| Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2010: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
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| Research Abstract |
The intraocular dynamics of VEGF plays a critical role in the pathogenesis of ischemic retinopathy including branch retinal vein occlusion. The long term suppression of intraocular VEGF levels proved important to maintain vision. In the experiments using mice, the role of inflammatory cells in the peripheral circulation was shown not to be essential for the formation of retinal neovascularization. Meanwhile, macrophages in the vitreous may be important in this aspect.
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