| Project/Area Number |
20390550
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical nursing
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| Research Institution | Gunma University |
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Principal Investigator |
KANDA Kiyoko 群馬大学, 大学院・保健学研究科, 教授 (40134291)
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| Co-Investigator(Kenkyū-buntansha) |
FUTAWATARI Tamae 群馬大学, 大学院・保健学研究科, 教授 (00143206)
TAKEI Akemi 群馬大学, 大学院・保健学研究科, 助教 (70431715)
HORIKOSHI Masataka 群馬大学, 大学院・保健学研究科, 助教 (80451722)
OBATA Hidaaki 群馬大学, 医学部, 講師 (20302482)
TUTUMI Souiti 群馬大学, 医学系研究科, 助教 (30323356)
SEYAMA Ruka 東京慈恵会医科大学, 医学部, 講師 (10412991)
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2008: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
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| Keywords | 抗がん剤 / 持続性末梢神経障害 / 大腸がん / オキサリプラチン / 質的研究 / 神経伝達速度 / 評価指標 / がん化学療法 / 体験 / 末梢神経障害 / Oxaliplatin / エルプラット / アセスメント指標 / 主観評価 / 客観指標 / 自律の体験 / FOLFOX療法 |
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| Research Abstract |
We performed a survey to compile assessment indicators for accurate identification of the severity and effects of peripheral neuropathy in colorectal cancer patients on ambulatory chemotherapy, with the ultimate aim of developing a comprehensive care model. To compile the indicators we conducted interviews and measurements to clarify the extent of neuropathy and its impact on daily activities and mental and social status. For neurological responses there was no statistical significance, so we considered neurological measurement to be inappropriate for evaluation. The qualitative part of the study revealed that neuropathy was a far-reaching disorder that affected sexual life and caused emotional distress. The results suggested that the assessment indicators for neuropathy should include numbness, physical symptoms, and effects on everyday life and social activities, so that the patient's neuropathy can be evaluated as a far-reaching disorder with effects on both body and mind. The results also suggested that a comprehensive care model is needed.
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