Development of a light cured resin-BMP composite material intending to induce new bone formation in vivo
| Project/Area Number |
20390502
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TSURUTA Shozou 愛知学院大学, 歯学部, 准教授 (40183488)
HAYASHI Tatsuhide 愛知学院大学, 歯学部, 講師 (70367621)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2010: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2008: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
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| Keywords | 生体材料 / 生物・生体工学 / 再生医療 / 光造形 / biomaterial / tissue engineering / biological engineering / 3D modeling / バイオテクノロジー |
|---|
| Research Abstract |
In order to develop an implant material that has a potential to induce new bone formation adequate to the 3-dimentional shape that refrects to each clinical situation, a resin with BMP composite was assembled. According to the 3-Dimentional data obtaining from micro X-ray CT system, resin scaffold was made by means of 3D-SLS system, then combined with BMP. The composite material was implanted in vivo and new bone formation occurred surrounding tissue of the scaffold.
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Report
(4 results)
Research Products
(52 results)
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[Journal Article] Development of an orthodontic elastic material using EMA-based resin combined with 1-butanol2011
Author(s)
Masuda, T., Miyazawa, K., Ueda, N., Hata, Y., Kawai, T., Goto, S
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Journal Title
Dental Materials Journal
Volume: 30(5)
Pages: 664-671
NAID
Related Report
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[Journal Article] In vitro biocompatibility of dextrin : the addition of a low-concentration of dextrin in the medium promotes the cell activity of L929 mouse fibroblasts2011
Author(s)
Asai, T., Hayashi, T., Kuroki, K., Okano, M., Kiriyama, T., Kawai, T
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Journal Title
Cell Biology International
Volume: 35
Pages: 645-648
Related Report
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[Journal Article] Fundamental research on the mechanical properties of resin products using selective laser sintering molding2010
Author(s)
Iseda, A., Ishikawa, A., Kawai, T., Sato, Y., Abe, A., Hamajima, S., Asakura, M., Mi zuno, T., Murakami, H., Hattori, M
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Journal Title
Aichi Gakuin Dent Sci
Volume: 23
Pages: 1-8
NAID
Related Report
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[Journal Article] Human acid-insoluble dentin with BMP-2 accelerates bone induction in subcutaneous and intramuscular tissues2010
Author(s)
Murata, M., Kawai, T., Kawakami, T., Akazawa, T., Tazaki, J., Ito, K., Kusano, K., Arisue, M
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Journal Title
Journal of the Ceramic Society of Japan
Volume: 118(6)
Pages: 438-441
NAID
Related Report
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[Presentation] Osteoinductive activity of BMP-Metal composite material2011
Author(s)
Ueda, N., Kawai, T., Hayashi, T., Tsuruta, S., Taniyama, M., Hamajima, S., Sato, Y., Kobayashi, S., Ohno, Y., Uematsu, Y
Organizer
The international dental materials congress 2011
Place of Presentation
seoul
Year and Date
2011-05-29
Related Report
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[Presentation] Bone-like tissue induced by rhBMPs in vitro has Ossification potential in vitro2011
Author(s)
Hayashi, T., Asai, T., Asakura, M., Sasaki, K., Uematsu, Y., Mieki, A., Kataoka, H., Kawai, T
Organizer
The international dental materials congress 2011
Place of Presentation
seoul
Year and Date
2011-05-29
Related Report
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[Presentation] The Basic experiment about the effective of sintered titanium dioxide as a bone filling material2011
Author(s)
Asai, T., Hayashi, T., Kuroki, K., Mieki, A., Kataoka, H., Kawai, T
Organizer
The international dental materials congress 2011
Place of Presentation
seoul
Year and Date
2011-05-28
Related Report
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[Presentation] Surface analysis of titanium influenced by plasma glow discharge2011
Author(s)
Muraji, N., Iwata, T., Kawai, T., Ueda, N., Miyazawa, K., Goto, S., Tanaka, Y
Organizer
The international dental materials congress 2011
Place of Presentation
seoul
Year and Date
2011-05-28
Related Report
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[Presentation] Application of Dextrin as a crude BMP Carrier2010
Author(s)
Asai, T., Hayashi, T., Mieki, A., Kataoka, H., Hamajima, S., Kiriyama, T., Kawai, T
Organizer
IADR 88th General Session Exhibition of IADR
Place of Presentation
Barecelona
Year and Date
2010-07-15
Related Report
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[Presentation] rhBMPs induce immature muscular tissue to differentiate into bone-like tissue2010
Author(s)
Hayashi, T., Asai, T., Mieki, A., Kataoka, H, Hamajima, S., Sato, Y., Asakura, M., Kawai, T
Organizer
88th General Session & Exhibition of IADR
Place of Presentation
Barecelona
Related Report
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