The influence of interactions between normal lymphatic endothelial cells and melanoma cells on cell migration
Project/Area Number |
20390455
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Plastic surgery
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Research Institution | Hokkaido University |
Principal Investigator |
OYAMA Akihiko (2009-2010) Hokkaido University, 北海道大学病院, 講師 (70374486)
堤田 新 (2008) Hokkaido University, 大学院・医学研究科, 講師 (00374489)
|
Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Yuhei 北海道大学, 大学院・医学研究科, 教授 (70271674)
FURUKAWA Hiroshi 北海道大学, 大学院・医学研究科, 講師 (00399924)
FUNAYAMA Emi 北海道大学, 大学院・医学研究科, 助教 (10533630)
HAYASHI Toshihiko 北海道大学, 北海道大学病院, 助教 (00432146)
SAITO Akira 北海道大学, 北海道大学病院, 医員 (70507574)
浜田 淳一 北海道大学, 遺伝子病制御研究所, 准教授 (50192703)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2010: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2009: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
|
Keywords | 悪性黒色腫 / 転移 |
Research Abstract |
Laminin-421 secreted by LEC possibly facilitates lymphatic metastasis through the induction of chemotaxis of melanoma cells.
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cells.2009
Author(s)
Saito N, Hamada J, Furukawa H, Tsutsumida A, Oyama A, Funayama E, Saito A, Tsuji T, Tada M, Moriuchi T, Yamamoto Y.
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Journal Title
Pigment Cell Melanoma Res. 22
Pages: 601-10
Related Report
Peer Reviewed
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