The Creation of Next Feeding System in Cattle : Studies on Metabolic Imprinting during Early Growth Stage

• Project/Area Number: 20380150
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Zootechnical science/Grassland science
• Research Institution: Kyushu University
• Principal Investigator: GOTOH Takafumi Kyushu University, 大学院・農学研究院, 准教授 (70294907)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000); Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2008: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
• Keywords: ウシ / 飼養 / 代謝インプリンティング / 代謝インプリング

Research Abstract

In this study, we investigated how the metabolic imprinting during an early growth stage influences on constitution of Wagyu cattle by molecular-biologically, morphologically and physiologically investigating. In conclusion, it was clarified that the feeding at high energy level during the early growth stage, what is called, metabolic imprinting treatment, markedly influenced not only mRNA expressions of genes related to meat quantity and quality in skeletal muscles but also meat quantity and quality in Wagyu cattle.

Research Products

• [Journal Article] Cellular conditions for intramuscular fat deposition in Japanese Black and Holstein steers. (2011)
  • Author(s): Albrecht, E., T.Gotoh, F.Ebara, J.X.Xu, T.Viergutz, G Nuernberg, S.Maak, J.Wegner.
  • Journal Title: Meat Science 89 Pages: 13-20
  • Peer Reviewed
• [Journal Article] Comparison of feeding systems : feed cost, palatability and environmental impact among hay fattened beef, consistent grass-only fed beef and conventional marbled beef in Wagyu (Japanese Black cattle). (2011)
  • Author(s): Sithyphone, et al.
  • Journal Title: Animal Science Journal Volume: 82 Pages: 352-359
  • Peer Reviewed
• [Journal Article] Cellular conditions for intramuscular fat deposition in Japanese Black and Holstein steers. (2011)
  • Author(s): Albrecht, et al.
  • Journal Title: Meat Science Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Comparison of feeding systems : feed cost, palatability and environmental impact among hay fattened beef, consistent grass-only fed beef and conventional marbled beef in Wagyu (Japanese Black cattle). (2010)
  • Author(s): Sithyphone K., M.Yabe, H.Horita, K.Hayashi, F.Tomiko, Y.Shiotsuka, T.Etoh, F.Ebara, O.Samadmanivong, J.Wegner, T.Gotoh.
  • Journal Title: Animal Science Joumal 82 Pages: 352-359
  • Peer Reviewed
• [Journal Article] The influence of fattening by Eco-feed based on Okara on the growth,meat quality and histochemical properties of the longissimus tharacis muscle in Japanese Black cattle. (2010)
  • Author(s): Sithyphone K., K.Matsuda, Y.Shiotsuka, T.Etoh, F.Tomiko, T.Shiroshita, T.Sin, T.Gotoh.
  • Journal Title: J.Fax.Agr.Kyushu Univ. 55(2) Pages: 247-252
• [Journal Article] Intensified nursing dramarically accelerates growth performance and the size of the body frame in Japanese Black and Holsteincrossbredsteers. (2010)
  • Author(s): Inada S., F.Ebara, S.Asaoka, K.Asada, Y.Isozaki, A.Saito, T.Gotoh
  • Journal Title: J.Anim.Vet.Adv. 9(6) Pages: 1037-1047
  • Peer Reviewed
• [Journal Article] Intensive nursing and feeding during the early growth period altered intramuscular adipogenesis in crossbred steers (Japanese Black male×Holstein female). (2010)
  • Author(s): Ebara F., S.Inada, S.Asaoka, Y.Isozaki, A.Saito, T.Etoh, Y.Shiotsuka, T.Gotoh.
  • Journal Title: J.Anim.Vet.Adv. 9(6) Pages: 982-989
  • Peer Reviewed
• [Journal Article] Differencesin muscle and fat accretion in Japanese Black and European cattle. (2009)
  • Author(s): Gotoh T., E.Albrecht, F.Teuscher, K.Kawabata, K.Sakashita, H.Iwamoto, J.Wegner.
  • Journal Title: Meat Science 82 Pages: 300-308
  • Peer Reviewed
• [Journal Article] 放牧を軸とした国内草資源フル活用による新たな肉牛飼養システムの提案 (2008)
  • Author(s): 後藤貴文・衛藤哲次・塩塚雄二・林恵介・文田登美子
  • Journal Title: 日本草地学会報 54 Pages: 182-194
  • Peer Reviewed
• [Presentation] A Novel Feeding System in Cattle : the Strategy of Metabolic Imprinting. (2010)
  • Author(s): Gotoh T., T.Fumita, K.Hayashi, T.Etoh, Y.Shiotsuka, K.Matsuda, F.Ebara, K.Etoh, K.Saitoh, K.Sakuma, S.Kaneda, T.Abe, R.Fujino, H.Suzuk, H.Hasebe, J.Wegner.
  • Organizer: The proceeding of 7th International AFAS joint symposium between Korea and Japan, current status and perspectives of agriculture, forestry and animal sciences in 2010, 212-217
  • Place of Presentation: in Chuncheon, Korea.
  • Year and Date: 2010-11-11
• [Presentation] Effect of Nutrition during an Early Growth Period on Body Composition in Calves Cloned From a Sire Having a High Marbling Potential. (2010)
  • Author(s): Fujimura, et al.
  • Organizer: The 7^<th> International AFAS joint symposium between Korea and Japan, current status and perspectives of agriculture, forestry and animal sciences in 2010
  • Place of Presentation: チュンチョン、韓国
  • Year and Date: 2010-11-11
• [Presentation] A Novel Feeding System in Cattle : the Strategy of Metabolic Imprinting. (2010)
  • Author(s): Gotoh, et al.
  • Organizer: The 7^<th> International AFAS joint symposium between Korea and Japan, current status and perspectives of agriculture, forestry and animal sciences in 2010
  • Place of Presentation: チュンチョン、韓国
  • Year and Date: 2010-11-11
• [Presentation] 自給飼料を活用した新しい牛肉生産展開の可能性を探る (2010)
  • Author(s): 後藤貴文
  • Organizer: 平成22年度近畿中国四国農業試験研究推進会議、畜産草地推進部会、問題別研究会「和牛放牧の展開-多様な和牛肉生産にむけて-」
  • Place of Presentation: (独)農研機構 近畿中国四国農業研究センターにて
  • Year and Date: 2010-11-08
• [Presentation] The Creation of a Good Quality Production System to Produce Sage Beef in Japan : Metabolic Imprinting by Nutrition Manipulation and Utilization of domestic Grass Resources. (2010)
  • Author(s): Gotoh, et al.
  • Organizer: The 14^<th> AAAP (Asian-Australasian Association of Animal Production Societies) Animal Science Congress
  • Place of Presentation: ピンタン、台湾
  • Year and Date: 2010-08-24
• [Presentation] Long-term feeding diet based on rice FEED produced domestically affects meat quantity and quality of chicken. (2010)
  • Author(s): Matsuda, et al.
  • Organizer: The 56^<th> International Congress of Meat Science and Technology
  • Place of Presentation: チェジュ、韓国
  • Year and Date: 2010-08-17
• [Presentation] Fat Deposition in Japanese Black and Holstein Steers fed a high energy diet. (2010)
  • Author(s): Albrecht, et al.
  • Organizer: The 56^<th> International Congress of Meat Science and Technology
  • Place of Presentation: チェジュ、韓国
  • Year and Date: 2010-08-15
• [Presentation] Metabolic imprinting effect in beef production : Effects of nutrition manipulation during an early growth stage on the meat quantity in Wagyu (Japanese Black). (2010)
  • Author(s): Gotoh, et al.
  • Organizer: The International conference on developmental origins of health and disease "the power of programming"
  • Place of Presentation: ミュンヘン、ドイツ
  • Year and Date: 2010-05-07
• [Presentation] Metabolic imprinting effects in grass-fed Wagyu (Japanese Black) beef production. (2010)
  • Author(s): Gotoh, T.
  • Organizer: American Society of Nutrition, mini-symposium EB2010 Animal research models in lipid and protein nutrition and physiology.
  • Place of Presentation: アナハイム、アメリカ合衆国
  • Year and Date: 2010-04-24
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:牛肉生産に関与した因子群の粗飼料肥育終了時の動態解析 (2010)
  • Author(s): 後藤貴文, ら
  • Organizer: 第112回日本畜産学会
  • Place of Presentation: 東京都(明治大学)
  • Year and Date: 2010-03-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:黒毛和種?への強化哺乳が粗飼料肥育牛の枝肉成績に及ぼす影響 (2010)
  • Author(s): 齋藤邦彦、後藤貴文, ら
  • Organizer: 第112回日本畜産学会
  • Place of Presentation: 東京都(明治大学)
  • Year and Date: 2010-03-29
• [Presentation] Metabolic imprinting effects in grass-fed Wagyu (Japanese Black) beef producrion. (2010)
  • Author(s): 後藤貴文
  • Organizer: The proceedings of 5101- American Sociery of Nutrition, mini-symposium EB2010 Animal research models in lipid and protein nutrition and physiology. (Invited)
  • Place of Presentation: in Anaheim, USA.
• [Presentation] Metabolic imprinting effect in beef production : Effects of nutrition manipulation during an early growth stage on the meat quantity in Wagyu (Japanese Black). (2010)
  • Author(s): Gotoh T., K.Etoh, K.Saitoh, K.Sakuma, S.Kaneda, T.Abe, T.Etoh, Y.Shiotsuka, R.Fujino, K.Matsuda, H.Suzuki, H.Hasebe, F.Ebara, S.Tabata, J.Wegner.
  • Organizer: The proceeding of the International conference on developmental origins of health and disease "the power of programming"
  • Place of Presentation: in Munich, Germany.
• [Presentation] Fat Deposition in Japanese Black and Holstein Steers fed a high energy diet. (2010)
  • Author(s): Albrecht E.,, T.Gotoh, T.Viergutz, G.Nurnberg, J.Wegner
  • Organizer: The proceeding of the 56th International Congress of Meat Science and Technology, 81
  • Place of Presentation: in Jeju, Korea
• [Presentation] The Creation of a Good Quality Production System to Produce Sage Beef in Japan : Metabolic Imprinting by Nutrition Manipulation and Utilization of domestic Grass Resources. (2010)
  • Author(s): Gotoh T., T.Fumita, K.Hayashi, T.Etoh, Y.Shiotsuka, K.Matsuda, F.Ebara, J.Wegner.
  • Organizer: The proceeding of the 14th AAAP (Asian-Australasian Association of Animal Production Societies) Animal Science Congress 303-307
  • Place of Presentation: in Pingtung Taiwan.
• [Presentation] Metabolic imprinting effect in beef production : Influence of Nutrition manipulation during an early growth stage on carcass characteristics and intramuscular fat content of longissimus muscle in Wagyu (Japanese Black). (2010)
  • Author(s): Gotoh T., K.Etoh, K.Saitoh, K.Metoki, S.Kaneda, T.Abe, T.Etoh, Y.Shiotsuka, R.Fujino, K.Matsuda, H.Suzuki, H.Hasebe, F.Ebara, J.Wegner, S.Tabata.
  • Organizer: The proceeding of the 3rd EAAP (European Federation of Animal Science) International Syposium on Energy and Protein Metabolism and Nutrition (ISBN : 978-90-8686-153-8)
  • Place of Presentation: in Parma, Italy.
• [Presentation] Influence of intensive nursing and feeding during early growth stage on growth and muscle physiology in grass-fattening Japanese Black cattle (Wagyu). (2010)
  • Author(s): K.Etoh, K.Metoki, S.Kaneda,T.Abe, T.Etoh, K.Hayashi, Y.Nakamura, F.Ebara, J.Wegner, T.Gotoh
  • Organizer: Proceedings of the XIth International Symposium on Ruminant Physiology (Digestion, metabolism, and effects of nutrition on reproduction and welfare).
  • Place of Presentation: Clemont-Ferrand, France
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:黒毛和種への強化哺乳が粗飼料肥育牛の枝肉成績に及ぼす影響 (2010)
  • Author(s): 齋藤邦彦、佐久間香織、増田恭久、岡田真人、阿部剛、小林栄治、鈴木英敏、小山田幸夫、金田修一、長谷部浩行、斎藤昭、衛藤浩太郎、江原史雄、衛藤哲次、塩塚雄二、後藤貴文
  • Organizer: 第112回日本畜産学会
  • Place of Presentation: 東京
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:牛肉生産に関与した因子群の粗飼料肥育終了時の動態解析 (2010)
  • Author(s): 後藤貴文、衛藤浩太郎、齋藤邦彦、佐久間香織、増田恭久、岡田真人、阿部剛、小林栄治、鈴木英敏、金田修一、小山田幸夫、長谷部浩行、斎藤昭、塩塚雄二、江原史雄、衛藤哲次
  • Organizer: 第112回日本畜産学会
  • Place of Presentation: 東京
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:牛肉生産に関与した因子群の動態解析 (2009)
  • Author(s): 後藤貴文・衛藤浩太郎・齋藤邦彦・目時香織・増田恭久・岡田真人・阿部剛・小林栄治・鈴木英敏・金田修一・小山田幸夫・斎藤昭・塩塚雄二・江原史雄・衛藤哲次
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 那覇、沖縄
  • Year and Date: 2009-09-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:黒毛和種子牛への強化哺乳が粗飼料肥育期の発育に及ぼす影響 (2009)
  • Author(s): 齋藤邦彦・目時香織・増田恭久・岡田真人・阿部剛・小林栄治・鈴木英敏・金田修一・小山田幸夫・斎藤昭・衛藤浩太郎・中村好徳・江原史雄・衛藤哲次・後藤貴文
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 那覇、沖縄
  • Year and Date: 2009-09-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:第一胃内性状および細菌叢に及ぼす影響 (2009)
  • Author(s): 小池聡・齋藤邦彦・目時香織・増田恭久・岡田真人・阿部剛・小林栄治・鈴木英敏・金田修一・小山田幸夫・斎藤昭・衛藤浩太郎・江原史雄・衛藤哲次・塩塚雄二・後藤貴文
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 那覇、沖縄
  • Year and Date: 2009-09-29
• [Presentation] 哺乳期に摂取する代用乳の量および質の差異が黒毛和種雄子牛の生理形態に与える影響 (2009)
  • Author(s): 松田謙一郎、後藤貴文, ら
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 沖縄県(琉球大学)
  • Year and Date: 2009-09-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:牛肉生産に関与した因子群の動態解析 (2009)
  • Author(s): 後藤貴文, ら
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 沖縄県(琉球大学)
  • Year and Date: 2009-09-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:黒毛和種子牛への強化哺乳が粗飼料肥育期の発育に及ぼす影響 (2009)
  • Author(s): 齋藤邦彦、後藤貴文, ら
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 沖縄県(琉球大学)
  • Year and Date: 2009-09-29
• [Presentation] 初期成長期の代謝生理的インプリンティング効果の解明:第一胃内性状および細菌叢に及ぼす影響 (2009)
  • Author(s): 小池聡、後藤貴文, ら
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 沖縄県(琉球大学)
  • Year and Date: 2009-09-29
• [Presentation] ウシ初期成長期の代謝生理的インプリンティング効果の解明 : 牛肉生産に関与した遺伝子群の動態解析による体質制御法の検討 (2009)
  • Author(s): 衛藤浩太郎, 後藤貴文ら
  • Organizer: 第110回日本畜産学会
  • Place of Presentation: 神奈川県 (日本大学)
  • Year and Date: 2009-03-27
• [Presentation] 哺乳期に摂取する代用乳の量および質の差異が黒毛和種雄子牛の生理形態に与える影響 (2009)
  • Author(s): 松田謙一郎、阿比留真吾、木下正徳、衛藤浩太郎、齋藤邦彦、佐久間香織、増田恭久、岡田真人、阿部剛、小林栄治、鈴木英敏、金田修一、小山田幸夫、齋藤昭、塩塚雄二、江原史雄、衛藤哲次、後藤貴文
  • Organizer: 第111回日本畜産学会
  • Place of Presentation: 那覇、沖縄
• [Presentation] The Creation of a Good Quality Production System to Produce Safe Beef in Japan by Regulating the Constitution of Cattle and Feeding Grass: Metabolic lmprinting by Nutrition manipulation and Utilization of domestic grass resources. (2009)
  • Author(s): 後藤貴文
  • Organizer: 中国農業大学における牛肉生産セミナー(招待講演)
  • Place of Presentation: 北京、中国
• [Presentation] ウシ初期成長期の代謝生理的インプリンティング効果の解明:牛肉生産に関与した遺伝子群の動態解析による体質制御法の検討 (2009)
  • Author(s): 衛藤浩太郎・衛藤哲次・中村好徳・江原史雄・目時香織・増田恭久・岡田真人・阿部剛・小林栄治・鈴木英敏・金田修一・斎藤昭・後藤貴文
  • Organizer: 第110回日本畜産学会
  • Place of Presentation: 日本大学
• [Presentation] 体質制御による国内草資源高度活用型の革新的牛飼養システムの開発 (2008)
  • Author(s): 後藤貴文
  • Organizer: 第3回家畜DNA西郷シンポジウム
  • Place of Presentation: 福島県西白河郡 家畜改良センターにて
  • Year and Date: 2008-10-09
• [Presentation] A Novel Beef Production System Based on Grass Resources by Applying Metabolic Imprinting. 2008. (2008)
  • Author(s): Gotoh T., T.Fumita, T.Etoh, Y.Sshiotsuka, K.Hayashi, Y.Nakamura, J.Wegner.
  • Organizer: The Proceeding of International Symposium of Interdependencies between upland and lowland agriculture and resource management, 19-20.
  • Place of Presentation: Stuttgart Germany
• [Presentation] Metabolic Imprinting by Nutrition manipulation and Utilization of Domestic Grass Resources. (2008)
  • Author(s): Gotoh T., T.Fumita, T.Etoh, K.Hayashi, Y.Shiotsuka, Y-N.Nakamura, J.Wegner, M-A. Hattori.
  • Organizer: The proceeding of the 5th international joint symposium between Japan and Korea, "the recent status and perspectives of food system, agricultural environment and biology", 278:283.
  • Place of Presentation: Daejeon, Karea