Immunological regulation of the female reproductive tract to establish an efficient new artificial insemination system in mammals
| Project/Area Number |
20380154
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Okayama University |
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Principal Investigator |
FUNAHASHI Hiroaki Okayama University, 大学院・自然科学研究科, 教授 (50284089)
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| Co-Investigator(Kenkyū-buntansha) |
KONDOU Yasuhiro 岡山大学, 大学院・自然科学研究科, 教授 (90108126)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Keywords | 多核白血球 / 精子 / ウシ / ブタ / カフェイン / 精漿 / 卵黄 / 人工授精 / ラット |
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| Research Abstract |
In the female reproductive tracts, immunological system exists to remove sperm from the tract rapidly after mating or artificial insemination. In the present study, we could make clear that both phagocytotic and chemotactic activities of bovine and porcine polymorphonuclear leukocytes (PMNs), which mainly perform in the system, are stimulated in the presence of fresh serum and decreased in the presence of caffeine, heparin, and seminal plasma. Furthermore, PMNs phagocytize equally both active motile and dead sperm.
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Report
(4 results)
Research Products
(22 results)
