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Visceral Adiposity and lifestyle-related disease in Japanese middle-aged women.

Research Project

Project/Area Number 20390187
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionOsaka City University

Principal Investigator

HAYASHI Tomoshige  Osaka City University, 大学院・医学研究科, 准教授 (10381980)

Co-Investigator(Kenkyū-buntansha) ENDO Gingi  大阪市立大学, 大学院・医学研究科, 教授 (20160393)
SATO Kyoko  大阪市立大学, 大学院・医学研究科, 講師 (00381989)
HIKITA Yonezo  大阪市立大学, 大学院・医学研究科, 非常勤講師 (50420724)
Research Collaborator BOYKO Edward J.  ワシントン州立大学, 医学部, 教授
FUJIMOTO Wilfred Y.  ワシントン州立大学, 医学部, 名誉教授
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2010: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords疫学 / 内臓脂肪 / 生活習慣病 / 日系人 / コホート研究
Research Abstract

The study purpose of this study is to establish the prospective cohort study to examine the association between visceral adiposity measured by computed tomography (CT) and lifestyle-related diseases. We had enrolled 1647 men and women (1036 men and 611 women) since 2005. At this time, we had enrolled mainly women since 2008. In the multiple logistic regression models, visceral adiposity measured by CT was associated with an increased odd of the prevalence of impaired fasting glucose or type 2 diabetes, hypertension, hypertriglycemia, or low HDL cholesterol after adjustment for abdominal subcutaneous fat eara.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (56 results)

All 2011 2010 2009 2008

All Journal Article (16 results) (of which Peer Reviewed: 14 results) Presentation (37 results) Book (3 results)

  • [Journal Article] Visceral Adiposity, not Abdominal Subcutaneous Fat Area, Is Associated with the prevalence of hypertension : the Ohtori Study.2011

    • Author(s)
      Hayashi T (2番目/10), Sato KK (3番目/10), Endo G (7番目/10), Hikita Y (10番目/10)
    • Journal Title

      Hypertens Res. 34(5)

      Pages: 565-572

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Blood pressure components and risk for chronic kidney disease in middle-aged Japanese men : The Kansai Healthcare Study.2011

    • Author(s)
      Hayashi T (2番目/9), Sato KK (3番目/9), Endo G (7番目/9)
    • Journal Title

      Hypertens Res. 34(4)

      Pages: 536-541

    • NAID

      10031163213

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visceral adiposity, not abdominal subcutaneous fat area, is associated with high blood pressure in Japanese men.2011

    • Author(s)
      Hideo Koh
    • Journal Title

      Hypertension research

      Volume: 34 Pages: 565-572

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blood pressure components and risk for chronic kidney disease in middle-aged Japanese men.2011

    • Author(s)
      Hideo Koh
    • Journal Title

      Hypertension research

      Volume: 34 Pages: 536-541

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between drinking patterns and the risk of type 2 diabetes : the Kansai Healthcare Study.2010

    • Author(s)
      Sato KK (1番目/9), Hayashi T (2番目/9), Endo G (6番目/9)
    • Journal Title

      J Epidemiol Community Health. 3(Epub ahead of print)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fasting tests of insulin secretion and sensitivity predict future prediabetes in Japanese with normal glucose tolerance.2010

    • Author(s)
      Hayashi T (2番目/10), Sato KK (3番目/10)
    • Journal Title

      J Diabetes Invest. 1(5)

      Pages: 191-195

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between drinking patterns and the risk of type 2 diabetes2010

    • Author(s)
      Kyoko Sato
    • Journal Title

      Journal of epidemiology and community health

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The combined measurement of fasting plasma glucose and hemoglobin A1C is effective for the prediction of type 2 diabetes: The Kansai Healthcare Study.2009

    • Author(s)
      Sato KK (1番目/7), Hayashi T (2番目/7), Endo G (6番目/7)
    • Journal Title

      Diabetes Care. 32(4)

      Pages: 644-646

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low serum creatinine was associated with an increased risk of type 2 diabetes : The Kansai Healthcare Study.2009

    • Author(s)
      Hayashi T (2番目/7), Sato KK (3番目/7), Endo G (6番目/7)
    • Journal Title

      Diabetes Care. 32(3)

      Pages: 424-426

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low serum creatinine was associated with an increased risk of type 2 diabetes : The Kansai Healthcare Study.2009

    • Author(s)
      Harita, Nobuko
    • Journal Title

      Diabetes Care 32

      Pages: 424-426

    • Related Report
      2009 Annual Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 通勤時の歩行時間と糖尿病の関係は?2009

    • Author(s)
      佐藤恭子
    • Journal Title

      肥満と糖尿病 8

      Pages: 838-840

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 診断と治療社2009

    • Author(s)
      林朝茂
    • Journal Title

      糖尿病学2009:Visceral adiposityとmorbility:日系人糖尿病研究から

      Pages: 116-123

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Liver enzymes as compared with alcohol consumption in predicting the risk of type 2 diabetes : The Kansai Healthcare Study.2008

    • Author(s)
      Sato KK (1番目/7), Hayashi T (2番目/7), Endo G (6番目/7)
    • Journal Title

      Diabetes Care. 31

      Pages: 1230-1236

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visceral Adiposity, not Abdominal Subcutaneous Fat Area, Predicts Increased Future Insulin Resistance in Japanese Americans.2008

    • Author(s)
      Hayashi T (1番目/6)
    • Journal Title

      Diabetes. 57(5)

      Pages: 1269-1275

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visceral Adiposity, not Abdominal Subcutaneous Fat Area, Predicts Increased Future Insulin Resistance in Japanese Americans.2008

    • Author(s)
      Hayashi, Tomoshige
    • Journal Title

      Diabetes 57

      Pages: 1269-1275

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Liver enzymes as compared with alcohol consumption in predicting the risk of type 2 diabetes : The Kansai Healthcare Study.2008

    • Author(s)
      Sato, Kyoko
    • Journal Title

      Diabetes Care 31

      Pages: 1230-1236

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 血清アディポネクチンと腹部脂肪との関連性について2011

    • Author(s)
      佐藤恭子
    • Organizer
      第21回日本疫学会学術総会
    • Place of Presentation
      北海道
    • Year and Date
      2011-01-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清アディポネクチンと腹部脂肪との関連性について2011

    • Author(s)
      佐藤恭子
    • Organizer
      第21回日本疫学会学術総会
    • Place of Presentation
      北海道(かでる2.7)
    • Year and Date
      2011-01-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 推定糸球体濾過量と2型糖尿病新規発症の関連性2010

    • Author(s)
      佐藤恭子
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 腹部内臓脂肪と高トリグリセライド血症、低HDLコレステロール血症の関連について2010

    • Author(s)
      阪東千栄子
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 推定糸球体濾過量と2型糖尿病新規発症の関連性2010

    • Author(s)
      佐藤恭子
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山(ラヴィール岡山)
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 腹部内臓脂肪と高トリグリセライド血症、低HDLコレステロール血症の関連について2010

    • Author(s)
      阪東千栄子
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山(ラヴィール岡山)
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Higher Estimated Glomerular Filtration Rate Is a New Risk Factor of Type 2 Diabetes.2010

    • Author(s)
      佐藤恭子
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions.
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Independent Association of Adiponectin and Leptin with Both Abdominal Visceral and Subcutaneous Adiposity.2010

    • Author(s)
      佐藤恭子
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions.
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Late Phase Insulin Response during the Oral Glucose Tolerance Test Predicts Risk of Type 2 Diabetes.2010

    • Author(s)
      Tomoshige Hayashi
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions.
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Higher Estimated Glomerular Filtration Rate Is a New Risk Factor of Type 2 Diabetes2010

    • Author(s)
      Kyoko Sato
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Independent Association of Adiponectin and Leptin with Both Abdominal Visceral and Subcutaneous Adiposity2010

    • Author(s)
      Kyoko Sato
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Late Phase Insulin Response during the Oral Glucose Tolerance Test Predicts Risk of Type 2 Diabetes2010

    • Author(s)
      Tomoshige Hayashi
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions
    • Place of Presentation
      Orland (USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 腹部内臓脂肪・皮下脂肪と高血圧症の関係2009

    • Author(s)
      康秀男
    • Organizer
      第32回日本高血圧学会総会
    • Place of Presentation
      大津(滋賀)
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 腹部内臓脂肪・皮下脂肪と高血圧症の関係2009

    • Author(s)
      康秀男
    • Organizer
      第32回日本高血圧学会総会
    • Place of Presentation
      大津プリンスホテル(滋賀)
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] 飲酒パターンと2型糖尿病新規発症の関連について2009

    • Author(s)
      佐藤恭子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清クレアチニン値と2型糖尿病リスクの関係2009

    • Author(s)
      針田伸子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 正常型から境界型への進展の危険因子としてのインスリン分泌能低下2009

    • Author(s)
      大西由希子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 飲酒パターンと2型糖尿病新規発症の関連について2009

    • Author(s)
      佐藤恭子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 血清クレアチニン値と2型糖尿病リスクの関係2009

    • Author(s)
      針田伸子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 正常型から境界型への進展の危険因子としてのインスリン分泌能低下2009

    • Author(s)
      大西由希子
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 2型糖尿病発症の予測に対する空腹時血糖値とヘモグロビンA1c値の有用性2009

    • Author(s)
      佐藤恭子
    • Organizer
      第19回日本疫学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2009-01-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 2型糖尿病発症の予測に対する空腹時血糖値とヘモグロビンAle値の有用性2009

    • Author(s)
      佐藤恭子
    • Organizer
      第19回日本疫学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2009-01-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] Drinking Patterns Are the Important Risk Factor of the Incidence of Type 2 Diabetes.2009

    • Author(s)
      佐藤恭子
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions.
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Serum C-Reactive Protein Is Associated with Visceral but Not Abdominal Subcutaneous Adiposity.2009

    • Author(s)
      佐藤恭子
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Plasma Insulin Secretion Pattern during an OGTT Was Predictor of the Risk of Type 2 Diabetes.2009

    • Author(s)
      Tomoshige Hayashi
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Impaired Insulin Secretion Predicts Impaired Glucose Tolerance and/or Impaired Fasting Glucose.2009

    • Author(s)
      大西由希子
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] Drinking Patterns Are the Important Risk Factor of the Incidence of Type 2 Diabetes.2009

    • Author(s)
      Sato, Kyoko
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Serum C-Reactive Protein Is Associated with Visceral but Not Abdominal Subcutaneous Adiposity.2009

    • Author(s)
      Sato, Kyoko
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Plasma Insulin Secretion Pattern during an OGTT Was Predictor of the Risk of Type 2 Diabetes.2009

    • Author(s)
      Hayashi, Tomoshige
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Impaired Insulin Secretion Predicts Impaired Glucose Tolerance and/or Impaired Fasting Glucose.2009

    • Author(s)
      Onishi, Yukiko
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      New Orleans (USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 2型糖尿病発症のリスクに関する飲酒習慣と血清γ-GTPの関係2008

    • Author(s)
      佐藤恭子
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-24
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] The Combined Measurement of Fasting Plasma Glucose and Hemoglobin A1C was Effective for the Prediction of Type 2 Diabetes.2008

    • Author(s)
      佐藤恭子
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions.
    • Place of Presentation
      San Francisco
    • Related Report
      2010 Final Research Report
  • [Presentation] Serum Cholinesterase Is a New Predictor of Visceral Adiposity Independent of Fasting Plasma Insulin and Fatty Liver.2008

    • Author(s)
      佐藤恭子
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions.
    • Place of Presentation
      San Francisco
    • Related Report
      2010 Final Research Report
  • [Presentation] Which Simple Measure of Insulin Resistance is the Best Predictor of the Incidence of Type 2 Diabetes in Japanese Americans?2008

    • Author(s)
      Tomoshige Hayashi
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions.
    • Place of Presentation
      San Francisco
    • Related Report
      2010 Final Research Report
  • [Presentation] The Combined Measurement of Fasting Plasma Glucose and Hemoglobin A1C was Effective for the Prediction of Type 2 Diabetes2008

    • Author(s)
      Sato, Kyoko
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions
    • Place of Presentation
      San Francisco
    • Related Report
      2008 Annual Research Report
  • [Presentation] Serum Cholinesterase Is a New Predictor of Visceral Adiposity Independent of Fasting Plasma Insulin and Fatty Liver.2008

    • Author(s)
      Sato, Kyoko
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions
    • Place of Presentation
      San Francisco
    • Related Report
      2008 Annual Research Report
  • [Presentation] Which Simple Measure of Insulin Resistance is the Best Predictor of the Incidence of Type 2 Diabetes in Japanese Americans?2008

    • Author(s)
      Hayashi, Tomoshige
    • Organizer
      American Diabetes Association 68^<th> Scientific Sessions
    • Place of Presentation
      San Francisco
    • Related Report
      2008 Annual Research Report
  • [Book] 糖尿病学2010:空腹時血糖値とHbA_1c値による糖尿病の発症の予測-The Kansai Healthcare Studyから-2010

    • Author(s)
      佐藤恭子、林朝茂
    • Publisher
      診断と治療社
    • Related Report
      2010 Final Research Report
  • [Book] 糖尿病学2009:空腹時血糖値とHbA1c値による糖尿病の発症の予測-The Kansai Healthcare Studyから-2010

    • Author(s)
      佐藤恭子
    • Publisher
      診断と治療社
    • Related Report
      2010 Annual Research Report
  • [Book] 糖尿病学2009 : Visceral adiposityとmorbility:日系人糖尿病研究から2009

    • Author(s)
      林朝茂、他
    • Publisher
      診断と治療社
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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