| Co-Investigator(Kenkyū-buntansha) |
HATTA Takeshi 関西福祉科大学, 健康福祉学部, 教授 (80030469)
IMAGAMA Shirou 名古屋大学, 医学部附属病院, 助教 (40467288)
KANOU Toshiya 名古屋大学, 医学部附属病院, 医員 (10528813)
松山 幸弘 名古屋大学, 大学院・医学系研究科, 准教授 (20312316)
山口 仁 名古屋大学, 医学部附属病院, 医員 (00420381)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
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| Research Abstract |
Longitudinal and cross sectional epidemiological studies in orthopedic diseases for community living elderly people were investigated in Yakumo town. All participants with osteoarthritis(OA) of the knee(K-L 2=<) at the baseline developed further stage of OA at 10 year-follow-up. Radiographic knee OA was significantly presented on the left side in the cross sectional study. Physical exercise intervention group did not show any significant change in three month.
Participants with both knee OA and osteoporosis(YAM80%>) at baseline were significantly died than without knee OA or osteoporosis(OR=2. 30).
Genetic(SNP) analysis showed significant difference both knee OA and osteophyte formation of the spine. Serum carotenoid was significantly associated with knee OA, osteoporosis, and muscle strength.
Motor function was significantly associated with the locomotive syndrome.
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