Neuroimaging studies to investigate brain mechanisms of cognitive emotional interaction and the effects of abnormal interactions on psychiatric disorders
| Project/Area Number |
20390313
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Hiroshima University |
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Principal Investigator |
YAMAWAKI Shigeto Hiroshima University, 大学院・医歯薬学総合研究科, 教授 (40230601)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO Yasumasa 広島大学, 大学院・医歯薬学総合研究科, 講師 (70314763)
YAMASHITA Hidehisa 広島大学, 病院, 講師 (50294591)
OKADA Go 広島大学, 大学院・医歯薬学総合研究科, 特任助教 (10457286)
MANTANI Tomoyuki 広島大学, 病院, 講師 (70325174)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2010: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2009: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2008: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Keywords | 情動制御 / 認知機能 / うつ病 / 摂食障害 / 扁桃体 / 前頭前野 / 前帯状回 / MEG / 安静時fMRI / パーソナリティー特性 / 扁挑体 / 認知行動療法 / 前帶状回 / 心理的痛み / 自己関連ずけ / 身体イメージ / 情動・認知制御 / 情動予期 / 報酬予期 / 自己関連処理 / メタ分析 |
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| Research Abstract |
We conducted neuroimaging studies to investigate specific patterns of cognitive-emotional interaction and the underlying neurocircuitry in healthy controls and stress-related psychiatric disorders like depression and eating-disorders. The findings of our studies using various cognitive-emotional tasks and functional magnetic resonance imaging suggest that prefrontal and anterior cingulate cortex cognitively modulate emotional responses mediated by amygdala, and functional changes of these regions are present in stress-related psychiatric disorders.
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Report
(4 results)
Research Products
(40 results)
