| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Research Abstract |
Direct or indirect interaction of oxygen-sensing voltage-gated potassium channel 1.5 (Kv1.5) with Kvb1.2, α actinin-2, SAP97, valosin containing protein, clathrin, HSP60, ATP synthase F1 α/βsubunits, α-actinin, prohibitin-1/-2was detected. These proteins might have roles in the cellular transportation and regulation of Kv1.5. Gene expression related to the storage of Ca2+in the sarcoplasmic reticulum (SR) in ductus arteriosus (DA) and pulmonary artery (PA) varied depending on the vessels and fetal developmental stages. The SR activity in the DA might be specific depending on the developmental stage.
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