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Titanium implant surface modification and tissue regeneration by phosphorylated pullulan

Research Project

Project/Area Number 20390498
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionOkayama University

Principal Investigator

SUZUKI Kazuomi  Okayama University, 大学院・医歯薬学総合研究科, 教授 (30050058)

Co-Investigator(Kenkyū-buntansha) IRIE Masao  岡山大学, 大学院・医歯薬学総合研究科, 助教 (90105594)
TANAKA Jiro  岡山大学, 大学院・医歯薬学総合研究科, 助教 (40171764)
Co-Investigator(Renkei-kenkyūsha) YAMAMOTO Toshio  岡山大学, 大学院・医歯薬学総合研究科, 教授 (30107776)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2009: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2008: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Keywordsインプラント / チタン / 表面処理 / 骨伝導 / 上部構造体 / 適合性 / 接着材 / 被膜強さ / 被膜厚さ
Research Abstract

The improvement of bone formation-inducing activity for dental implant treatment and the newly developed adhesive for superstructure (crown, bridge, etc) were investigated. At 2 weeks after the implant surgery in rat tibia, the enhanced new bone formation was showed on the titanium surface treated with phosphorylated pullulan. The bone strength to Ag-Au-Pt-Cu alloys of 15-20% derivatized amino acid (cystine) containing urethane dimethacrylate polymers was 22.4MPa(SD:1.8),and the degradation of the bone strength was only 10% after thermal cycling with 20.000 cycles at 5-55℃.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (16 results)

All 2011 2010 2009 2008

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (4 results)

  • [Journal Article] Determinants of early interfacial-gap performance of indirect composite restoration.2010

    • Author(s)
      Irie, M., Maruo, Y., Nishigawa, G., Suzuki, K., Watts, D.C.
    • Journal Title

      Dental Materials 26

      Pages: 608-615

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nano-controlled molecular interaction at adhesive interfaces for hard-tissue reconstruction.2010

    • Author(s)
      Yoshohara, K., Yoshida, Y., Nagaoka, N., Fukegawa, D., Hayakawa, S., Mine, A., Nakamura, M., Minagi, S., Osaka, A., Suzuki, K., van Meerbeek, B.
    • Journal Title

      Acta Biomaterialia 6

      Pages: 3573-3582

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanical properties of resin-modified glass ionomer cements for luting : Effect of adding spherical silica filler.2010

    • Author(s)
      Lihua, E., Irie, M., Nagaoka, N., Yamashiro, T., Suzuki, K.
    • Journal Title

      Dental Materials Journal 29

      Pages: 253-261

    • NAID

      10026470095

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determinants of early interfacial-gap performance of Indirect composite restorations.2010

    • Author(s)
      Irie, M., Suzuki, K., et al
    • Journal Title

      Dental Materials

      Volume: 26 Pages: 608-615

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nano-controlled molecular interaction at adhesive interfaces for hard tissue reconstruction2010

    • Author(s)
      Yoshihara, K., Suzuki, K., et al.
    • Journal Title

      Acta Biomaterialia

      Volume: 6 Pages: 3573-3582

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanical properties of Resin-modified glass ionomer cements for luting2010

    • Author(s)
      Lihua, E., Suzuki, K., et al.
    • Journal Title

      Dental Materials Journal

      Volume: 29 Pages: 253-261

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Delayed polishing technique on glass-ionomer restorations.2009

    • Author(s)
      Irie, M., Suzuki, K., Watts, D.C.
    • Journal Title

      The Japanese Dental Science Review 45

      Pages: 14-22

    • NAID

      10025820344

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial effect of bactericide immobilized in resin matrix.2009

    • Author(s)
      Nanba, N., Yoshida, Y., Nagaoka, N., Takashiba, S., Matsuura-Yoshimoto, K., Maeda, H., Van Meerbeek, B., Suzuki, K.
    • Journal Title

      Dental Materials 25

      Pages: 424-430

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Delayed polishing technique on glass-ionomer restorations.2009

    • Author(s)
      Irie, M., Suzuki, S., et al.
    • Journal Title

      The Japanese Dental Science Review 45

      Pages: 14-22

    • NAID

      10025820344

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial effect of bactericide immobilized in resin matrix.2009

    • Author(s)
      Nanba, N., Suzuki, S., et al.
    • Journal Title

      Dental Materials 45

      Pages: 424-430

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flexral performance of flowable versus conventional light-cured composite resin in long-term in vitro study.2008

    • Author(s)
      Irie, M., Tjandrawinata, R., Lihua, E., Suzuki, K.
    • Journal Title

      Dental Materials Journal 27

      Pages: 300-309

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fiexral Performance of Flowable versus Conventional Light-cured Composite Resins in a Long-term in vitro Study2008

    • Author(s)
      Irie, M., et al.
    • Journal Title

      Dental Materials Journal 27

      Pages: 300-309

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Early no interfacial-gap incidence vs. Flexual Modulus with injectable composites2011

    • Author(s)
      Irie, M., Tamada, Y., Maruo, Y., Nishigawa, G., Oka, M., Minagi, S., Suzuki K., Watts, D.C.
    • Organizer
      Annual Meeting of the IADR
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-19
    • Related Report
      2010 Final Research Report
  • [Presentation] Early No Interfacial-Gap Incidence vs.Flexural Modulus with Injectable Composites2011

    • Author(s)
      Masao Irie
    • Organizer
      International Association for Dental Research
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2011-03-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 接着界面の最前線:界面の形成メカニズムと機能について2010

    • Author(s)
      鈴木一臣
    • Organizer
      第28回日本接着歯学会学術大会(招待講演)
    • Place of Presentation
      松江市くにびきメッセ
    • Year and Date
      2010-01-23
    • Related Report
      2010 Final Research Report
  • [Presentation] 接着界面の最前線 : 界面の形成メカニズムと機能について2010

    • Author(s)
      鈴木一臣
    • Organizer
      第28回 日本接着歯学会学術大会
    • Place of Presentation
      松江市くにびきメッセ
    • Year and Date
      2010-01-23
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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