Longitudinal genetic epidemiological study for cardiovascular diseases based on Japanese general population participated in medical check-up process of Ehime University Anti-aging doc.

• Project/Area Number: 20390185
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Kyoto University (2012); Ehime University (2008-2011)
• Principal Investigator: TABARA Yasuharu 京都大学, 大学院・医学研究科, 准教授 (00268749)
• Co-Investigator(Kenkyū-buntansha): MIKI Tetsuro 愛媛大学, プロテオ医学研究センター, 教授 (00174003) ; KOHARA Katsuhiko 愛媛大学, 大学院・医学系研究科, 准教授 (30260384) ; OSAWA Haruhiko 愛媛大学, 大学院・医学系研究科, 教授 (90294800)
• Project Period (FY): 2008 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000); Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2008: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
• Keywords: 動脈硬化 / 長期縦断疫学研究 / ゲノム / 動脈硬化性疾患 / 長期縦断研究

Research Abstract

In order to clarify possible associations between atheroscrelotic diseases and relating risk factors, we conducted a cohort study based on general community-residents. As shown in the results section, we found several inter-relationships among visceral obesity, insulin resistance, atherosclerosis, sarcopenia, asymptomatic cerebral diseases, cognitive function,and genetic variations.

Research Products

• [Journal Article] Positive natural selection of TRIB2, a novel gene that influences visceral fat accumulation, in East Asia. (2013)
  • Author(s): Nakayama K, Ogawa A, Miyashita H, Tabara Y, Igase M, Kohara K, Miki T, Kagawa Y, Yanagisawa Y, Katashima M, Onda T, Okada K, Fukushima S, Iwamoto S
  • Journal Title: Hum Genet Volume: 132 Issue: 2 Pages: 201-217
  • DOI: 10.1007/s00439-012-1240-9
  • Peer Reviewed
• [Journal Article] Association of Chr17q25 with cerebral white matter hyperintensities and cognitive impairment: the J-SHIPP study (2013)
  • Author(s): Tabara Y, Igase M, Okada Y, Nagai T, Uetani E, Kido T, Ochi N, Takita R, Yamamoto M, Kohara K, Miki T
  • Journal Title: Eur J Neurol Volume: 20 Issue: 5 Pages: 860-882
  • DOI: 10.1111/j.1468-1331.2012.03879.x
  • Peer Reviewed
• [Journal Article] Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP Toon Health Study (2012)
  • Author(s): Tabara Y, Igase M, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Okada Y, Hitsumoto S, Onuma H, Nagai T, Takata Y, Uetani E, Takita R, Kido T, Ochi N, Osawa H, Tanigawa T, Miki T
  • Journal Title: Clin Hemorheol Microcirc Volume: in press Issue: 3 Pages: 297-311
  • DOI: 10.3233/ch-2012-1634
  • NAID: 120005366009
  • Peer Reviewed
• [Journal Article] Atherosclerotic indices for the prediction of cognitive impairment in a middle-aged to elderly general population: shimanami health promoting program study (2012)
  • Author(s): Kohara K, Igase M, Tabara Y, Miki T
  • Journal Title: J Am Geriatr Soc Volume: 60 Issue: 10 Pages: 1996-1997
  • DOI: 10.1111/j.1532-5415.2012.04184.x
  • Peer Reviewed
• [Journal Article] Postprandial hypertension, an overlooked risk marker for arteriosclerosis (2012)
  • Author(s): Uetani E, Tabara Y, Igase M, Guo H, Kido T, Ochi N, Takita R, Kohara K, Miki T
  • Journal Title: Atherosclerosis. Volume: 224 Issue: 2 Pages: 500-505
  • DOI: 10.1016/j.atherosclerosis.2012.07.015
  • NAID: 120004873860
  • Peer Reviewed
• [Journal Article] A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval (2012)
  • Author(s): Kim JW, Hong KW, Go MJ, Kim SS, Tabara Y, Kita Y, Tanigawa T, Cho YS, Han BG, Oh B
  • Journal Title: Am J Hum Genet Volume: 91 Issue: 1 Pages: 180-184
  • DOI: 10.1016/j.ajhg.2012.05.019
  • Peer Reviewed
• [Journal Article] Liver Enzyme and Adipocytokine Profiles are Synergistically Associated with Insulin Resistance: the J-SHIPP Study (2012)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Takita R, Kohara K, Miki T.
  • Journal Title: Journal of Atherosclerosis and Thrombosis Volume: 19 Issue: 6 Pages: 577-584
  • DOI: 10.5551/jat.11924
  • NAID: 130004444612
  • ISSN: 1340-3478, 1880-3873
• [Journal Article] Potential utility of soluble p3-alcadeinα plasma levels as a biomarker for sporadic Alzheimer's disease (2012)
  • Author(s): Kamogawa K, Kohara K, Tabara Y, Takita R, Miki T, Konno T, Hata S, Suzuki T
  • Journal Title: J Alzheimers Dis Volume: 31 Issue: 2 Pages: 421-8
  • DOI: 10.3233/jad-2012-120601
  • Peer Reviewed
• [Journal Article] Arterial stiffness in sarcopenic visceral obesity in the elderly: J-SHIPP study (2012)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: Int J Cardiol Volume: 158 Issue: 1 Pages: 146-148
  • DOI: 10.1016/j.ijcard.2012.04.033
  • Peer Reviewed
• [Journal Article] Perceived age of facial features is a significant diagnosis criterion for age-related carotid atherosclerosis in Japanese subjects: J-SHIPP study (2012)
  • Author(s): Kido M, Kohara K, Miyawaki S, Tabara Y, Igase M, Miki T
  • Journal Title: Geriatr Gerontol Int Volume: 12 Issue: 4 Pages: 733-740
  • DOI: 10.1111/j.1447-0594.2011.00824.x
  • Peer Reviewed
• [Journal Article] Leptin in sarcopenic visceral obesity: possible link between adipocytes and myocytes (2011)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: PLoS One Volume: 6 Issue: 9 Pages: e24633-e24633
  • DOI: 10.1371/journal.pone.0024633
  • Peer Reviewed
• [Journal Article] TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance (2011)
  • Author(s): Yamazaki D, Tabara Y, Kita S, Hanada H, Komazaki S, Naitou D, Mishima A, Nishi M, Yamamura H, Yamamoto S, Kakizawa S, Miyachi H, Yamamoto S, Miyata T, Kawano Y, Kamide K, Ogihara T, Hata A, Umemura S, Soma M, Takahashi N, Imaizumi Y, Miki T, Iwamoto T, Ta
  • Journal Title: Cell Metab Volume: 14 Issue: 2 Pages: 231-241
  • DOI: 10.1016/j.cmet.2011.05.011
  • NAID: 120003255678
  • URL: http://hdl.handle.net/2433/143634
  • Peer Reviewed
• [Journal Article] International Consortium for Blood Pressure Genome-Wide Association Studies. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk (2011)
  • Journal Title: Nature. Volume: 478 Issue: 7367 Pages: 103-109
  • DOI: 10.1038/nature10405
  • Peer Reviewed
• [Journal Article] Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in East Asians (2011)
  • Author(s): Yamori Y
  • Journal Title: Nat Genetics Volume: 43 Issue: 6 Pages: 531-538
  • DOI: 10.1038/ng.834
  • Peer Reviewed
• [Journal Article] Genotype risk score of common susceptible variants for prediction of type 2 diabetes mellitus in Japanese: the Shimanami Health Promoting Program (J-SHIPP study). Development of type 2 diabetes mellitus and genotype risk score (2011)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Makino H, Kohara K, Miki T
  • Journal Title: Metabolism Volume: 60(11) Issue: 11 Pages: 1634-40
  • DOI: 10.1016/j.metabol.2011.03.014
  • Peer Reviewed
• [Journal Article] Relatively lower central aortic pressure in patients with impaired insulin sensitivity and resistance: the Toon Health Study (2011)
  • Author(s): Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
  • Journal Title: J Hypertens Volume: 29 Issue: 10 Pages: 1948-54
  • DOI: 10.1097/hjh.0b013e32834abd06
  • Peer Reviewed
• [Journal Article] Leptin in sarcopenic visceral obesity : possible link between adipocytes and myocytes (2011)
  • Author(s): Kohara K, et al
  • Journal Title: PLoS One Volume: 6
  • Peer Reviewed
• [Journal Article] Genotype risk score of common susceptible variants for prediction of type 2 diabetes mellitus in Japanese (2011)
  • Author(s): Tabara Y, et al
  • Journal Title: Metabolism Volume: 60 Pages: 1634-1640
  • Peer Reviewed
• [Journal Article] Relatively lower central aortic pressure in patients with impaired insulin sensitivity and resistance (2011)
  • Author(s): Tabara Y, et al
  • Journal Title: J Hypertens Volume: 29 Pages: 1948-1954
  • Peer Reviewed
• [Journal Article] Abdominal fat, adipose-derived hormones and mild cognitive impairment: the J-SHIPP study (2010)
  • Author(s): Kamogawa K, Kohara K, Tabara Y, Uetani E, Nagai T, Yamamoto M, Igase M, Miki T
  • Journal Title: Dement Geriatr Cogn Disord Volume: 30 Issue: 5 Pages: 432-9
  • DOI: 10.1159/000321985
• [Journal Article] Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project. (2010)
  • Author(s): Tabara Y, Kohara K, Kita Y, Hirawa N, Katsuya T, Ohkubo T, Hiura Y, Tajima A, Morisaki T, Miyata T, Nakayama T, Takashima N, Nakura J, Kawamoto R, Takahashi N, Hata A, Soma M, Imai Y, Kokubo Y, Okamura T, Tomoike H, Iwai N, Ogihara T, Inoue I, Tokunaga K
  • Journal Title: Hypertension. Volume: 56 Issue: 5 Pages: 973-980
  • DOI: 10.1161/hypertensionaha.110.153429
• [Journal Article] Association of four genetic loci with uric acid levels and reduced renal function: the J-SHIPP Suita study (2010)
  • Author(s): Tabara Y, Kohara K, Kawamoto R, Hiura Y, Nishimura K, Morisaki T, Kokubo Y, Okamura T, Tomoike H, Iwai N, Miki T
  • Journal Title: Am J Nephrol Volume: 32 Issue: 3 Pages: 279-286
  • DOI: 10.1159/000318943
• [Journal Article] The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population (2010)
  • Author(s): Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H
  • Journal Title: J Hum Genet Volume: 55 Issue: 9 Pages: 600-604
  • DOI: 10.1038/jhg.2010.75
  • NAID: 10030736734
• [Journal Article] Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men (2010)
  • Author(s): Ochi M, Kohara K, Tabara Y, Kido T, Uetani E, Ochi N, Igase M, Miki T.
  • Journal Title: Atherosclerosis. Volume: 212 Issue: 1 Pages: 327-332
  • DOI: 10.1016/j.atherosclerosis.2010.05.026
• [Journal Article] Postural instability is associated with brain atrophy and cognitive impairment in the elderly: the J-SHIPP study (2010)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Miki T, Kohara K
  • Journal Title: Dement Geriatr Cogn Disord Volume: 29 Issue: 5 Pages: 379-387
  • DOI: 10.1159/000255106
• [Journal Article] A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population (2010)
  • Author(s): Onuma H, Tabara Y, Kawamura R, Tanaka T, Ohashi J, Nishida W, Takata Y, Ochi M, Yamada K, Kawamoto R, Kohara K, Miki T, Makino H, Osawa H
  • Journal Title: PLoS One Volume: 5 Issue: 3 Pages: e9718-e9718
  • DOI: 10.1371/journal.pone.0009718
• [Journal Article] Quadriceps sarcopenia and visceral obesity are risk factors for postural instability in the middle-aged to elderly population (2010)
  • Author(s): Ochi M, Tabara Y, Kido T, Uetani E, Ochi N, Igase M, Miki T, Kohara K
  • Journal Title: Geriatr Gerontol Int Volume: 10 Issue: 3 Pages: 233-243
  • DOI: 10.1111/j.1447-0594.2010.00610.x
  • NAID: 10027272421
• [Journal Article] Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population? (2010)
  • Author(s): Osawa H, Tabara Y, Ohashi J, Kawamura R, Onuma H, Makino H
  • Journal Title: Diabetologia. Volume: 53 Issue: 4 Pages: 795-797
  • DOI: 10.1007/s00125-010-1665-4
• [Journal Article] Associations between short one-leg standing time and speed of sound of calcaneal bone in a general population: the Shimanami Health Promoting Program (J-SHIPP) study (2010)
  • Author(s): Kido T, Tabara Y, Igase M, Uetani E, Ochi N, Miki T, Kohara K
  • Journal Title: Geriatr Gerontol Int Volume: 10 Issue: 2 Pages: 138-144
  • DOI: 10.1111/j.1447-0594.2009.00565.x
  • NAID: 10027272046
• [Journal Article] Association of central systolic blood pressure with intracerebral small vessel disease in Japanese (2010)
  • Author(s): Ochi N, Kohara K, Tabara Y, Nagai T, Kido T, Uetani E, Ochi M, Igase M, Miki T
  • Journal Title: Am J Hypertens Volume: 23 Issue: 8 Pages: 889-894
  • DOI: 10.1038/ajh.2010.60
• [Journal Article] Cross-sectional characterization of all classes of antihypertensives in terms of central blood pressure in Japanese hypertensive patients (2010)
  • Author(s): Miyashita H, Aizawa A, Hashimoto J, Hirooka Y, Imai Y, Kawano Y, Kohara K, Sunagawa K, Suzuki H, Tabara Y, Takazawa K, Takenaka T, Yasuda H, Shimada K
  • Journal Title: Am J Hypertens Volume: 23 Issue: 3 Pages: 260-268
  • DOI: 10.1038/ajh.2009.255
• [Journal Article] Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly: the J-SHIPP study (2010)
  • Author(s): Guo H, Tabara Y, Igase M, Yamamoto M, Ochi N, Kido T, Uetani E, Taguchi K, Miki T, Kohara K
  • Journal Title: Hypertens Res Volume: 33 Issue: 1 Pages: 32-36
  • DOI: 10.1038/hr.2009.172
  • NAID: 10026125611
• [Journal Article] Association of four genetic loci with uric acid levels and reduced renal function : the J-SHIPP Suita study. (2010)
  • Author(s): Tabara Y, Kohara K, Kawamoto R, Hiura Y, Nishimura K, Morisaki T, Kokubo Y, Okamura T, Tomoike H, Iwai N, Miki T.
  • Journal Title: Am J Nephrol. 32 Pages: 279-286
  • Peer Reviewed
• [Journal Article] Postural instability is associated with brain atrophy and cognitive impairment in the elderly : the J-SHIPP study. (2010)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Miki T, Kohara K.
  • Journal Title: Dement Geriatr Cogn Disord. 29 Pages: 379-387
  • Peer Reviewed
• [Journal Article] Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly : the J-SHIPP study. (2010)
  • Author(s): Guo H, Tabara Y, Igase M, Yamamoto M, Ochi N, Kido T, Uetani E, Taguchi K, Miki T, Kohara K.
  • Journal Title: Hypertens Res. 33 Pages: 32-36
  • NAID: 10026125611
  • Peer Reviewed
• [Journal Article] Hemoglobin Is Associated with Serum High Molecular Weight Adiponectin in Japanese Community-Dwelling Persons. (2010)
  • Author(s): Kawamoto R, et al.
  • Journal Title: J Atheroscler Thromb Volume: (In press)
  • Peer Reviewed
• [Journal Article] High-sensitivity C-reactive protein and gamma-glutamy1 transferase levels are synergistically associated with metabolic syndrome in community-dwelling persons. (2010)
  • Author(s): Kawamoto R, et al.
  • Journal Title: Cardiovasc Diabetol. Volume: 9 Pages: 87-87
  • Peer Reviewed
• [Journal Article] Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults. (2010)
  • Author(s): Kawamoto R, et al.
  • Journal Title: Lipids Health Dis. Volume: 9 Pages: 138-138
  • Peer Reviewed
• [Journal Article] Abdominal fat, adipose-derived hormones and mild cognitive impairment : the J-SHIPP study. (2010)
  • Author(s): Kamogawa K, et al.
  • Journal Title: Dement Geriatr Cogn Disord. Volume: 30 Pages: 432-9
  • Peer Reviewed
• [Journal Article] Common variants in the ATP2B1 gene are associated with susceptibility to hypertension : the Japanese Millennium Genome Project. (2010)
  • Author(s): Tabara Y, et al.
  • Journal Title: Hypertension. Volume: 56 Pages: 973-80
  • Peer Reviewed
• [Journal Article] Alcohol drinking status is associated with serum high molecular weight adiponectin in comnunity-dwelling Japanese men. (2010)
  • Author(s): Kawamoto R, et al.
  • Journal Title: J Atheroscler Thromb. Volume: 17 Pages: 953-62
  • Peer Reviewed
• [Journal Article] Serum high molecular weight adiponectin is associated with mild renal dysfunction in Japanese adults. (2010)
  • Author(s): Kawamoto R, et al.
  • Journal Title: J Atheroscler Thromb. Volume: 17 Pages: 1141-8
  • Peer Reviewed
• [Journal Article] Association of four genetic loci with uric acid levels and reduced renal function : the J-SHIPP Suita study. (2010)
  • Author(s): Tabara Y, et al.
  • Journal Title: Am J Nephrol. Volume: 32 Pages: 279-86
  • Peer Reviewed
• [Journal Article] The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population. (2010)
  • Author(s): Onuma H, et al.
  • Journal Title: J Hum Genet. Volume: 55 Pages: 600-4
  • Peer Reviewed
• [Journal Article] Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men. (2010)
  • Author(s): Ochi M, et al.
  • Journal Title: Atherosclerosis. Volume: 212 Pages: 327-32
  • Peer Reviewed
• [Journal Article] Postural instability is associated with brain atrophy and cognitive impairment in the elderly : the J-SHIPP study. (2010)
  • Author(s): Kido T, et al.
  • Journal Title: Dement Geriatr Cogn Disord. Volume: 29 Pages: 379-87
  • Peer Reviewed
• [Journal Article] A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population. (2010)
  • Author(s): Onuma H, et al.
  • Journal Title: PLoS One. Volume: 5
  • Peer Reviewed
• [Journal Article] Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population? (2010)
  • Author(s): Osawa H, et al.
  • Journal Title: Diabetologia. Volume: 53 Pages: 795-7
  • Peer Reviewed
• [Journal Article] Associations between short one-leg standing time and speed of sound of calcaneal bone in a general population : the Shimanami Health Promoting Program(J-SHIPP)study (2010)
  • Author(s): Kido T, et al.
  • Journal Title: Geriatr Gerontol Int. 10 Pages: 138-44
  • Peer Reviewed
• [Journal Article] Association of Central Systolic Blood Pressure With Intracerebral Small Vessel Disease in Japanese (2010)
  • Author(s): Ochi N, et al.
  • Journal Title: Am J Hypertens (In press)
  • Peer Reviewed
• [Journal Article] Quadriceps sarcopenia and visceral obesity are risk factors for postural instability in the middle-aged to elderly population (2010)
  • Author(s): Ochi M, et al.
  • Journal Title: Geriatr Gerontol Int. (In press)
  • Peer Reviewed
• [Journal Article] Insulin resistance and prevalence of prehypertension and hypertension among community-dwelling persons (2010)
  • Author(s): Kawamoto R, et al
  • Journal Title: J Atheroscler Thromb 17 Pages: 148-55
  • Peer Reviewed
• [Journal Article] Smoking status is associated with serum high molecular adiponectin levels in community-dwelling Japanese men (2010)
  • Author(s): Kawamoto R, et al
  • Journal Title: J Atheroscler Thromb 17 Pages: 423-30
  • Peer Reviewed
• [Journal Article] Cross-sectional characterization of all classes of antihypertensives in terms of central blood pressure in Japanese hypertensive patients (2010)
  • Author(s): Miyashita H, et al.
  • Journal Title: Am J Hypertens 23(In press)
  • Peer Reviewed
• [Journal Article] Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly : the J-SHIPP study (2010)
  • Author(s): Guo H, et al.
  • Journal Title: Hypertens Res. 33 Pages: 32-6
  • Peer Reviewed
• [Journal Article] Silent cerebral microbleeds associated with arterial stiffness in an apparently healthy subject (2009)
  • Author(s): Ochi N, Tabara Y, Igase M, Nagai T, Kido T, Miki T, Kohara K
  • Journal Title: Hypertens Res Volume: 32 Issue: 4 Pages: 255-260
  • DOI: 10.1038/hr.2009.13
  • NAID: 10024830420
• [Journal Article] Asymptomatic cerebral microbleeds seen in healthy subjects have a strong association with asymptomatic lacunar infarction (2009)
  • Author(s): Igase M, Tabara Y, Igase K, Nagai T, Ochi N, Kido T, Nakura J, Sadamoto K, Kohara K, Miki T
  • Journal Title: Circ J Volume: 73(3) Pages: 530-3
  • NAID: 110007126723
• [Journal Article] Composition of lower extremity in relation to a high ankle-brachial index. (2009)
  • Author(s): Tabara Y, Igase M, Kido T, Ochi N, Miki T, Kohara K.
  • Journal Title: J Hypertens. 27 Pages: 167-173
  • Peer Reviewed
• [Journal Article] Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. (2009)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, Kohara K, Makino H.
  • Journal Title: Diabetes. 58 Pages: 493-498
  • Peer Reviewed
• [Journal Article] Serum gamma-glutamyl transferase levels are associated with metabolic syndrome in community-dwelling individuals (2009)
  • Author(s): Kawamoto R, et al
  • Journal Title: J Atheroscler Thro 16 Pages: 355-62
  • Peer Reviewed
• [Journal Article] Alcohol consumption is associated with decreased insulin resistance independent of body mass index in Japanese community-dwelling men (2009)
  • Author(s): Kawamoto R, et al
  • Journal Title: Tohoku J Exp Mod 218 Pages: 331-7
  • Peer Reviewed
• [Journal Article] Silent cerebral microbleeds associated with arterial stiffness in an apparently healthy subject (2009)
  • Author(s): Ochi N, et al.
  • Journal Title: Hypertens Res 32 Pages: 255-60
  • Peer Reviewed
• [Journal Article] Asymptomatic cerebral microbleeds seen in healthy subjects have a strong association with asymptomatic lacunar infarction (2009)
  • Author(s): Igase M, et al
  • Journal Title: Circ J 73 Pages: 530-3
  • Peer Reviewed
• [Journal Article] Clinical usefulness of the second peak of radial systolic blood pressure for estimation of aortic systolic blood pressure (2009)
  • Author(s): Kohara K, et al.
  • Journal Title: J Hum Hypertens 23 Pages: 538-45
  • Peer Reviewed
• [Journal Article] No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population (2008)
  • Author(s): Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K
  • Journal Title: Obesity Volume: 16 Issue: 1 Pages: 211-215
  • DOI: 10.1038/oby.2007.25
• [Journal Article] Resistin, glomerular filtration rate, and insulin resistance (2008)
  • Author(s): Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K
  • Journal Title: Hypertension Volume: 51 Issue: 2
  • DOI: 10.1161/hypertensionaha.107.102046
• [Journal Article] Blood pressure is the main determinant of the reflection wave in patients with type 2 diabetes (2008)
  • Author(s): Tomita H, Kawamoto R, Tabara Y, Miki T, Kohara K
  • Journal Title: Hypertens Res Volume: 31 Issue: 3 Pages: 493-499
  • DOI: 10.1291/hypres.31.493
  • NAID: 10021933845
• [Journal Article] Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population: the Shimanami Health Promoting Program Study (2008)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Tachibana-Iimori R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K
  • Journal Title: J Clin Endocrinol Metab Volume: 93 Issue: 3 Pages: 715-722
  • DOI: 10.1210/jc.2007-0397
• [Journal Article] No association of INSIG2 gene rs7566605 polymorphism with being overweight in Japanese population (2008)
  • Author(s): Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K
  • Journal Title: Obesity 16 Pages: 211-215
  • Peer Reviewed
• [Journal Article] Resistin, glomerular filtration rate, and insulin resistance. (2008)
  • Author(s): Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K.
  • Journal Title: Hypertension 51(ell)
  • Peer Reviewed
• [Journal Article] Blood pressure is the main reterminant of the reflection wave in patients with type 2 diabetes (2008)
  • Author(s): Tomita H, Kawamoto R, Tabara Y, Miki T, Kohara K
  • Journal Title: Hypertens Res 31 Pages: 493-500
  • Peer Reviewed
• [Journal Article] An association between decreased estimated glomerular filtration rate and arterial stiffness (2008)
  • Author(s): Kawamoto R, Kohara K, Tabara Y, Miki T, Ohtsuka N, Kusunoki T, Yorimitsu N.
  • Journal Title: Intern Med 47 Pages: 593-598
  • NAID: 130000080057
  • Peer Reviewed
• [Journal Article] Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population (2008)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Tachibana R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K.
  • Journal Title: J Clin Endocrinol Metab. 93 Pages: 715-722
  • Peer Reviewed
• [Journal Article] An association between metabolic syndrome and the estimated glomerular filtration rate. (2008)
  • Author(s): Kawamoto R, Kohara K, Tabara Y, Miki T.
  • Journal Title: Intern Med. 47 Pages: 1399-1406
  • NAID: 130000078949
  • Peer Reviewed
• [Journal Article] Association between serum gamma-glutamyl transferase level and prehypertension among community-dwelling men. (2008)
  • Author(s): Kawamoto R, Kohara K, Tabara Y, Kusunoki T, Otsuka N, Miki T.
  • Journal Title: Tohoku J Exp Med. 216 Pages: 213-221
  • NAID: 10025103969
  • Peer Reviewed
• [Presentation] 老化・生活習慣病の関連遺伝子解析 (2012)
  • Author(s): 田原康玄, 他
  • Organizer: 日本老年医学会第23回四国地方会及び教育企画
  • Place of Presentation: 松山(招待講演)
  • Year and Date: 2012-02-18
• [Presentation] 見た目年齢と加齢性血圧変化 (2012)
  • Author(s): 小原克彦・城戸美和子・宮脇さおり・田原康玄・伊賀瀬道也・三木哲郎
  • Organizer: 第１回臨床高血圧フォーラム
  • Place of Presentation: 大阪
• [Presentation] ヘマトクリットとインスリン抵抗性，インスリン感受性ならびに無症候性脳血管障害との関連 (2012)
  • Author(s): 田原康玄・大澤春彦・伊賀瀬道也・斉藤 功・西田 亙・小原克彦・櫻井 進 川本龍一・上谷英里・櫃本真一・大沼 裕・多喜田理絵・高田康徳・永井勅久 岡田陽子・城戸知子・越智南美子・谷川武・三木哲郎
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: 横浜
• [Presentation] 加齢と日中の眠気 (2012)
  • Author(s): 永井勅久・小原克彦・田原康玄・岡田陽子・越智雅之・城戸知子・ 上谷英里・城戸美和子・伊賀瀬道也・三木哲郎
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 下肢筋力量推定における腸腰筋インデックスの有用性についての検討 (2012)
  • Author(s): 越智雅之・小原克彦・篠原奈子・岡田陽子・永井勅久・多喜田理絵・伊賀瀬道也・三木哲郎・田原康玄
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 血管老化指標としての見た目年齢 (2012)
  • Author(s): 小原克彦・田原康玄・永井勅久・越智雅之・岡田陽子・篠原奈子・多喜田理絵・伊賀瀬道也・三木哲郎
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 高血圧のGWAS 世界のトレンドを探る (2012)
  • Author(s): 田原康玄
  • Organizer: 第33回日本臨床薬理学会学術総会
  • Place of Presentation: 沖縄
  • Invited
• [Presentation] 中心血圧に対するインスリン抵抗性・感受性の影響 (2012)
  • Author(s): 田原康玄, 他
  • Organizer: 第22回日本疫学会学術総会
  • Place of Presentation: 東京
• [Presentation] 運動による高血圧・動脈壁硬化の予防と改善 (2012)
  • Author(s): 田原康玄, 他
  • Organizer: 第89回日本生理学会大会
  • Place of Presentation: 松本(招待講演)
• [Presentation] Reduced lower extremity muscle mass is an independent risk factor for incidence of falls (2011)
  • Author(s): Tabara Y, Igase M, Uetani E, Kido T, Ochi N, Kohara K, Miki T
  • Organizer: International Conference on Sarcopenia Research
  • Place of Presentation: Toulouse.
• [Presentation] Postprandial hypertension; an overlooked risk factor for arterial stiffness (2011)
  • Author(s): Uetani E, Tabara Y, Igase M, Ochi N, Kido T, Miki T, Kohara K
  • Organizer: Council for High Blood Pressure Research
  • Place of Presentation: Orlando
• [Presentation] Relatively lower central aortic pressure in subjects with impaired insulin sensitivity and resistance: The Toon Health Study (2011)
  • Author(s): Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
  • Organizer: Council for High Blood Pressure Research
  • Place of Presentation: Orlando
• [Presentation] 無症候性ラクナ梗塞および動脈壁硬貨と頸動脈の機械的なストレスに関する検討 (2011)
  • Author(s): 岡田陽子, 他
  • Organizer: 第52回日本神経学会総会
  • Place of Presentation: 名古屋
• [Presentation] 一般住民における認知機能障害と関連する動脈硬化指数 (2011)
  • Author(s): 小原克彦, 他
  • Organizer: 第52回日本神経学会総会
  • Place of Presentation: 名古屋
• [Presentation] 一般地域住民において血中レジスチンはエンドセリン-1の一塩基多型(SNP)と関連する (2011)
  • Author(s): 川村良一, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 札幌
• [Presentation] 一般地域住民においてレジスチンは一塩基多型(SNP)-420及びSNP-358は代謝関連の量的形質とは関連しない (2011)
  • Author(s): 大澤春彦, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 札幌
• [Presentation] レジスチンとHDLコレステロールとの関連はSNP-420依存的である (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 札幌
• [Presentation] 一般地域住民における非肥満睡眠時無呼吸と脈波伝播速度 (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 弟53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 下肢筋肉量推定におけるエコー計測法の有用性についての検討 (2011)
  • Author(s): 越智雅之, 他
  • Organizer: 弟53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] アディポネクチンとインスリン抵抗性との関連にはCDH13遺伝子多型が交絡する (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 第18回日本遺伝子診療学会大会
  • Place of Presentation: 京都
• [Presentation] Reduced lower extremity muscle mass is an independent risk factor for incidence of falls (2011)
  • Author(s): Tabara Y., et al
  • Organizer: International Conference on Sarcopenia Research
  • Place of Presentation: フランス
• [Presentation] Postprandial Hypertension, an Overlooked Risk Factor for Arterial Stiffness (2011)
  • Author(s): Uetani E, et al
  • Organizer: High Blood Pressure Research 2011
  • Place of Presentation: オーランドUSA
• [Presentation] Arterial Stiffness Associates with Cognitive Impairment and Brain Atrophy (2011)
  • Author(s): Kido M, et al
  • Organizer: High Blood Pressure Research 2011
  • Place of Presentation: オーランドUSA
• [Presentation] Relatively Lower Central Aortic Pressure in Subjects with Impaired Insulin Sensitivity and Resistance (2011)
  • Author(s): Tabara Y, et al
  • Organizer: High Blood Pressure Research 2011
  • Place of Presentation: オーランドUSA
• [Presentation] Arterial Stiffness in Sarcopenic Obesity, the Common Form of Obesity in the Elderly : J-SHIPP Study (2011)
  • Author(s): Kohara K, et al
  • Organizer: High Blood Pressure Research 2011
  • Place of Presentation: オーランドUSA
• [Presentation] ATP2B1は日本人における高血圧感受性遺伝子である (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 第34回日本高血圧学会総会
  • Place of Presentation: 宇都宮
• [Presentation] インスリン作用の低下は中心血圧の独立した規定因子である (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 第34回日本高血圧学会総会
  • Place of Presentation: 宇都宮
• [Presentation] 高血圧感受性遺伝子ATP2B1の同定 (2011)
  • Author(s): 田原康玄, 他
  • Organizer: 日本人類遺伝学会第56回大会
  • Place of Presentation: 幕張
• [Presentation] 地域光ファイバー網を用いた血圧管理システム (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 第22回血圧管理研究会
  • Place of Presentation: 京都
  • Year and Date: 2010-12-04
• [Presentation] Postprandial hypotension as a risk factor for cognitive decline in community-dwelling elderly persons (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Yamamoto M, Kohara K, Miki T
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension
  • Place of Presentation: Vancouver
• [Presentation] Class effects of BP-lowering drugs on central blood pressure measurement (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Ochi N, Kido T, Kohara K, Miki T
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension
  • Place of Presentation: Vancouver
• [Presentation] Class effects of BP-lowering drugs on central blood pressure measurement. (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Kohara K, Miki T.
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension.
  • Place of Presentation: Vancouver, Canada
• [Presentation] Postprandial hypotension as a risk factor for cognitive decline in community-dwelling elderly persons. (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Yamamoto M, Kohara K, Miki T.
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension.
  • Place of Presentation: Vancouver, Canada
• [Presentation] Association of the functional variant in the HMGCR with LDL cholesterol in Japanese. (2010)
  • Author(s): Tabara Y, Hiura Y, Kokubo Y, Okamura T, Goto Y, Nonogi H, Miki T, Tomoike H, Iwai N.
  • Organizer: The Genomics of Common Diseases.
  • Place of Presentation: Huston, USA
• [Presentation] 無症候性ラクナ梗塞および軽度認知機能障害のリスク因子としての食事性低血圧 (2010)
  • Author(s): 上谷英里, 他
  • Organizer: 第51回日本神経学会総会
  • Place of Presentation: 東京
• [Presentation] 血中レジスチンは全ゲノム関連解析(GWAS)で同定された2型糖尿病感受性一塩基多型(SNP)THADAと関連する (2010)
  • Author(s): 大澤春彦, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 岡山
• [Presentation] レジスチンSNP-420Gが血中レジスチンを高めるためには,SNP-358Aが必要である (2010)
  • Author(s): 大沼裕, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 岡山
• [Presentation] 2型糖尿病感受性遺伝子解析におけるインスリン抵抗性の交絡 (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 岡山
• [Presentation] 日本人においてGCKRは2型糖尿病感受性遺伝子である (2010)
  • Author(s): 越智正昭, 他
  • Organizer: 弟53回日本糖尿病学会年次学術集会
  • Place of Presentation: 岡山
• [Presentation] アルツハイマー病における血中Alcadein代謝産物測定の有用性 (2010)
  • Author(s): 鴨川賢二, 他
  • Organizer: 第52回日本老年医学会学術集会・総会
  • Place of Presentation: 神戸
• [Presentation] 地域在住高齢者における食後高血糖と認知機能障害 (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 第52回日本老年医学会学術集会・総会
  • Place of Presentation: 神戸
• [Presentation] 一般地域住民における肝酵素とインスリン抵抗性 (2010)
  • Author(s): 上谷英里, 他
  • Organizer: 第52回日本老年医学会学術集会・総会
  • Place of Presentation: 神戸
• [Presentation] 地域在住の日本人男性のいて血清高分子量アディポネクチン値は喫煙により減少する (2010)
  • Author(s): 川本龍一, 他
  • Organizer: 第52回日本老年医学会学術集会・総会
  • Place of Presentation: 神戸
• [Presentation] 地域在住者における血清高分子量アディポネクチン値と脈波伝道速度との関係 (2010)
  • Author(s): 楠木智, 他
  • Organizer: 第52回日本老年医学会学術集会・総会
  • Place of Presentation: 神戸
• [Presentation] Genome-wide Association studies ; Recent advances and future direction (2010)
  • Author(s): Tabara Y
  • Organizer: 第42回日本動脈硬化学会総会・学術集会
  • Place of Presentation: 岐阜
• [Presentation] 血清尿酸値の遺伝的変動と慢性腎臓病との関連 (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 第17回日本遺伝子診療学会大会
  • Place of Presentation: 三重
• [Presentation] Class effects of BP-lowering drugs on central blood pressure measurement (2010)
  • Author(s): Uetani E, et al
  • Organizer: 23rd Scientific Meeting The International Society of Hypertension
  • Place of Presentation: Vancouver, Canada
• [Presentation] Postprandial hypotension as a risk factor for cognitive decline in community-dwelling elderly persons (2010)
  • Author(s): Uetani E, et al
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension
  • Place of Presentation: Vancouver, Canada
• [Presentation] Association of the functional variant in the HMGCR with LDL cholesterol in Japanese (2010)
  • Author(s): Tabara Y, et al
  • Organizer: The Genomics of Common Diseases
  • Place of Presentation: Huston, USA
• [Presentation] 一般地域住民における血圧日内変動と睡眠時呼吸障害に関する疫学的検討 (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 第33回日本高血圧学会総会
  • Place of Presentation: 福岡
• [Presentation] 新たな動脈硬化リスクとしてのサルコペニアの検討:J-SHIPP study (2010)
  • Author(s): 越智雅之, 他
  • Organizer: 第33回日本高血圧学会総会
  • Place of Presentation: 福岡
• [Presentation] 2型糖尿病の発症と感受性遺伝子リスクスコア一般地域住民を対象とした長期縦断ゲノム疫学研究的検討 (2010)
  • Author(s): 田原康玄, 他
  • Organizer: 日本人類遺伝学会第55回大会
  • Place of Presentation: 大宮
• [Presentation] 慢性腎臓病(CKD)のリスクとしての腎性低尿酸血症とURAT1遺伝子変異 (2009)
  • Author(s): 田原康玄, 他
  • Organizer: 第32回 日本高血圧学会総会
  • Place of Presentation: 滋賀
  • Year and Date: 2009-10-02
• [Presentation] 脂質異常症治療による脳心血管系疾患の予防～更年期女性に対するスタチン治療の動脈硬化改善作用～ (2009)
  • Author(s): 伊賀瀬道也, 他
  • Organizer: 第32回 日本高血圧学会総会
  • Place of Presentation: 滋賀
  • Year and Date: 2009-10-02
• [Presentation] Postprandial hypotension is associated with asymptomatic cerebrovascular damage in community-dwelling elderly (2009)
  • Author(s): 田原康玄, et al
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Paris, France
  • Year and Date: 2009-07-09
• [Presentation] Postural instability is-associated with brain atrophy and cognitive impairment in elderly : the J-SHIPP study (2009)
  • Author(s): Kido T, et al.
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Paris, France
  • Year and Date: 2009-07-09
• [Presentation] 高齢者の平衡機能の低下と脳萎縮ならびに認知機能との関連 (2009)
  • Author(s): 城戸知子, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 軽度認知機能障害のリスク因子としての食事性低血圧 (2009)
  • Author(s): 田原康玄, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 一般男性住民を対象とした血清 γ-GTPと高血圧前症との関係について (2009)
  • Author(s): 川本龍一, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 閉経後脂質異常症患者に対するスタチン治療の機能性動脈硬化改善作用 (2009)
  • Author(s): 伊賀瀬道也, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 大腿筋面積を指標とした高齢者における適正歩行量の試算 (2009)
  • Author(s): 田原康玄, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 腿筋肉量と認知機能との関連性に関する検討 (2009)
  • Author(s): 越智雅之, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 高齢者における食事性血圧低下と無症候性ラクナ梗塞 (2009)
  • Author(s): 田原康玄, 他
  • Organizer: 第51回日本老年医学会学術集会・総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-19
• [Presentation] 一般地域住民における中心血圧と降圧治療ならびに動脈硬化性因子との相関 (2009)
  • Author(s): 田原康玄, 他
  • Organizer: 第9回臨床血圧脈波研究会
  • Place of Presentation: 東京
  • Year and Date: 2009-05-30
• [Presentation] Postprandial hypotension is associated with asymptomatic cerebrovascular damage in community-dwelling elderly (2009)
  • Author(s): Tabara Y, Igase M, Nagai T, Kido T, Ochi N, Uetani E, Miki T, Kohara K
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Paris
• [Presentation] Postural instability is-associated with brain atrophy and cognitive impairment in elderly: the J-SHIPP study (2009)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Miki T, Kohara K
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Paris
• [Presentation] Postprandial hypotension is associated with asymptomatic cerebrovascular damage in community-dwelling elderly. (2009)
  • Author(s): Tabara Y, Igase M, Nagai T, Kido T, Ochi N, Uetani E, Miki T, Kohara K.
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics.
  • Place of Presentation: Paris, France
• [Presentation] Postural instability is-associated with brain atrophy and cognitive impairment in elderly : the J-SHIPP study. (2009)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Kohara K, Miki T.
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics.
  • Place of Presentation: Paris, France
• [Presentation] 血圧日内変動と軽度認知機能障害 (2008)
  • Author(s): 田原康玄, 郭海燕, 伊賀瀬道也, 山本美由紀, 越智南美子, 城戸知子, 上谷英里, 田口敬子, 三木哲郎, 小原克彦
  • Organizer: 第20回血圧管理研究会
  • Place of Presentation: 京都
  • Year and Date: 2008-11-29
• [Presentation] 起立によるAugmentation indexの変化と無症候性脳梗塞との相関 (2008)
  • Author(s): 田原康玄, 伊賀瀬道也, 永井勅久, 城戸知子, 越智南美子, 三木哲郎, 小原克彦
  • Organizer: 第8回臨床血圧脈波研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-06-07
• [Presentation] Urate anion exchanger gene, SLC22A12, polymorphism is associated with plasma uric acid levels but not inflammation and insulin resistance (2008)
  • Author(s): Tabara Y, Kawamoto R, Tachibana-Iimori R, Yamamoto M, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin
• [Presentation] Plasma leptin levels and orthostatic hypertension in the elderly (2008)
  • Author(s): Tabara Y, Igase M, Tomoko K, Namiko O, Tetsuro M, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin
• [Presentation] Composition of the lower extremity in relation to a high ankle-brachial index: The J-SHIPP study (2008)
  • Author(s): Tabara Y, Igase M, Kido T, Ochi N, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin
• [Presentation] Orthostatic decline in augmentation index and late systolic blood pressure is a risk factor for silent lacunar infarction (2008)
  • Author(s): Tabara Y, Igase M, Nagai T, Kido T, Ochi N, Tetsuro M, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin
• [Presentation] Nocturnal blood pressure and mild cognitive impairment in elderly (2008)
  • Author(s): Tabara Y, Igase M, Yamamoto M, Nakura J, Ochi N, Kido T, Miki T, Kohara K
  • Organizer: 62nd Council for High Blood Pressure Research
  • Place of Presentation: Atlanta
• [Presentation] メタボリックシンドロームに対する高分子量アディポネクチンと高感度CRPとの相乗的相関 (2008)
  • Author(s): 田原康玄, 大澤春彦, 川本龍一, 名倉 潤, 三木哲郎, 牧野英一, 小原克彦
  • Organizer: 第51回日本糖尿病学会年次学術集会
  • Place of Presentation: 東京
• [Presentation] 体重に対する大腿筋量の相対的な低下と重心動揺 (2008)
  • Author(s): 田原康玄, 伊賀瀬道也, 城戸知子, 越智南美子, 三木哲郎, 小原克彦
  • Organizer: 第50回日本老年医学会学術集会・総会
  • Place of Presentation: 千葉
• [Presentation] 簡便な認知症診断システムの構築 (2008)
  • Author(s): 田口敬子, 田原康玄, 川尻真和, 伊賀瀬道也, 小原克彦, 三木哲郎
  • Organizer: 第50回日本老年医学会学術集会・総会
  • Place of Presentation: 千葉
• [Presentation] Urate anion exchanger gene, SLC22A12, polymorphism is associated with plasmauric acid levels but not inflammation and insulin resistance (2008)
  • Author(s): Tabara Y, Kawamoto R, Tachibana-Iimori R, Yamamoto M, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Plasma leptin levels and orthostatic hypertension in the elderly (2008)
  • Author(s): Tabara Y, Igase M, Tomoko K, Namiko O, Tetsuro M, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Composition of the lower extremity in relation to a high ankle-brachial index : The J-SHIPP study (2008)
  • Author(s): Tabara Y, Igase M, Kido T, Ochi N, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Orthostatic decline in augmentation index and late systolic blood pressure is a risk factor for silent lacunar infarction (2008)
  • Author(s): Tabara Y, Igase M, Nagai T, Kido T, Ochi N, Tetsuro M, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Association between metabolic syndrome and silent cerebral infarction (2008)
  • Author(s): Kido T, Tabara Y, Igase M, Nagai T, Ochi N, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Resistin, GFR and insulin resistance (2008)
  • Author(s): Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Reduced high-molecular weight adiponectin and elevated hsCRP are synergistic risk factors for metabolic syndrome in a large scale middle-aged to elderly population : The J-SHIPP study (2008)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Tachibana R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K
  • Organizer: 22nd Scientific Meeting, the International Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] Association between silent cerebral microbleeds and carotid arterial parameters in comparison with lacunar infarction and leukoaraiosis (2008)
  • Author(s): Ochi N, Tabara Y, Igase M, Nagai T, Kido T, Miki T, Kohara K.
  • Organizer: 22nd Scientific Meeting, the Internaticnal Society of Hypertension
  • Place of Presentation: Berlin, Germany
• [Presentation] CRP遺伝子多型と血中高感度CRP濃度ならびにメタボリックシンドロームとの相関 (2008)
  • Author(s): 田原康玄, 川本龍一, 山本美由紀, 森田昭彦, 中山智祥, 吉田安彦, 根本靖久, 三木哲郎, 小原克彦
  • Organizer: 第15回日本遺伝子診療学会大会
  • Place of Presentation: 仙台
• [Presentation] アディポネクチンとHDLコレステロールとの相関に対するCETP遺伝子多型の交互作用 (2008)
  • Author(s): 田原康玄, Haiyan Guo, 川本龍一, 山本美由紀, 小原克彦, 三木哲郎
  • Organizer: 第15回日本遺伝子診療学会大会
  • Place of Presentation: 仙台
• [Presentation] Nocturnal blood pressure and mild cognitive impairment in elderly (2008)
  • Author(s): Tabara Y, Igase M, Yamamoto M, Nakura J, Ochi N, Kido T, Miki T, Kohara K
  • Organizer: 62nd High Blood Pressure Research Conference
  • Place of Presentation: Atlanta, GA, USA
• [Presentation] 高脂血症感受性遺伝子多型の日本人一般地域住民における再現性の検討 (2008)
  • Author(s): 田原康玄, 川本龍一, 山本美由紀, 名倉 潤, 三木哲郎, 小原克彦
  • Organizer: 日本人類遺伝学会第53回大会
  • Place of Presentation: 横浜
• [Presentation] 無症候性微小脳出血と動脈硬化性因子との関連 (2008)
  • Author(s): 越智南美子, 田原康玄, 伊賀瀬道也, 永井勅久, 三木哲郎, 小原克彦
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
• [Presentation] 一般地域住民における軽度認知機能障害と血圧日内変動との相関 (2008)
  • Author(s): 田原康玄, 伊賀瀬道也, 山本美由紀, 名倉 潤, 越智南美子, 城戸知子, 三木哲郎, 小原克彦
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
• [Presentation] 下肢筋量と起立性血圧調節障害、ならびに動脈スティッフネスとの相関 (2008)
  • Author(s): 越智雅之, 田原康玄, 伊賀瀬道也, 越智南美子, 三木哲郎, 小原克彦
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
• [Book] 抗加齢ドックの実際-動脈硬化と闘うために- (2008)
  • Author(s): 三木哲郎, 伊賀瀬道也, 小原克彦, 田原康玄
  • Total Pages: 156
  • Publisher: メジカルビュー社