: 2009-12-09
• [Presentation] Retinoic Acid Receptors positively regulate memory formation and LTP (2009)
  • Author(s): Nomoto M, Enomoto H, Takeda Y, Choi T, Uchida S, Kida S
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-21
• [Presentation] Mechanisms of enhancement and reconsolidation of reactivated fear memory in passive avoidance task (2009)
  • Author(s): Fukushima H, Zhang Y, Kida S
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-21
• [Presentation] Roles of transcription factor BMAL1 in circadian regulation of memory performance (2009)
  • Author(s): Hasegawa S, Ohta M, Hosoda H, Kida S
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-21
• [Presentation] Roles of transcription factor BMAL1 in circadian regulation of memory performance (2009)
  • Author(s): Hasegawa S, Ohta M, Hosoda H, Kida S
  • Organizer: Molecular Cellular Cognition Society
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-16
• [Presentation] Mechanisms of enhancement and reconsolidation of reactivated fear memory in passive avoidance task (2009)
  • Author(s): Fukushima H, Zhang Y, Kida S
  • Organizer: Molecular Cellular Cognition Society
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-16
• [Presentation] Retinoic Acid Receptors positively regulate memory formation and LTP (2009)
  • Author(s): Nomoto M, Enomoto H, Takeda Y, Choi T, Uchida S, Kida S
  • Organizer: Molecular Cellular Cognition Society
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-16
• [Presentation] NMDA型グルタミン酸受容体による恐怖記憶再固定化と消去の制御 (2009)
  • Author(s): 喜田聡
  • Organizer: 日本アミノ酸学会第3回学術大会(JSAAS 2009)
  • Place of Presentation: 京都
  • Year and Date: 2009-09-29
• [Presentation] NMDA型グルタミン酸受容体による恐怖記憶再固定化と消去の制御 (2009)
  • Author(s): 喜田聡
  • Organizer: 日本アミノ酸学会第3回学術大会
  • Place of Presentation: 京都
  • Year and Date: 2009-09-29
• [Presentation] Roles of transcription factor CREB in short and long-term memory formation. (2009)
  • Author(s): 喜田聡
  • Organizer: 日本神経科学会大会シンポジウム"The next generation of study on memory regulation ; from phenomenology to molecular mechanisms"
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Roles of transcription factor CREB in short and long-term memory formation (2009)
  • Author(s): Kida S
  • Organizer: 日本神経科学会(シンポジウム招待講演)
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Roles of transcription factor BMAL1 in forebrain in emotional behaviors and circadian rhythm (2009)
  • Author(s): Ohta M, Hasegawa S, Hosoda H, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] CLOCK/BMAL1 signaling pathway in forebrain contributes to circadian regulation of memory formation (2009)
  • Author(s): Hasegawa S, Ohta M, Hosoda H, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Regulation of glutamate receptors in hippocampus following retrieval of contextual fear memory (2009)
  • Author(s): Kano Y, Mamiya N, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Analysis of brain regions regulating extinction of fear memory using passive avoidance task (2009)
  • Author(s): Zhang Y, Fukushima, H, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Positive and negative regulation of memory formation by Retinoic acid receptors (2009)
  • Author(s): Nomoto M, Enomoto H, Takeda Y, Choi T, Uchida S, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Mechanisms of destabilization and restabilization of fear memory following the retrieval in passive avoidance task (2009)
  • Author(s): Fukushima H, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-18
• [Presentation] Roles of transcription factor BMAL1 in forebrain in emotional behaviors and circadian rhythm (2009)
  • Author(s): Ohta M, Hasegawa S, Hosoda H, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] CLOCK/BMAL1 signaling pathway in forebrain contributes to circadian regulation of memory formation (2009)
  • Author(s): Hasegawa S, Ohta M, Hosoda H, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] Brain Region-Specific Gene Expression Activation Required for Reconsolidation and Extinction of Contextual Fear Memory (2009)
  • Author(s): Mamiya, N, Fukushima, H, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] Positive and negative regulation of memory formation by Retinoic acid receptors (2009)
  • Author(s): Nomoto M, Enomoto H, Takeda Y, Choi T, Uchida S, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] Mechanisms of destabilization and restabilization of fear memory following the retrieval in passive avoidance task (2009)
  • Author(s): Fukushima H, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] Analysis of brain regions regulating extinction of fear memory using passive avoidance task (2009)
  • Author(s): Zhang Y, Fukushima, H, Kida S
  • Organizer: The 4th Molecular Cellular Cognition Society -Asia Symposium
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-15
• [Presentation] Regulation of alpha CaMKII-activation in living cells (2009)
  • Author(s): Kato K, Kida S
  • Organizer: 日本神経科学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-15
• [Presentation] Roles of CREB in formation of short-term memory (2009)
  • Author(s): 喜田聡
  • Organizer: International Conference for Neurons and Brain Disease
  • Place of Presentation: トロント大学
  • Year and Date: 2009-07-22
• [Presentation] Roles of CREB in formation of short-term memory (2009)
  • Author(s): Kida S
  • Organizer: International Conference for Neurons and Brain Disease(シンポジウム招待講演)
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2009-07-22
• [Presentation] 受動的回避反応課題における恐怖記憶形成及び強化を制御する脳領域の解析 (2009)
  • Author(s): 張悦, 福島穂高, 喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-09
• [Presentation] 受動的回避反応課題を用いた恐怖記憶再固定化・強化制御の分子機構の解析 (2009)
  • Author(s): 福島穂高, 鈴木章円, 喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-09
• [Presentation] 恐怖条件付け文脈記憶再固定化と消去の相互作用メカニズムの解析 (2009)
  • Author(s): 間宮則, 鈴木章円, 松山善宰, 喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-09
• [Presentation] Roles of CaMKIV Signaling Pathway in Memory Formation. (2009)
  • Author(s): 喜田聡
  • Organizer: 日本神経化学会大会シンポジウム"Novel insights into the roles of protein kinases in synaptic plasticity and memory"
  • Place of Presentation: 伊香保
  • Year and Date: 2009-06-23
• [Presentation] Roles of CaMKIV Signaling Pathway in Memory Formation (2009)
  • Author(s): Kida S
  • Organizer: 日本神経化学会(シンポジウム招待講演)
  • Place of Presentation: 伊香保
  • Year and Date: 2009-06-23
• [Presentation] レチノイン酸受容体群による記憶形成制御機構の解明 (2009)
  • Author(s): 喜田聡、野本真順、榎本初音、崔泰樹、内田周作、本間清一、舛重正一
  • Organizer: 日本栄養・食糧学会大会
  • Place of Presentation: 長崎
  • Year and Date: 2009-05-24
• [Presentation] レチノイン酸受容体群による記憶形成制御機構の解明 (2009)
  • Author(s): 喜田聡
  • Organizer: 日本栄養食糧学会大会
  • Place of Presentation: 長崎
  • Year and Date: 2009-05-24
• [Presentation] ROLES OF CREB SIGNALING PATHWAY IN REGULATION OF FEAR MEMORY (2009)
  • Author(s): 喜田聡
  • Organizer: 17th European Congress of Psychiatry
  • Place of Presentation: Lisbon
• [Presentation] 脳部位特異的遺伝子発現制御を介する恐怖記憶再固定化と消去の誘導制御 (2009)
  • Author(s): 間宮則、福島穂高、鈴木章円、松山善宰、喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] 前脳領域におけるCLOCK/BMAL1情報伝達系による記憶能力のサーカディアン制御 (2009)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、本間清一、喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] 加齢に伴うCaMKIV発現量低下の阻止は記憶能力減退を防ぐ-CaMKIVは加齢による記憶力減退を防ぐ鍵遺伝子である- (2009)
  • Author(s): 福島穂高,前田良太,鈴木良祐,遠藤健吾,野本真順,間宮則,喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] Pin1遺伝子欠損マウスでは加齢後も記憶能力が維持される (2009)
  • Author(s): 大野春香、鈴木章円、内田隆史、喜田聡
  • Organizer: 第53回農芸化学会
  • Place of Presentation: 福岡
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路は記憶形成を正に制御する (2009)
  • Author(s): 野本真順、榎本初音、崔泰樹、内田周作、宮尾貴久、本間清一、喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] 受動的回避記憶の消去制御に関わる脳領域の解析 (2009)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] 短期記憶制御に対する転写調節因子CREBの役割 (2009)
  • Author(s): 夢川琢也、鈴木章円、岡野絵美子、遠藤健吾、喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] ROLES OF CREB SIGNALING PATHWAY IN REGULATION OF FEAR MEMORY (2009)
  • Author(s): 喜田 聡
  • Organizer: 17th European Congress of Psychiatryシンポジウム講演
  • Place of Presentation: Lisbon
• [Presentation] Pin1遺伝子欠損マウスでは加齢後も記憶能力が維持される (2009)
  • Author(s): 大野春香, 鈴木章円, 内田隆史, 喜田聡
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡
• [Presentation] Regulation of reactivated contextual fear memory : relationship between reconsolidation and extinction (2008)
  • Author(s): 喜田 聡
  • Organizer: 第31回日本神経科学大会シンポジウム講演
  • Place of Presentation: 東京国際フォーラム.
  • Year and Date: 2008-07-11
• [Presentation] ビタミンA情報伝達経路による学習・記憶能力制御 (2008)
  • Author(s): 喜田聡
  • Organizer: 第55回日本栄養食糧学会中部支部大会
  • Place of Presentation: 愛知教育大学
  • Year and Date: 2008-07-05
• [Presentation] ビタミンA情報伝達経路による学習・記憶能力制御 (2008)
  • Author(s): 喜田 聡
  • Organizer: 第55回日本栄養食糧学会中部支部大会シンポジウム講演
  • Place of Presentation: 愛知教育大学
  • Year and Date: 2008-07-05
• [Presentation] 恐怖記憶制御とPTSD-動物PTSDモデルを利用した恐怖記憶制御機構の解明 (2008)
  • Author(s): 喜田聡
  • Organizer: 会議名"第27回躁うつ病の薬理・生化学的研究懇話会シンポジウム"
  • Place of Presentation: 箱根プリンスホテル
• [Presentation] Regulation of reactivated contextual fear memory : relationship between reconsolidation and extinction (2008)
  • Author(s): 喜田聡
  • Organizer: 第31回日本神経科学大会シンポジウム講演
  • Place of Presentation: 東京
• [Presentation] Distinct gene expression regulation in reconsolidation and extinction phases of contextual fear memory (2008)
  • Author(s): 喜田聡
  • Organizer: International Conference of Neurons and Brain Disease
  • Place of Presentation: Seoul
• [Presentation] 想起後の恐怖記憶制御のメカニズム (2008)
  • Author(s): 喜田聡
  • Organizer: 第18 回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会・合同年会シンポジウム講演
  • Place of Presentation: 東京
• [Presentation] Roles of hippocampus in fear memory stability after retrieval (2008)
  • Author(s): 喜田聡
  • Organizer: Annual meeting of Society for Neuroscience
  • Place of Presentation: Washington D.C., USA
• [Presentation] 空間記憶再固定化を制御する脳領域の解析 (2008)
  • Author(s): 吉田有理紗、金亮、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] 転写調節因子CREBによる短期記憶形成制御 (2008)
  • Author(s): 夢川琢也、鈴木章円、岡野絵美子、遠藤健吾、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] アルツハイマーモデルPin1遺伝子欠損マウスの行動学的解析 (2008)
  • Author(s): 大野春香、鈴木章円、内田隆史、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] 前脳領域レチノイン酸受容体は記憶形成を正に制御する (2008)
  • Author(s): 野本真順、榎本初音、崔泰樹、内田周作、宮尾貴久、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] 受動的回避反応課題における恐怖記憶形成及び強化を制御する脳領域の解析 (2008)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] 受動的回避反応課題を用いた恐怖記憶再固定化・強化制御の分子機構の解析 (2008)
  • Author(s): 福島穂高、鈴木章円、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] 恐怖条件付け文脈記憶再固定化と消去の相互作用メカニズムの解析 (2008)
  • Author(s): 間宮則、鈴木章円、松山善宰、喜田聡
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory (2008)
  • Author(s): Mamiya N., Fukushima H., Suzuki A., Matsuyama Z., Homma S., Frankland P.W., Kida S
  • Organizer: Molecular Cellular Cognition Society
  • Place of Presentation: Washington D.C..
• [Presentation] Molecular mechanisms underlying destabilization and restabilization of spatial memory after retrieval. (2008)
  • Author(s): Ryang Kim, Ryouichi Moki, Satoshi Kida
  • Organizer: 38th Annual Meeting of the Society for Neuroscience(Dep of Bioscience, Tokyo University of Agriculture)
  • Place of Presentation: Washington D.C.
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路は記憶形成を正に制御する (2008)
  • Author(s): 野本真順、榎本初音、崔泰樹、内田周作、宮尾貴久、喜田聡
  • Organizer: 第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 短期記憶制御に対する転写調節因子CREBの役割の解析 (2008)
  • Author(s): 夢川琢也、鈴木章円、岡野絵美子、遠藤健吾、Min Zhuo、喜田聡
  • Organizer: 第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 前脳領域におけるCLOCK/BMAL1情報伝達系の抑制は記憶形成を阻害する (2008)
  • Author(s): 長谷川俊介、太田美穂、細田浩司、喜田聡
  • Organizer: 第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] コンディショナル変異マウスを用いた前脳領域における転写調節因子BMAL1の役割の解析 (2008)
  • Author(s): 太田美穂、長谷川俊介、細田浩司、喜田聡
  • Organizer: 第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 恐怖記憶再固定化と消去の相互作用における海馬、扁桃体及び前頭前野の役割の解析 (2008)
  • Author(s): 間宮則、鈴木章円、松山善宰、喜田聡
  • Organizer: 第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 空間記憶想起後の記憶不安定化制御機構の解析 (2008)
  • Author(s): 金亮、吉田有理紗、喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 受動的回避反応課題を用いた恐怖記憶再固定化及び強化を制御する脳領域の解析 (2008)
  • Author(s): 張悦、福島穂高、喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 受動回避記憶再固定化・強化制御に対する前脳領域の役割の解析 (2008)
  • Author(s): 福島穂高、鈴木章円、喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 恐怖記憶制御とPTSD-動物PTSDモデルを利用した恐怖記憶制御機構の解明 (2008)
  • Author(s): 喜田 聡
  • Organizer: 第27回 噪うつ病の薬理・生化学的研究懇話会シンポジウム
  • Place of Presentation: 箱根プリンスホテル
• [Presentation] Distinct gene expression regulation in reconsolidation and extinction phases of Contextual fear memory (2008)
  • Author(s): 喜田 聡
  • Organizer: International Conference of Neurons and Brain Disease (シンポジウム講演)
  • Place of Presentation: Seoul
• [Presentation] 想起後の恐怖記憶制御のメカニズム (2008)
  • Author(s): 喜田 聡
  • Organizer: 第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会・合同年会シンポジウム
  • Place of Presentation: 東京
• [Presentation] Roles of hippocampus in fear memory stability after retrieval (2008)
  • Author(s): 喜田 聡
  • Organizer: Annual meeting of Society for Neuroscience (シンポジウム講演)
  • Place of Presentation: Washington D. C., USA
• [Presentation] Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory (2008)
  • Author(s): Mamiya, N., Fukushima, H., Suzuki, A., Matsuyama, Z., Homma, S., *Frankland, P. W. & Kida, S.
  • Organizer: Molecular Cellular Cognition Society
  • Place of Presentation: Washington D. C.
• [Presentation] Molecular mechanisms underlying destabilization and restabilization of spatial memory after retrieval. (2008)
  • Author(s): Ryang Kim, Ryouichi Moki, Satoshi Kida
  • Organizer: 38th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: Washington D. C.
• [Presentation] Analyses of interaction between reconsolidation and extinction of contextual fear memory (2008)
  • Author(s): Mamiya, N., Fukushima, H., Suzuki, A., Matsuyama, Z., Homma, S., Frankland, P. W. & Kida, S
  • Organizer: 38th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: Washington D. C.
• [Presentation] 前脳領域レチノイン酸受容体情報伝達経路は記憶形成を正に制御する (2008)
  • Author(s): 野本真順, 榎本初音, 崔泰樹, 内田周作, 宮尾貴久, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 短期記憶制御に対する転写調節因子CREBの役割の解析 (2008)
  • Author(s): 夢川琢也, 鈴木章円, 岡野絵美子, 遠藤健吾, Min Zhuo, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 前脳領域におけるCLOCK/BMAL1情報伝達系の抑制は記憶形成を阻害する (2008)
  • Author(s): 長谷川俊介, 太田美穂, 細田浩司, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 恐怖記憶再固定化と消去の相互作用における海馬、扁桃体及び前頭前野の役割の解析 (2008)
  • Author(s): 間宮則, 鈴木章円, 松山善宰, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] コンディショナル変異マウスを用いた前脳領域における転写調節因子BMAL1の役割の解析 (2008)
  • Author(s): 太田美穂, 長谷川俊介, 細田浩司, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] 空間記憶想起後の記憶不安定化制御機構の解析. (2008)
  • Author(s): 金亮, 吉田有理紗, 喜田聡
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会(BMB2008)
  • Place of Presentation: 神戸
• [Presentation] Analyses of interaction between reconsolidation and extinction of contextual fear memory. (2007)
  • Author(s): Nori MAMIYA, Akinobu SUZUKI, Zensai MATSUYAMA, Satoshi KIDA
  • Organizer: 38th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: Washington D.C.
• [Presentation] 想起後の恐怖記憶増強のメカニズム
  • Author(s): 喜田聡
  • Organizer: 平成22年度生理学研究所研究会「感覚刺激・薬物による快・不快情動生成機構とその破綻」
  • Place of Presentation: 岡崎
• [Patent(Industrial Property Rights)] 記憶能力の減退に対する披検化合物のスクリーニング方法 (2009)
  • Inventor(s): 喜田聡
  • Industrial Property Rights Holder: 東京農業大学
  • Acquisition Date: 2009-03-26