Disturbance of innate immune system in alcoholic sudden death and organ damage
| Project/Area Number |
20390196
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Legal medicine
|
|---|
| Research Institution | Sapporo Medical University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2009: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
|
|---|
| Keywords | アルコール / Myd88 / TLR / 自然免疫 / 急死 / 壊死 / シグナリング / 大腿骨頭壊死 / 頭部外傷死 / トランスクリプトミクス / TLR4 |
|---|
| Research Abstract |
This study found that the transcription factor IRF7 and its-induced IFNalpha plays a crucial role in the alcohol-related death, traumatic brain injury under alcohol consumption, and osteonecrosis of the femoral head
|
Report
(4 results)
Research Products
(36 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Role of innate immune system of alcoholic liver disease and nonalcoholic fatty liver disease in forensic autopsy2009
Author(s)
Matsumoto H, Tanaka M, Fujii K, Nishitani Y, Katada R, Ishizaka A, Shimizu J, Igarashi A, Hagiwara T, Tateda K, Mizuo K, Watanabe S
Organizer
XXI Congress of the International Academy of Legal Medicine
Place of Presentation
Lisbon, Portugal
Related Report
-
-
-
-
-
