Field Study on natural medicinal resources in Bangladesh

• Project/Area Number: 20404004
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Living organism molecular science
• Research Institution: Chiba University
• Principal Investigator: ISHIBASHI Masami 千葉大学, 大学院・薬学研究院, 教授 (90212927)
• Co-Investigator(Kenkyū-buntansha): ARAI Midori 千葉大学, 大学院・薬学研究院, 准教授 (40373261) ; OHSAKI Ayumi 東京医科歯科大学, 生体材料工学研究所, 助教 (50161360) ; OHTSUKI Takashi 千葉大学, 大学院・薬学研究院, 助教 (30401011) ; TOUME Kazufumi 千葉大学, 大学院・薬学研究院, 助教 (80563981)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000); Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2008: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
• Keywords: 天然物化学 / 資源調査 / スクリーニング / 熱帯植物 / 天然物 / 薬学 / バングラデシュ / ライブラリー構築 / アッセイ / 創薬資源

Research Abstract

In 2008-2011 the representative of this research project (Masami Ishibashi) visited Bangladesh every year and investigated field-study on natural medicinal resources in Bangladesh mainly on tropical plants. As a result, approximately nearly 200 kinds of plant species were collected, and they were mainly field-characteristic plant species as well as locally cultivated medical herbs. Extracts of these plant materials were subjected to screening tests against signaling pathways such as Wnt, hedgehog, and TRAIL, and from active samples several new bioactive natural products were isolated.

Research Products

• [Journal Article] Phorbol esters with Wnt signal-augmentingeffects isolated from Excoecaria indica (2012)
  • Author(s): Yamaguchi, T., Toume, K., Arai, M. A., Ahmed, F., Sadhu, S. K., Ishibashi, M.
  • Journal Title: Nat.Prod. Commun Volume: 7 Pages: 475-477
• [Journal Article] A new resin glycoside from Ipomoea maxima (2012)
  • Author(s): Koryudzu, K., Arai, M. A., Ahmed, F., Sadhu, S. K., Ishibashi, M.
  • Journal Title: Nat. Prod.Commun Volume: 7 Pages: 219-220
• [Journal Article] Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinomacells to TRAIL-induced apoptosis (2011)
  • Author(s): Ahmed, F., Toume, K., Ohtsuki, T., Rahman, M., Sadhu, S. K., Ishibashi, M.
  • Journal Title: Phytotherapy Research Volume: 25 Pages: 147-150
• [Journal Article] New Hedgehog/GLI signaling inhibitors from Excoecariaagallocha (2011)
  • Author(s): Rifai, Y., Arai, M. A., Sadhu, S. K., Ahmed, F., Ishibashi, M.
  • Journal Title: Bioorg. Med. Chem. Lett Volume: 21 Pages: 718-722
• [Journal Article] Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis (2011)
  • Author(s): Ahmed, F., Toume, K., Ohtsuki, T., Rahman, M., Sadhu, S.K., Ishibashi, M.
  • Journal Title: Phytotherapy Research 25 Pages: 147-150
  • Peer Reviewed
• [Journal Article] New Hedgehog/GLI signaling inhibitors from Excoecaria agallocha (2011)
  • Author(s): Rifai, Y., Arai, M.A., Sadhu, S.K., Ahmed, F., Ishibashi, M.
  • Journal Title: Bioorg.Med.Chem.Lett. 21 Pages: 718-722
  • Peer Reviewed
• [Journal Article] New Hedgehog/GLI signaling inhibitors from Excoecaria agallocha (2011)
  • Author(s): Yusnita Rifai
  • Journal Title: Bioorganic and Medicinal ChemistryLetters Volume: 21 Pages: 718-722
  • Peer Reviewed
• [Journal Article] Glycosides from Vallaris solanaceae with TRAIL-resistance overcoming activity (2010)
  • Author(s): Ahmed, F., Sadhu, S. K., Ohtsuki, T., Khatun, A., Ishibashi, M.
  • Journal Title: Heterocycles Volume: 80 Pages: 477-488
  • NAID: 40016900121
• [Journal Article] Cucullamide, anew putrescine bisamide from Amooracucullata (2010)
  • Author(s): Abdelfattah, M. S., Toume, K., Ahmed, F., Sadhu, S. K., Ishibashi, M.
  • Journal Title: Chem. Pharm. Bull Volume: 58 Pages: 1116-1118
• [Journal Article] Constituents of Amoora cucullata with TRAIL resistance overcoming activity (2010)
  • Author(s): Ahmed, F., Toume, K., Sadhu, S. K.;, Ohtsuki, T., Arai, M. A., Ishibashi, M.
  • Journal Title: Org.Biomol. Chem Volume: 8 Pages: 3696-3703
• [Journal Article] Constituents of Pongamia pinnata isolatedin a screening for activity to overcome TRAIL-resistance (2010)
  • Author(s): Minakawa, T., Toume, K., Ahmed, F., Sadhu, S. K., Ohtsuki, T., Arai, M. A., Ishibashi, M.
  • Journal Title: Chem. Pharm. Bull Volume: 58 Pages: 1549-1551
• [Journal Article] Search for bioactive natural products from medicinal plants of Bangladesh (2010)
  • Author(s): Ahmed, F., Sadhu, S. K., Ishibashi, M.
  • Journal Title: J. Nat. Med Volume: 64 Pages: 393-401
  • NAID: 10027710270
• [Journal Article] Search for bioactive natural products from medicinal plants of Bangladesh (2010)
  • Author(s): Ahmed, F., Sadhu, S.K., Ishibashi, M.
  • Journal Title: J.Nat.Med. 64 Pages: 393-401
  • NAID: 10027710270
  • Peer Reviewed
• [Journal Article] Glycosides from Vallaris solanaceae with TRAIL-resistance-overcoming activity (2010)
  • Author(s): Ahmed, F., Sadhu, S.K., Ohtsuki, T., Khatun, A., Ishibashi, M.
  • Journal Title: Heterocycles 80 Pages: 477-488
  • NAID: 40016900121
  • Peer Reviewed
• [Journal Article] Constituents of Amoora cucullata with TRAIL resistance overcoming activity (2010)
  • Author(s): Ahmed, F., Toume, K., Sadhu, S.K., Ohtsuki, T., Arai, M.A., Ishibashi, M.
  • Journal Title: Org.Biomol.Chem. 8 Pages: 3696-3703
  • Peer Reviewed
• [Journal Article] Constituents of Pongamia pinnata isolated in a screening for activity to overcome TRAIL-resistance (2010)
  • Author(s): Minakawa, T., Toume, K., Ahmed, F., Sadhu, S.K., Ohtsuki, T., Arai, M.A., Ishibashi, M.
  • Journal Title: Chem.Pharm.Bull. 58 Pages: 1549-1551
  • Peer Reviewed
• [Journal Article] Glycosides from Vallaris solanaceae with TRAIL-resistance-overcoming activity (2010)
  • Author(s): Ahmed Firoj
  • Journal Title: Heterocycles Volume: 80 Pages: 477-488
  • Peer Reviewed
• [Journal Article] Constituents of Amoora cucullata with TRAIL resistance overcoming activity (2010)
  • Author(s): Ahmed Firoj
  • Journal Title: Organic and Biomolecular Chemistry Volume: 8 Pages: 3696-3703
  • Peer Reviewed
• [Journal Article] Structure of new monoterpene glycoside from Sibiraeaangustata Rchd. and its anti-obestic effect (2009)
  • Author(s): Ito, Y., Kamo, S., Sadhu, S. K., Ohtsuki, T., Ishibashi, M., Kano, Y.
  • Journal Title: Chem. Pharm. Bull Volume: 57 Pages: 294-297
  • NAID: 110007122353
• [Journal Article] Cadinane sesquiterpenes from Curcuma parviflora (2009)
  • Author(s): Sadhu, S. K., Tamaki, M., Ohtsuki, T., Toume, K., Koyano, T., Kowithayakorn, T., Ishibashi, M.
  • Journal Title: J. Nat. Prod Volume: 72 Pages: 782-783
• [Journal Article] Two new cadinane sesquiterpenes from Curcuma parviflora. (2009)
  • Author(s): S.K.Sadhu
  • Journal Title: Journal of Natural Products 72 Pages: 782-783
  • Peer Reviewed
• [Journal Article] Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRIL-induced apoptosis. (2009)
  • Author(s): T.Ohtsuki
  • Journal Title: Bioorganic Medicinal Chemistry 17 Pages: 6748-6754
  • Peer Reviewed
• [Journal Article] Cardenolide glycosides of Thevetia peruviana and triterpenoid saponins of Sapindus emarginatus as TRAIL resistance-overcoming compounds (2009)
  • Author(s): T.Miyagawa
  • Journal Title: Journal of Natural Products 72 Pages: 1507-1511
  • Peer Reviewed
• [Journal Article] Constituents from Hoya parasitica and their cell growth inhibitory activity (2008)
  • Author(s): Sadhu, S. K., Khatun, A., Ohtsuki, T.;, Ishibashi, M.
  • Journal Title: Planta Medica Volume: 74 Pages: 760-763
• [Journal Article] Constituents from Hoya parasitica and their cell growth inhibitory activity (2008)
  • Author(s): Sadhu, S.K., Khatun, A., Ohtsuki, T., Ishibashi, M.
  • Journal Title: Planta Medica 74 Pages: 760-763
  • Peer Reviewed
• [Journal Article] Constituents from Hoya parasitica and their cell growth inhibitor activity (2008)
  • Author(s): S. K. Sadhu
  • Journal Title: Planta Medica 74 Pages: 760-763
  • Peer Reviewed
• [Journal Article] Acylated triterpenoid saponins from Schima noronhae and their cell growth inhibitory activity (2008)
  • Author(s): T. Ohtsuki
  • Journal Title: J. Nat. Prod. 71 Pages: 918-921
  • Peer Reviewed
• [Journal Article] Tyrosine derivatives isolated from Streptomyces sp. IFM lO937 in a screening program for TRAIL-resistance overcoming activity (2008)
  • Author(s): F. Ahmed
  • Journal Title: J. Nat. Prod. 71 Pages: 1963-1966
  • Peer Reviewed
• [Presentation] Calotropis giganteaからのWntシグナル阻害作用をもつ天然物の探索 (2012)
  • Author(s): 朴賢英, 當銘一文, 荒井緑, S.K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 札幌
• [Presentation] Derris indica等からのデス受容体誘導作用をもつ天然物の探索 (2012)
  • Author(s): T. Hoque, 當銘一文, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 札幌
• [Presentation] Phenolic compounds from the bark of Oroxylum indicum that enhcance Ngn2 promoter activity (2012)
  • Author(s): R. Fuentes, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 札幌
• [Presentation] Wntシグナル阻害作用をもつXylocarpus granatum由来の新規リモノイド (2012)
  • Author(s): 神谷謙太朗, 當銘一文, S. K. Sadhu, F. Ahmed, 荒井緑, 石橋正己
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 札幌
• [Presentation] ヘッジホッグシグナルを阻害するAcacia pennata とExcoecariaagallochaの成分 (2011)
  • Author(s): Y. Rifai, 荒井緑, 小谷野喬, T. Kowithayakorn, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 第55回香料・テルペンおよび精油化学に関する討論会
  • Place of Presentation: 筑波
• [Presentation] Asparagus racemosusの成分探索 (2011)
  • Author(s): 小宮山哲平, 小沢正晃, 岸田晶夫, S. K. Sadhu, F. Ahmed, 大崎愛弓, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Studies on bioactive constituents isolated from Bangladeshi mangrove Rhizophora mucronata (2011)
  • Author(s): 大崎愛弓, 谷口香織, 岸田晶夫, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Calotropis giganteaからのWntシグナル阻害作用をもつ天然物の探索 (2011)
  • Author(s): 朴賢英, 當銘一文, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Search for bioactive constituents from Derris indica with DR5 promoter activity (2011)
  • Author(s): Hoque Tahmina, 當銘一文, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Xylocarpus granatum からのWnt シグナル阻害作用をもつ天然物の探索 (2011)
  • Author(s): 神谷謙太朗, 森直美, 當銘一文, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Kandelia candelからのTRAIL耐性克服作用を有する天然物の探索 (2011)
  • Author(s): 皆川朋皓, 當銘一文, 荒井緑, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本生薬学会第58年会
  • Place of Presentation: 東京
• [Presentation] Kandelia candelからのTRAIL耐性克服作用を有する天然物の探索 (2011)
  • Author(s): 皆川朋皓, 當銘一文, F. Ahmed, S. K. Sadhu, 荒井緑, 石橋正己
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡
• [Presentation] Vitex negundoからのヘッジホッグ伝達経路阻害剤の探索 (2011)
  • Author(s): 荒井緑, 藤松輝久, A. K. Paul, F. Ahemd, S. K. Sadhu, 石橋正己
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡
• [Presentation] Xylocarpus granatum からのWntシグナル阻害作用をもつ天然物の探索 (2011)
  • Author(s): 神谷謙太朗, 森直美, 當銘一文, S. K. Sadhu, F. Ahmed, 荒井緑, 石橋正己
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡
• [Presentation] バングラデシュ産薬用植物の生物活性成分の探索 (2011)
  • Author(s): 大崎愛弓, 小沢正晃, 谷口香織, 岸田晶夫, S. K. Sadhu, 石橋正己
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡
• [Presentation] Cynometra ramiflora からのデスレセプター誘導作用を有する天然物の探索 (2011)
  • Author(s): 當銘一文, D. Kurnia, T. Hoque, S. K. Sadhu, F. Ahmed, 荒井緑, 石橋正己
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡
• [Presentation] The search for bioactive compounds from medicinal plants of Bangladesh regarding anti-cancer properties (2010)
  • Author(s): A. Ohsaki, M. Ozawa, K. Taniguchi, A. Kishida, F. Ahmed, S. K. Sadhu, M. Ishibashi
  • Organizer: Pacifichem
  • Place of Presentation: Honolulu, U.S.A
  • Year and Date: 2010-12-18
• [Presentation] Search for bioactive natural products targeting TRAIL signaling for tumor-selective apoptosis inducement (2010)
  • Author(s): M. Ishibashi
  • Organizer: Pacifichem
  • Place of Presentation: Honolulu, U.S.A
  • Year and Date: 2010-12-17
• [Presentation] がん選択的アポトーシス誘導作用をもつ天然物の探索 (2010)
  • Author(s): 石橋正己
  • Organizer: ミニシンポジウム-天然物化学の新展開(高知)
  • Place of Presentation: 高知大学
  • Year and Date: 2010-11-26
• [Presentation] TRAIL-resistance overcoming constituents from a mangrove Amoora cucullata (2010)
  • Author(s): K.Toume, F.Ahmed, T.Ohtsuki, S.K.Sadhu, M.A.Arai, M.Ishibashi
  • Organizer: 13th International Symposium on Marine Natural Products
  • Place of Presentation: Phuket
  • Year and Date: 2010-10-19
• [Presentation] Vitex negundoからのヘッジホッグシグナル伝達経路阻害剤の探索 (2010)
  • Author(s): 荒井緑, 藤松輝久, A. K. Paul, F. Ahmed, S. K. Sadhu, 石橋正己
  • Organizer: 第54回日本薬学会関東支部大会
  • Place of Presentation: 八王子
  • Year and Date: 2010-10-02
• [Presentation] TRAILシグナルを介してがん選択的にアポトーシスを誘導する天然物の探索 (2010)
  • Author(s): 當銘一文, F.Ahmed, 中澤孝文, 大槻崇, 荒井緑, 石橋正己
  • Organizer: 第52回天然有機化合物討論会
  • Place of Presentation: 静岡
  • Year and Date: 2010-09-29
• [Presentation] Constituents of Amoora cucullata with TRAIL resistance overcoming activity (2010)
  • Author(s): F.Ahmed, K.Toume, S.K.Sadhu, T.Ohtsuki, M.A.Arai, M.Ishibashi
  • Organizer: 日本生薬学会第57年会
  • Place of Presentation: 徳島
  • Year and Date: 2010-09-26
• [Presentation] Hedgehog/GLI Signaling Inhibitors from Acacia pennata and Excoecariaag allocha (2010)
  • Author(s): Y. Rifai, M. A. Arai, S. K. Sadhu, T. Koyano, T. Kowithayakorn, M. Ishibashi
  • Organizer: 第18回天然薬物の開発と応用シンポジウム
  • Place of Presentation: 東京
• [Presentation] バングラデシュ産薬用植物Asparagus racemosusの成分探索および生理活性評価 (2010)
  • Author(s): 小沢正晃, 岸田晶夫, S. K. Sadhu, 大崎愛弓, 石橋正己
  • Organizer: 第54回香料・テルペンおよび精油化学に関する討論会
  • Place of Presentation: 甲府
• [Presentation] バングラデシュ産薬用植物R hizophora mucronataの成分 (2010)
  • Author(s): 谷口香織, 小沢正晃, 岸田晶夫, S. K. Sadhu, 大崎愛弓, 石橋正己
  • Organizer: 第54回香料・テルペンおよび精油化学に関する討論会
  • Place of Presentation: 甲府
• [Presentation] ウィントシグナルに作用する天然物:タイおよびバングラデシュ植物のスクリーニング (2010)
  • Author(s): 石橋正己, 山口達弘, 森直美, 李暁帆, 當銘一文, 荒井緑, 小谷野喬, T. Kowithayakorn, S. K. Sadhu
  • Organizer: 第54回香料・テルペンおよび精油化学に関する討論会
  • Place of Presentation: 甲府
• [Presentation] TRAIL-resistance overcoming constituents from a mangrove Amoora cucullata (2010)
  • Author(s): K. Toume, F. Ahmed, T. Ohtsuki, S. K. Sadhu, M. A. Arai, M. Ishibashi
  • Organizer: 13th International Symposium on Marine Natural Products (MaNaPro XIII)
  • Place of Presentation: Phuket
• [Presentation] Isolation of flavonoids with TRAIL resistance-overcoming ctivity from Pngamia pinnata (2010)
  • Author(s): T. Minakawa, K. Toume, F. Ahmed, S. K. Sadhu, T. Ohtsuki, M. A. Arai, M. Ishibashi
  • Organizer: 13th International Symposium on MarineNatural Products (MaNaPro XIII)
  • Place of Presentation: Phuket
• [Presentation] Constituents of Amoora cucullata with TRAIL resistance overcoming activity (2010)
  • Author(s): F. Ahmed, K. Toume, S. K. Sadhu, T. Ohtsuki, M. A. Arai, M. Ishibashi
  • Organizer: 日本生薬学会
  • Place of Presentation: 徳島
• [Presentation] Hedgehog/GLI-mediated transcriptional inhibitors fromAcacia pennata and Exocoecaria agallocha (2010)
  • Author(s): Y. Rifai, 荒井緑, 小谷野喬, T. Kowithayakorn, S. K. Sadhu, F. Ahmed, 石橋正己
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山
• [Presentation] 神経幹細胞で働く転写因子Hes1を標的とした活性天然物の探索 (2010)
  • Author(s): 荒井緑, 伊藤友紀, 小柳津和音, 大塚俊之, 影山龍一郎, Alok K. Paul, FirojAhmed, Samir K. Sadhu, 石橋正己
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山
• [Presentation] 神経幹細胞の分化促進作用をもつ天然物,天然物様化合物の探索 (2010)
  • Author(s): 前川雄一, 荒井緑, 柳瀬なつき, F. Ahmed, S. K. Sadhu, 石橋正己
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山
• [Presentation] Pongamia pinnata からのTRAIL耐性克服作用を有する天然物の探索 (2010)
  • Author(s): 皆川朋皓, 當銘一文, F. Ahmed, S. K. Sadhu, 大槻崇, 石橋正己
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山
• [Presentation] Semecarpus anacardium 等からのヘッジホッグシグナル伝達経路阻害作用をもつ天然物の探索 (2010)
  • Author(s): 荒井緑, 藤松輝久, M. S. K. Choudhury, A. K. Paul, F. Ahmed, S. K. Sadhu,石橋正己
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山
• [Presentation] 癌に関するシグナルを標的とした天然物の探索 (2009)
  • Author(s): 石橋正己
  • Organizer: 第3回日本化学会関東支部大会
  • Place of Presentation: 東京
  • Year and Date: 2009-09-04
• [Presentation] Excoecaria indicaからのWntシグナルを活性化する天然物の探索 (2009)
  • Author(s): 山口達弘, 大槻崇, 李暁帆, A. K. Paul, M. I. Ahmed, S. K. Sadhu, 石橋正己
  • Organizer: 日本薬学会第129年会
  • Place of Presentation: 京都
• [Presentation] Bioactive components from medicinal plants of Bangladesh for abrogating TRAIL-resistance (2009)
  • Author(s): F. Ahmed, T. Ohtsuki, M. Rahman, S. K. Sadhu, K. Toume, M. Ishibashi
  • Organizer: 日本生薬学会第56年会
  • Place of Presentation: 京都
• [Presentation] Bioactive constituents from Vallaris solanaceae and Curcuma parviflora (2009)
  • Author(s): S. K. Sadhu, F. Ahmed, K. Toume, M. Tamaki, T. Ohtsuki, T. Koyano, T. Kowithayakorn, M. Ishibashi
  • Organizer: 日本生薬学会第56年会
  • Place of Presentation: 京都
• [Presentation] Bioactive Constituents from Tropical Medicinal Plants of Bangladesh (2008)
  • Author(s): S. K. Sadhu
  • Organizer: 日本生薬学会第55年会
  • Place of Presentation: 長崎
  • Year and Date: 2008-09-20
• [Presentation] Bioactive Constituents from Tropical Medicinal Plants of Bangladesh (2008)
  • Author(s): S. K. Sadhu, F. Ahmed, T. Ohtsuki, M. Ishibashi
  • Organizer: 日本生薬学会
  • Place of Presentation: 長崎
• [Book] 自然のなかに薬をさがす～千葉発の天然物研究小話 (2011)
  • Author(s): 石橋正己
  • Total Pages: 94
  • Publisher: 千葉日報社
• [Book] ベーシック有機構造解析 (2011)
  • Author(s): 森田博史, 石橋正己
  • Total Pages: 214
  • Publisher: 化学同人
• [Book] ソレル有機化学 (2009)
  • Author(s): 村田道雄, 石橋正己, 木越英夫, 佐々木誠(監訳)
  • Total Pages: 854
  • Publisher: 東京化学同人
• [Book] ソレル有機化学 (2009)
  • Author(s): 村田道雄
  • Total Pages: 854
  • Publisher: 東京化学同人
• [Book] 天然物化学ー海洋生物編,山村庄介・長谷川宏司・木越英夫編 (2008)
  • Author(s): 石橋正己
  • Total Pages: 9
  • Publisher: アイピーシー, 2008, 182-190.
• [Remarks]
  • URL: http://www.p.chiba-u.ac.jp/lab/kouzou/
• [Remarks] ホームページ
  • URL: http://www.p.chiba-u.ac.jp/lab/kouzou/
• [Remarks]
  • URL: http://www.p.chiba-u.ac.jp/lab/kouzou/
• [Remarks]
  • URL: http://www.p.chiba-u.ac.jp/lab/kouzou/
• [Remarks]
  • URL: http://www.p.chiba-u.ac.jp/lab/kouzou/
• [Patent(Industrial Property Rights)] キシログラニンA (2011)
  • Inventor(s): 石橋正己, 神谷謙太朗, 森直美, 當銘一文
  • Industrial Property Rights Holder: 千葉大学
  • Industrial Property Number: 2011-048388
  • Filing Date: 2011-03-04
• [Patent(Industrial Property Rights)] イズミフェナジンA (2010)
  • Inventor(s): M. Abdelfattah, 當銘一文, 石橋正己
  • Industrial Property Rights Holder: 千葉大学
  • Industrial Property Number: 2010-045993
  • Filing Date: 2010-03-02
• [Patent(Industrial Property Rights)] コンブレチン酸A及びB (2010)
  • Inventor(s): 石橋正己, 中澤孝文, 當銘一文, 小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Industrial Property Number: 2010-041883
  • Filing Date: 2010-02-26
• [Patent(Industrial Property Rights)] ツビフェラールAおよびツビフェラールB (2010)
  • Inventor(s): 石橋正己, 鎌田和明
  • Industrial Property Rights Holder: 千葉大学
  • Acquisition Date: 2010-03-05
• [Patent(Industrial Property Rights)] コンブレチン酸A及びB (2010)
  • Inventor(s): 石橋正己・中澤孝文・當銘一文・小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Industrial Property Number: 2010-041883
  • Filing Date: 2010-02-26
• [Patent(Industrial Property Rights)] コンブレチン酸A及びB (2010)
  • Inventor(s): 石橋正己
  • Industrial Property Rights Holder: 千葉大学
  • Filing Date: 2010-02-26
• [Patent(Industrial Property Rights)] パルビフロレンHおよびパルビフロレンI (2009)
  • Inventor(s): 石橋正己, 當銘一文, 小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Acquisition Date: 2009-08-21
• [Patent(Industrial Property Rights)] エリスロフレシンA,B,C,及びD (2009)
  • Inventor(s): 石橋正己・宮川高・大槻崇・小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Industrial Property Number: 2009-108489
  • Filing Date: 2009-04-27
• [Patent(Industrial Property Rights)] パルビフロレンHおよびパルビロレンI (2009)
  • Inventor(s): 石橋正己・當銘一文・小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Acquisition Date: 2009-08-21
• [Patent(Industrial Property Rights)] ブランジシアニンA,B及びC並びにこれを用いた薬剤 (2008)
  • Inventor(s): 石橋正己・菊地博之・大槻崇・小谷野喬
  • Industrial Property Rights Holder: 千葉大学
  • Patent Publication Number: 2008-150309
  • Acquisition Date: 2008-07-03