Translational research of animal study and clinical trial for the mechanisms of weather-dependent pain aggravation.
| Project/Area Number |
20390415
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagoya University |
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Principal Investigator |
SATO Jun Nagoya University, 環境医学研究所, 准教授 (00235350)
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| Co-Investigator(Kenkyū-buntansha) |
USHIDA Takahiro 愛知医科大学, 医学部, 教授 (60304680)
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| Co-Investigator(Renkei-kenkyūsha) |
SAKURAI Hiroki 浜松大学, 保健医療学部, 講師 (60454419)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2008: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
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| Keywords | 慢性疼痛 / 気象 / うつ病 / 自律神経 / 内耳前庭 / 慢性痛 / 大気圧 / うつ |
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| Research Abstract |
The authors have clarified underlying mechanisms of weather-sensitive diseases, such as chronic pain and depression in the basic animal research. In the present research project, we have further progressed the animal study and had clinical study using chronic pain patients with their pain to be sensitive to weather change. This translational study succeeded to product human model of weather-sensitive pain and provided a scientific link between laboratory research and human trials, and the beginning of discovery of therapeutic strategies for this syndrome.
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Report
(4 results)
Research Products
(53 results)
