| Project/Area Number |
20390199
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Kagoshima University |
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Principal Investigator |
INUI Akio Kagoshima University, 医歯学総合研究科, 教授 (80168418)
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| Co-Investigator(Renkei-kenkyūsha) |
ANO Akira 鹿児島大学, 医歯学総合研究科, 教授 (30178800)
AMANAKA Hiroshi 鹿児島大学, 臨床心理学研究科, 教授 (60182581)
HOU De-Xing 鹿児島大学, 農学部, 准教授 (90305160)
HORIUCHI Masahisa 鹿児島大学, 歯学総合研究科, 准教授 (50264403)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2008: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
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| Keywords | 遺伝子 / 医療・福祉 / 神経医学 / トランスレーショナルリサーチ / 臨床 / 神経科学 |
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| Research Abstract |
The translational research was conducted on intractable nuero-metablic disorders such as congenital diseases including carnitine carrier deficiency, citrin deficiency and chorea acantosis, and maltifactorial diseases including cancer cachexia, eating disorders and mood disorders. JVS mouse and animal models of cancer cachexia and citrin deficiency were created and used on pathological analysis. New treatment methods, such as acetylcarnitine, pyruvic acid, ghrelin agonist and Rikkunshito, were created or applied clinically from this research work.
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