Characterization of molecular mechanisms of bovine fat accumulation by global gene expression analysis
| Project/Area Number |
20380149
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Shinshu University |
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Principal Investigator |
ROH Sanggun Shinshu University, 大学院・農学研究科, 准教授 (90322130)
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| Co-Investigator(Kenkyū-buntansha) |
GOTOH Takfumi 九州大学, 農学研究院, 准教授 (70294907)
CHIKUNI Koichi 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所・研究チーム, チーム長 (40355061)
HIRAMATSU Kohzi 信州大学, 農学部, 教授 (80238386)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2010: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2008: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Keywords | ウシ / 脂肪細胞 / 遺伝子解析 / Chemerin / Adipogenin / 脂肪組織 / 網羅的解析 |
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| Research Abstract |
This study was to investigate the molecular mechanism of fat accumulation and adipogenesis by DNA chip using adipose tissues from 10- and 24-month-old Japanese Black Cattle. Several candidate genes were separated and identified from global gene expression analysis. Adipogenin, chemerin and mPARM-1 genes were confirmed to relate to lipid metabolism and adipocyte differentiation in bovine adipocytes. These results suggested that several genes were involved with adipogenesis and fat accumulation in bovine.
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Report
(4 results)
Research Products
(38 results)
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[Journal Article] Comparison of feeding systems : feed cost, palatability and environmental impact among hay fattened beef, consistent grass-only fed beef and conventional marbled beef in Wagyu (Japanese Black cattle).2010
Author(s)
Sithyphone K., M.Yabe, H.Horita, K.Hayashi, F.Tomiko, Y.Shiotsuka, T.Etoh, F.Ebara, O.Samadmanivong, J.Wegner, T.Gotoh.
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Journal Title
Animal Science Journal. 82
Pages: 352-359
Related Report
Peer Reviewed
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[Presentation] Chemerin, highly expressed in adipose tissues, stimulates the glycerol release in bovine differentiated adipocytes in vitro.2009
Author(s)
Song, S.H., Fukui, K., Hamano, K., Sasaki, S., Roh, S.G., Katoh, K.
Organizer
Proceeding of XIth International Symposium on Ruminant Physiology
Place of Presentation
Clermont-Ferrand, French
Year and Date
2009-09-07
Related Report
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[Presentation] Cloning and expression of bovine chemerin and chemerin receptor.2008
Author(s)
Roh, S.G., Song, S.H., Fukui, K, Satoh, T., Katoh, K., Sasaki, S.
Organizer
6th International Congress on Farm Animal Endocrinology
Place of Presentation
The Hotel Roanoke & Conference Center, Roanoke, USA
Year and Date
2008-11-15
Related Report
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[Presentation] Chemerin, highly expressed in adipose tissues, stimulates the glycerol release in bovine differentiated adipocytes in vitro.2008
Author(s)
Song, S.H., Fukui, K., Hamano, K., Sasaki, S., Roh, S.G., Katoh, K.
Organizer
Proceeding of XIth International Symposium on Ruminant Physiology p.662-663
Place of Presentation
Clermont-Ferrand、France
Year and Date
2008-09-07
Related Report
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