| Project/Area Number |
20390338
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Akita University |
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Principal Investigator |
MINAMIYA Yoshihiro Akita University, 大学院・医学系研究科, 准教授 (30239321)
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| Co-Investigator(Kenkyū-buntansha) |
OGAWA Junichi 秋田大学, 大学院・医学系研究科, 教授 (20112774)
SAITO Hajime 秋田大学, 医学部, 講師 (20323149)
SAWADA Kenichi 秋田大学, 大学院・医学系研究科, 教授 (90226069)
多田 光宏 北海道大学, 遺伝子病制御研究所, 准教授 (10241316)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWAGUCHI Haruma 慶應義塾大学, 理工学部, 教授 (30051808)
UEDA Tomoaki 東京工業大学, 統合研究院, 教授 (50456258)
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| Research Collaborator |
II Tomoaki 慶應義塾大学, 理工学部・川口研究室, 学生
KOMORI Chiyo 秋田大学, 医学部附属病院・薬剤部, 研究員
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2008: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Keywords | ナノテクノロジー / 抗がん剤 / 機能性微粒子 / 癌 / 磁性体 / 高分子化合物 |
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| Research Abstract |
We developed functional nanoparticles, combined with thermo-sensitive polymers and magnetite. The functional nanoparticles emit heat when exposed to an AC magnetic field, causing them to release drugs. We have utilized these functional nanoparticles to administer methotrexate, an anti-cancer agent, making them ideal candidates for cancer thermo-chemotherapy.
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