Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2010: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2008: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
|
Research Abstract |
In order to clarify the roles of TGF-β/BMP signaling during angiogenesis in bone metastasis sites of breast cancer, we developed advanced in vivo optical imaging systems by which we can visualize tumor angiogenesis and TGF-β/BMP at the same time. In addition, we studied the effects of angiogenesis inhibitors and TGF-β/BMP signaling blockers during bone metastasis of breast cancer in vivo.
|