• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Geriatric and gerontological approach for asian elderly to prevent their atherosclerotic disease and get successful aging.

Research Project

Project/Area Number 20406004
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Gender
Research InstitutionNagoya University

Principal Investigator

HAYASHI Toshio  名古屋大学, 医学部・附属病院, 講師 (80303634)

Co-Investigator(Kenkyū-buntansha) UMEGAKI Hiroyuki  名古屋大学, 医学部附属病院, 助教 (40345898)
SUZUKI Yoshikatsu  名古屋市立大学, 医学部附属病院, 准教授 (30254288)
Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Keywords閉経後女性 / 動脈硬化性疾患 / 老化 / ホルモン補充療法 / 一酸化窒素 / 動脈硬化症 / エストロゲン / メタボリック症候群 / 遺伝子変異 / 血管内皮細胞
Research Abstract

As the summary, I introduce two studies in three east asian countries(Japan, China and Korea). We reported the presence of genetic mutations in relation to thrombosis or atherosclerosis in elderly women with a mean age of 80. 9. Three relations like Factor VII Arg353Gln and HDL-C were linked.
The second study was the prevalence of depression and the association with QoL in community-dwelling postmenopausal women in three Asian countries. 698 postmenopausal women participated. Subjects with depression were 39. 0% of the Korean, 29. 2% of the Chinese, and 33. 9% of the Japanese. Depression was, associated with lower levels of QoL. 80% of women wish to be informed that they have cancer.

Report

(6 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (159 results)

All 2012 2011 2010 2009 2008 Other

All Journal Article (71 results) (of which Peer Reviewed: 70 results) Presentation (80 results) Book (7 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Management of type IIb dyslipidemia J Atheroscl Thoromb2012

    • Author(s)
      Arai H, Ishibashi S, Bujo H, Hayashi T, Yamada N., et al
    • Volume
      (in press)
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Back-ground to discuss guidelines for control of plasma HDL-cholesterol in Japan : A revised edition of the report on the meeting of the Research Group for the Management of Primary Hyperlipidemia J Atheroscl Thoromb2012

    • Author(s)
      Yokoyama S, Yamashita S, Hayashi T, Gotoda T, Yamada N., et al
    • Volume
      (in press)
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients2012

    • Author(s)
      Hayashi T, Kawashima S, Nomura H, et al
    • Journal Title

      Cardiovasc Diabetol

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Management of type I and V hyperlipidemia The Research Committee for Primary Hyperlipidemia, Research on Measures against Intractable Diseases by the Ministry of Health, Labor, and Welfare in Japan2012

    • Author(s)
      Gotoda T, Arai H, Hayashi T, Yamada N, et al
    • Journal Title

      J A T

      Volume: 19 Pages: 1-12

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Short-term effects of L-citrulline on arterial stiffness in middle-aged men2012

    • Author(s)
      Ochiai M, Hayashi T, et al
    • Journal Title

      Int. J. Cardiology

      Volume: 155 Pages: 257-261

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men2012

    • Author(s)
      Ochiai M, Hayashi T, Morita M, Ina K, Maeda M, Watanabe F, Morishita K
    • Journal Title

      Int.J.Cardiology

      Volume: 155 Issue: 2 Pages: 257-261

    • DOI

      10.1016/j.ijcard.2010.10.004

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Background to Discuss Guidelines for Control of Plasma HDL-Cholesterol in Japan*2012

    • Author(s)
      Yokoyama S, Yamashita S, Ishibashi S, Sone H, Oikawa S, Shirai K, Ohta T, Bujo H, Kobayashi J, Arai H, Harada-Shiba M, Eto M, Hayashi T, Gotoda T, Suzuki H, Yamada N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 3 Pages: 207-212

    • DOI

      10.5551/jat.11452

    • NAID

      130004444591

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Management of Type IIb Dyslipidemia2012

    • Author(s)
      Arai H, Ishibashi S, Bujo H, Hayashi T, Yokoyama S, Oikawa S, Kobayashi J, Shirai K, Ota T, Yamashita S, Gotoda T, Harada-Shiba M, Sone H, Eto M, Suzuki H, Yamada N.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 2 Pages: 105-114

    • DOI

      10.5551/jat.10447

    • NAID

      130004444573

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diagnosis and Management of Type I and Type V Hyperlipoproteinemia2012

    • Author(s)
      Gotoda T, Shirai K, Ohta T, Kobayashi J, Yokoyama S, Oikawa S, Bujo H, Ishibashi S, Arai H, Ya mashita S, Harada-Shiba M, Eto M, Hayashi T, Sone H, Suzuki H, Yamada N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 1 Pages: 1-12

    • DOI

      10.5551/jat.10702

    • NAID

      130004721898

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depression, quality of life(QoL) and will to live of community-dwelling postmenopausal women in three Asian countries : Korea, China and Japan2011

    • Author(s)
      Ina K, Hayashi T, Nomura H, Ishitsuka A, Hirai H, Iguchi A
    • Journal Title

      Archive Ger. Gel

      Volume: 53 Pages: 8-12

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of selective estrogen receptor modulator treatment following hormone replacement therapy on elderly postmenopausal women with osteoporosis2011

    • Author(s)
      Hayashi T, Ina K, Maeda M, Nomura H
    • Volume
      34
    • Pages
      199-203
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dose-Dependent Modulatory Effects of Insulin on Glucose-induced Endothelial Senescence in vitro and in vivo : A Relationship between Telomeres and Nitric Oxide2011

    • Author(s)
      Matsui-Hirai H, Hayashi T, Ignarro LJ, Hattori Y, et al
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 337 Pages: 591-599

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Place of death for the elderly in need of end-of-life home care : A study in Japan2011

    • Author(s)
      Hayashi T, Nomura H, et. al
    • Journal Title

      Arch Gerontol Geriatr

      Volume: 53 Pages: 242-244

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enodothelial Progenitor Cells as Therapeutic Agents in the Microcirculation2011

    • Author(s)
      Napoli C, Cacciatore F, Hayashi T, Ignarro LJ., et al
    • Journal Title

      Atherosclerosis

      Volume: 215 Pages: 9-22

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The role of insulin growth factor on atherosclero-sis and endothelial function : The effect on hyper-lipidemia and aging2011

    • Author(s)
      Hirai H, Maeda M, Qungfang D, Hayashi T
    • Journal Title

      Life Sci

      Volume: 88 Pages: 425-31

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Depression, quality of life (QoL) and will to live of community-dwelling postmenopausal women in three Asian countries : Korea, China and Japan2011

    • Author(s)
      Ina K, Hayashi T, Nomura H, Ishitsuka A, Hirai H, Iguchi A
    • Journal Title

      Arch Gerontol Geriatr.

      Volume: 53 Issue: 1 Pages: 8-12

    • DOI

      10.1016/j.archger.2010.05.010

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of insulin growth factor on atherosclerosis and endotbelial function : the effect on hyperlipidemia and aging2011

    • Author(s)
      Hirai H, Kanaya R, Maeda M, Qungfang D, Ina K, Hayashi T
    • Journal Title

      Life Sci

      Volume: 88 Issue: 9-10 Pages: 425-431

    • DOI

      10.1016/j.lfs.2010.12.021

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients2011

    • Author(s)
      Hayashi T, Kawashima S, Nomura H, Itoh H, Wa tanabe H, Ohrui T, Yokote K, Sone H, Hattori Y, Yoshizumi M, Ina K, Kubota K. Age, gender
    • Journal Title

      Cardiovasc Diabetol

      Volume: 10 Issue: 1 Pages: 86-86

    • DOI

      10.1186/1475-2840-10-86

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of selective estrogen receptor modulator treatment following hormone replacement therapy on elderly postmenopausal women with osteoporosis2011

    • Author(s)
      Hayashi T, Ina K, Maeda M, Nomura H
    • Journal Title

      Nitric Oxide

      Volume: 24 Issue: 4 Pages: 199-203

    • DOI

      10.1016/j.niox.2011.04.002

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dose-Dependent Modulatory Effects of Insulin on Glucoseinduced Endothelial Senescence in vitro and in vivo : A Relationship between Telomeres and Nitric Oxide2011

    • Author(s)
      Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro L.J., Hattori Y
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 337 Issue: 3 Pages: 591-599

    • DOI

      10.1124/jpet.110.177584

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of lower hemoglobin level with depressive mood in elderly women at high risk of requiring care2011

    • Author(s)
      Umegaki H, Yanagawa M, Endo H.
    • Journal Title

      Geriatr Gerontol Int. 印刷中

    • NAID

      10031147962

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Place of death for the elderly in need of end-of-life home care: A study in Japan.2011

    • Author(s)
      Hayashi T, Nomura H, 他5名1番目
    • Journal Title

      Arch Gerontol Geriatr 印刷中

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Depression, quality of life (QoL) and will to live of community-dwelling postmenopausal women in three Asian countries: Korea, China and Japan.2011

    • Author(s)
      Ina K, Hayashi T, Nomuraa H,Ishitsukaa A, Hirai H, Iguchi A
    • Journal Title

      Archive Ger.ontol Geriatr 印刷中

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Dose-Dependent Modulatory Effects of Insulin on Glucose-induced Endothelial Senescence in vitro and in vivo : A Relationship between Telomeres and Nitric Oxide2011

    • Author(s)
      Matsui-Hirai H, Hayashi T,Yamamoto S, 他6名
    • Journal Title

      J Pharmacol Exp Ther

      Volume: (印刷中,印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Place of death for the elderly in need of end-of-life home care : A study in Japan.2011

    • Author(s)
      Hayashi T, Nomura H, 他5名
    • Journal Title

      Arch Gerontol Geriatr

      Volume: (印刷中,印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men2011

    • Author(s)
      Ochiai M, Hayashi T, Morita M., 他4名
    • Journal Title

      Int.J.Cardiology

      Volume: (印刷中,印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depression, quality of life (QoL) and will to live of community-dwelling postmenopausal women in three Asian countries : Korea, China and Japan.2011

    • Author(s)
      Ina K, Hayashi T, Nomuraa H, Ishitsukaa A, Hirai H, Iguchi A
    • Journal Title

      Archive Ger.ontol Geriatr

      Volume: (印刷中,印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enodothelial Progenitor Cells as Therapeutic Agents in the Microcirculalion.2011

    • Author(s)
      Napoli C, Cacciatore F, Hayashi T, 他4名
    • Journal Title

      Atherosclerosis

      Volume: 215 Pages: 9-22

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of insulin growth factor on atherosclerosis and endothelial function : The effect on hyperlipidemia and aging.2011

    • Author(s)
      Hirai H, Kanaya R, Maeda M, Qungfang D, Ina K, Hayashi T
    • Journal Title

      Life Sci

      Volume: 88 Pages: 425-431

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of lower hemoglobin level with depressive mood in elderly women at high risk of requiring care2011

    • Author(s)
      Umegaki H, Yanagawa M, Endo H.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: (印刷中,印刷中)

    • NAID

      10031147962

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possibility of the regression of atherosclerosis through prevention of endothelial senescence by regulation of nitric oxide and free radical scavengers2010

    • Author(s)
      Hayashi T, Iguchi A
    • Journal Title

      Geriatr Gerontol Int

      Volume: 10 Pages: 115-130

    • NAID

      10027271886

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A hydroxymethylglutaryl coenzyme a reductase inhibitor improves endothelial function within 7 days in patients with chronic hemodialysis2010

    • Author(s)
      Kishimoto N, Hayashi T, Sakuma I, et al
    • Journal Title

      Int J Cardiol

      Volume: 145 Pages: 21-26

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy Proc Natl Acad Sci U S A2010

    • Author(s)
      Nigrisa F, Hayashii T, Ignarro LJ, Napoli C, et al
    • Volume
      107
    • Pages
      14484-89
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phospho-rylation and dephosphorylation in endothelial cells2010

    • Author(s)
      Zhang X-H, Hayashi T, et. al
    • Journal Title

      Br J Pharmacology

      Volume: 159 Pages: 928-938

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A glucagon-like peptide-1 analogue, liraglutide, upregulates NO production and exerts anti-inflammatory action in endothelial cells Diabetologia2010

    • Author(s)
      Hattori Y, Hayashi T., et al
    • Volume
      53
    • Pages
      2256-63
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dose-Dependent Modulatory Effects of Insulin on Glucose-induced Endothelial Senescence in vitro and in vivo: A Relationship between Telomeres and Nitric Oxide2010

    • Author(s)
      Matsui-Hirai H, Hayashi T, Yamamoto S, 他6名2番目
    • Journal Title

      J Pharmacol Exp Ther 印刷中

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers.2010

    • Author(s)
      Hayashi T, Iguchi A
    • Journal Title

      Geriatr Gerontol Int. 10

      Pages: 115-130

    • NAID

      10027271886

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy2010

    • Author(s)
      de Nigrisa F, Crudelea V, Hayashii T, Ignarroj LJ, Napoli C, 他9名3番目
    • Journal Title

      Proc Natl Acad Sci U S A 107

      Pages: 14484-14489

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] A hydroxymethylglutaryl coenzyme a reductase inhibitor improves endothelial function within 7days in patients with chronic hemodialysis2010

    • Author(s)
      Kishimoto N, Hayashi T, Sakuma I, Kano-Hayashi H, 他5名
    • Journal Title

      Int J Cardiol.

      Volume: 145 Pages: 21-26

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effect of the oligomerized polyphenol oligonol on high glucose- induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells.2010

    • Author(s)
      Zhang XH, Yokoo H, Nishioka H, Fujli H, Matsuda N, Hayashi T, Hattori Y.
    • Journal Title

      Br J Pharmacol

      Volume: 159 Pages: 928-938

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers2010

    • Author(s)
      Hayashi T, Iguchi A
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 10 Pages: 115-130

    • NAID

      10027271886

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy2010

    • Author(s)
      de Nigrisa F, Crudelea V, Hayashii T,, Ignarroj LJ, Napoli C, 他9名
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 14484-14489

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of educational background on verbal fluency task performance in older adults with Alzheimer's disease and mild cognitive impairment.2010

    • Author(s)
      Kawano N, Umegaki H, Suzuki Y, Yamamoto S, Mogi N, Iguchi A.
    • Journal Title

      Int Psychogeriatr

      Volume: 22 Pages: 995-1002

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers2010

    • Author(s)
      Hayashi T, Iguchi A
    • Journal Title

      Geriatr Gerontol Int. (印刷中)

    • NAID

      10027271886

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A hydroxymethylglutaryl coenzyme a reductase inhibitor improves endothelial function within 7 days in patients with chronic hemodialysis2010

    • Author(s)
      Kishimoto N, Hayashi T, Sakuma I, Kano-Hayashi H, Tsunekawa T, Osawa M, Ina K, Iguchi A.
    • Journal Title

      Int J Cardiol. (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Beneficial effect of the oligomerized polyphenol oligonol on high glucose- induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells2010

    • Author(s)
      Zhang XH, Yokoo H, Nishioka H, Fujii H, Matsuda N, Hayashi T, Hattori Y.
    • Journal Title

      Br J Pharmacol (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly with Type 2 Diabetes Mellitus2010

    • Author(s)
      Sakurai T, Iimuro S, Araki A, Umegaki H, Ohashi Y, Yokono K Ito H
    • Journal Title

      Gerontology (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pathophysiology of cognitive dysfunction in older people with type 2 dia betel : vascular changes or neurodegeneration?2010

    • Author(s)
      Umegaki H
    • Journal Title

      Age Ageing. 39

      Pages: 8-10

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women2009

    • Author(s)
      Funami J, Hayashi T, Nomura H, Ding QF, Ishitsuka-Watanabe A, Matsui-Hirai H, Ina K, Zhang J, Yu ZY, Iguchi A
    • Journal Title

      Life Sci

      Volume: 85 Pages: 316-21

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] HDL relates the risk of stroke in very elderly diabetic individuals : The change in the risk factors for atherosclerotic diseases at various ages2009

    • Author(s)
      Hayashi T, Itoh H, Watanabe H, Iguchi A, et al
    • Journal Title

      Diabetes Care

      Volume: 32 Pages: 1221-3

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals : changes in the risk for atherosclerotic diseases at various ages2009

    • Author(s)
      Hayashi T, Kawashima S, Itoh H, 他9名(1番目), on behalf of Japan CDM group
    • Journal Title

      Diabetes Care 32

      Pages: 1221-1223

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women2009

    • Author(s)
      Funami J, Hayashi T, Nomura H, Ding QF, Ishitsuka Watanabe A, Matsui-Hirai H, Ina K, Zhang J, Yu ZY, Iguchi A.
    • Journal Title

      Life Sciences 85

      Pages: 316-321

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet a crossover meal tolerance study2009

    • Author(s)
      Haimoto H, Sasakabe T, Umegaki H Wakai K
    • Journal Title

      Nutr Metab (Lond) 6

      Pages: 52-52

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of higher carbohydrate intake with depressive mood in elderly diabetic women2009

    • Author(s)
      Umegaki H, Iimuro S, Araki A, Sakurai T, Iguchi A, Yoshimura Y, Ohashi Y, Ito H.
    • Journal Title

      Nutr Neurosci. 12

      Pages: 267-271

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      Hayashi T, Iguchi A.
    • Journal Title

      Free radicals as atherosclerotic risk-The relation of NO (Chapter 21)(Elsevier Co.Ltd.)

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Low HDL-cholesterol is associated with Hie risk of stroke in elderly diabetic individuals : Changes in the risk at various ages.2009

    • Author(s)
      Hayashi T, Kawashima S, Itoh H, (他9名1番目), on behalf of Japan CDM group.
    • Journal Title

      Diabetes Care (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitric oxide and endothelial cellular senescence2008

    • Author(s)
      Hayashi T, Yano K, et al
    • Journal Title

      Pharmacol Ther

      Volume: 120 Pages: 333-9

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Importance of lipid levels in elderly diabetic individuals : baseline characteristics and 1-year survey of cardiovascular events2008

    • Author(s)
      Hayashi T, Kawashima S, et al
    • Journal Title

      Circ J

      Volume: 72 Pages: 218-25

    • NAID

      110006571047

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Augmentation of vascular remodeling by uncoupled endothelial NO synthase in a mouse model of diabetes mellitus2008

    • Author(s)
      Sasaki N, Hayashi T, Kawashima S., et al
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 28 Pages: 1068-76

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pitavastatin Shows Promise in Treatment of Patients With Type 2 Diabetes2008

    • Author(s)
      Hayashi T, Iguchi A
    • Journal Title

      Review of Endocrinology

      Volume: 1 Pages: 1-3

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proposed Guideleins for Hypertriglyceridemia in Japan with non-HDL Cholesterol as the second Target2008

    • Author(s)
      Simano H, Arai H, Hayashi T, Yamada N., et al
    • Journal Title

      J Atherosclero Thromb

      Volume: 15 Pages: 116-121

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the entorhinal cortex on diurnal ACTH and corticosterone release in rats2008

    • Author(s)
      Zhu W, Zhang R, Hu C, Umegaki H.
    • Journal Title

      Neuro Endocrinol Lett. 29

      Pages: 159-162

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of Lipid Levels in Elderly Diabetic Individuals-Baseline Characteristics and 1-year Survey of Cardiovascular Events -2008

    • Author(s)
      Hayashi T, Kawashima S, Itoh H, (他9名1番目), on behalf of Japan CDM group
    • Journal Title

      Circuon Journal 72

      Pages: 208-225

    • NAID

      110006571047

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitric oxide and eudoftielial cellular senesceace2008

    • Author(s)
      Hayashi T, Yano K, (他4名1番目)
    • Journal Title

      Pharmacol Ther 120

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Augmentalion of Vascular Remodeling by Uncoupled Endothelial Nitric Oxide Synthase in a Mouse Model of Diabetes Mellitus.2008

    • Author(s)
      Sasaki N, Yamashita T, Takaya T, Shinohara M, Fukatsu A, Havashi T, (他4名6番目)
    • Journal Title

      Arteriosclerosis Thrombosis and Vascular Biology 28

      Pages: 1068-1076

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pitavastatin Shows Promise in Treatment of Patients With Type 2 Diabetes2008

    • Author(s)
      Hayashi T, Yokote K, Saito Y, Iguchi A.
    • Journal Title

      Review of Endocrinology 1

      Pages: 1-3

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visceral fat contribution of insulin resistance in elderly people.2008

    • Author(s)
      Umegaki H. Haimoto H, Kario K.
    • Journal Title

      J Am Geriafr Soc 56

      Pages: 1373-1375

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.2008

    • Author(s)
      Thanos PK Mchaelides M, Umegaki H. Volkow ND.
    • Journal Title

      Synapse 62

      Pages: 481-486

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Glucose control levels, ischaemic brain lesions, and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly.2008

    • Author(s)
      Umegaki H, Kawamura T, Mogi N, Umemura T, Kanai A, Sano T.
    • Journal Title

      Age Ageing 37

      Pages: 458-461

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the entcrhinal cortex on diumal ACTH and corticosterone release in rats.2008

    • Author(s)
      Zhu W, Zhang R, Hu C, Umegaki H.
    • Journal Title

      Neuro Endocrinol Lett. 29

      Pages: 159-162

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patieats.2008

    • Author(s)
      Umegaki H, Iimuro S, (他6名, 1番目).
    • Journal Title

      Neurobiol Agjng. 29

      Pages: 1022-10026

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 動脈硬化症とアミノ酸ーアルギニン,シトルリンを中心にー2011

    • Author(s)
      林登志雄
    • Organizer
      日本アミノ酸学会第4回夏のシンポジウム
    • Place of Presentation
      新潟
    • Year and Date
      2011-09-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 動脈硬化症とアミノ酸-アルギニン,シトルリンを中心に-2011

    • Author(s)
      林登志雄
    • Organizer
      平成23年度日本アミノ酸学会第4回夏のシンポジウム
    • Place of Presentation
      新潟(招待講演)
    • Year and Date
      2011-09-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生活習慣病,老化とアミノ酸2011

    • Author(s)
      林登志雄
    • Organizer
      第5回日本アミノ酸学会年次集会
    • Place of Presentation
      名古屋ワークショップ
    • Related Report
      2011 Final Research Report
  • [Presentation] Low HDL-Cholesterol is Associated With Risk of Ischemic heart disease and Stroke in Elderly Diabetic Patients2011

    • Author(s)
      Hayashi T, Ina K, et al
    • Organizer
      9^<th> Asia/Oceania Regional Congress of Gerontology and Geriatrics Gerontology and Geriatrics
    • Place of Presentation
      Melbourune Australia
    • Related Report
      2011 Final Research Report
  • [Presentation] Dose-Dependent Modulatory Effects of Insulin on Glucose-induced Endothelial Senescence in vitro and in vivo : A Relationship between Telomeres and NO2011

    • Author(s)
      Hayashi T, et al.
    • Organizer
      9^<th> Asia/Oceania Regional Congress of Gerontology and Geriatrics Gerontology and Geriatrics
    • Place of Presentation
      Melbourune Australia
    • Related Report
      2011 Final Research Report
  • [Presentation] Place of death for the elderly in need of end-of-life home care2011

    • Author(s)
      Ina K, Hayashi T, et al
    • Organizer
      9^<th> Asia/Oceania Regional Congress of Gerontology and Geriatrics Gerontology and Geriatrics
    • Place of Presentation
      Melbourune Australia
    • Related Report
      2011 Final Research Report
  • [Presentation] 糖尿病合併心血管病への動脈硬化危険因子の影響-5年度調査-2011

    • Author(s)
      林登志雄, 他9名
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 高血圧モデル・アンギオテンシンIIによる血管内皮細胞老化はHMG-CoA還元酵素阻害剤により回復する2011

    • Author(s)
      林登志雄伊奈孝一郎
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 細胞老化抑制物質の検討.高グルコースモデルを用いて-2011

    • Author(s)
      林登志雄,伊奈孝一郎
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 在宅医療において在宅しを規定する因子について検討2011

    • Author(s)
      伊奈孝一郎,林登志雄, 他4名
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 糖尿病患者薬物療法医療経済解析のためのアセスメントモデル2011

    • Author(s)
      伊奈孝一郎,林登志雄
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 脂質異常症合併糖尿病患者の薬物療法における医療経済解析用アセスメントモデル2011

    • Author(s)
      伊奈孝一郎,林登志雄
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Related Report
      2011 Final Research Report
  • [Presentation] Clinical Approach for Atherosclerosis in Elderly2011

    • Author(s)
      Hayashi T
    • Organizer
      The 20^<th> Korea Lipid and Atherosclerosis Society Annual Meeting
    • Place of Presentation
      Seoul Korea Special Invited Lecture
    • Related Report
      2011 Final Research Report
  • [Presentation] 在宅医療において在宅死を規定する因子についての検討2011

    • Author(s)
      伊奈孝一郎, 林登志雄, 野村秀樹, 広瀬貴久, 野々垣禅, 鈴木祐介
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 糖尿病合併脂質異常症患者薬物療法における医療経済解析のためのアセスメントモデル2011

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細胞老化抑制物質の検討-高グルコースモデルを用いて-2011

    • Author(s)
      林登志雄, 伊奈孝一郎
    • Organizer
      第53回日本老年医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脂質異常症合併糖尿病患者の薬物療法における医療経済解析用アセスメントモデル2011

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      第54回日本糖尿病学会学術集会
    • Place of Presentation
      札幌
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生活習慣病、老化とアミノ酸2011

    • Author(s)
      林登志雄
    • Organizer
      日本アミノ酸学会第5回学術大会(JSAAS 2011)
    • Place of Presentation
      名古屋(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Low HDL-Cholesterol is Associated With Risk of Ischemic heart disease and Stroke in Elderly Diabetic Individuals2011

    • Author(s)
      Havashi T, Ina K, Nomura H, on behalf of JCDM investigators
    • Organizer
      9th Asia/Oceania Regional Congress of Gerontology and Geriatrics Gerontology and Geriatrics
    • Place of Presentation
      Melbourune Australia
    • Related Report
      2011 Annual Research Report
  • [Presentation] Dose-Dependent Modulatory Effects of Insulin on Glucose-induced Endothelial Senescence in vitro and in vivo : A Relationship between Telomeres and Nitric Oxide2011

    • Author(s)
      Hayashi T, Hirai H, Ina K, Nomura H
    • Organizer
      9th Asia/Oceania Regional Congress of Gerontology and Geriatrics Gerontology and Geriatrics
    • Place of Presentation
      Melbourune Australia
    • Related Report
      2011 Annual Research Report
  • [Presentation] における原発性高脂血症の実態と診療の在り方ー早期診断と在宅医療2010

    • Author(s)
      林登志雄
    • Organizer
      愛知県難病研究会特別講演
    • Place of Presentation
      愛知県
    • Year and Date
      2010-11-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Clinical Approach for Atherosclerosis in Elderly.2010

    • Author(s)
      Hayashi T.
    • Organizer
      The 20th Korea Lipid and Atherosclerosis Society Annual Meeting
    • Place of Presentation
      Korea(特別招待講演)Special Invited Lecture
    • Year and Date
      2010-09-07
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Clinical Approach for Atherosclerosis in Elderly2010

    • Author(s)
      Hayashi T.
    • Organizer
      The 20^<th> Korea Lipid and Atherosclerosis Society Annual MeetingSpecial Invited Lecture
    • Place of Presentation
      Seoul, Korea(特別招待講演)
    • Year and Date
      2010-09-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 糖尿病合併脂質異常症の心血管病危険因子としての寄与-複合型高脂血症を中心とした年齢別検討2010

    • Author(s)
      伊奈孝一郎, 林登志雄, 他2名2番目
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 糖尿病合併脂質異常症の心血管病危険因子としての寄与一複合型高脂血症を中心とした年齢別検討2010

    • Author(s)
      伊奈孝一郎, 林登志雄, 他2名
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高齢者ワーファリン治療の留意点2010

    • Author(s)
      広瀬貴久、林登志雄
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report 2010 Self-evaluation Report
  • [Presentation] 食後高血糖モデル:グルコース間歇刺激は新しい機序で血管内皮細胞を老化させる2010

    • Author(s)
      林登志雄, 他3名
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 糖尿病合併心血管病危険因子の検討-高齢者インスリン治療-2010

    • Author(s)
      林登志雄, 他3名
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 老化と内皮機能障害/動脈硬化2010

    • Author(s)
      林登志雄
    • Organizer
      第52回日本老年医学会学術集会 シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report 2010 Self-evaluation Report
  • [Presentation] 血管老化を標的としたNOを介する抗動脈硬化療法-グルコース及びインスリンの作用を中心に2010

    • Author(s)
      林登志雄
    • Organizer
      第34回日本基礎老化学会学術集会シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Angiotensin II stimuli, model of hypetension, induced endothelial senenscence is totally restored by HMG-CoA reductase inhibitor2010

    • Author(s)
      榊原泰史、前田守彦、伊奈孝一郎、平井寿子、林登志雄
    • Organizer
      第34回日本基礎老化学会学術集会ワークショップ
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Intermittent high glucose stimuli promote endonthelial senescence : Model of impaired glucose tolerance2010

    • Author(s)
      前田守彦、林登志雄, 他3名
    • Organizer
      第34回日本基礎老化学会学術集会ワークショップ
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Differences in the risk of stroke and ischemic heart disease by age among diabetic patients receiving insulin therapy2010

    • Author(s)
      Hayashi T., 他3名1番目
    • Organizer
      Annual Scientific Meeting American Geriatrics Society
    • Place of Presentation
      Orlando, Fl, USA
    • Year and Date
      2010-05-08
    • Related Report
      2010 Annual Research Report 2010 Self-evaluation Report
  • [Presentation] Depression, quality of life and will to live of community- dwelling postmenopausal women in three Asian countries: Korea, China and Japan.2010

    • Author(s)
      Ina K, Hayashi T, Nomura H, Ishitsuka A, Hirai H, Iguchi A
    • Organizer
      Annual Scientific Meeting American Geriatrics Society
    • Place of Presentation
      orlando, Fl, USA
    • Year and Date
      2010-05-08
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Depression, quality of life and will to live of community- dwelling postmenopausal women in three Asian countries : Korea, China and Japan2010

    • Author(s)
      Ina K, Hayashi T, Nomura H, Ishitsuka A, Hirai H, Iguchi A
    • Organizer
      Annual Scientific Meeting American Geriatrics Society
    • Place of Presentation
      Orlando, Fl, USA
    • Year and Date
      2010-05-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 老化と内皮機能障害/動脈硬化2010

    • Author(s)
      林登志雄
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸シンポジウム
    • Related Report
      2011 Final Research Report
  • [Presentation] Differences in the risk of stroke and ischemic heart disease by age among diabetics with insulin2010

    • Author(s)
      Hayashi T, et al
    • Organizer
      2010American Geriatric Society MEETING
    • Place of Presentation
      Orlando Fl, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Depression, quality of life and will to live of community-dwelling postmenopausal women in : Korea, China and Japan2010

    • Author(s)
      Ina K, Hayashi T, et al
    • Organizer
      2010American Geriatric Society MEETING
    • Place of Presentation
      Orlando Fl, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Interactions of glucose and insulin in regulation of replicative and stress-induced endothelial senescence―The relationship between telomere and nitric oxide―2009

    • Author(s)
      Hayashi T., Mastsui-Hirai H
    • Organizer
      America's Gerontology Society 62nd Annual Scientific Meeting
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2009-11-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Depression, Quality of Life and Living will of community-dwelling postmenopausal and elderly women in three asian countries, Japan, Korea and China2009

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      19^<th> IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      Pans, France
    • Year and Date
      2009-07-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low HDL-cholesterol is associated with the risk of stroke in elderly diabetic individuals2009

    • Author(s)
      林登志雄, 他10名(1番目)
    • Organizer
      19^<th> IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      Paris, France
    • Year and Date
      2009-07-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low HDL- cholesterol is associated with the risk of stroke in elderly diabetic in dividuals : Changes in the risk for atherosclerotic diseases at various ages2009

    • Author(s)
      林登志雄, 他10名(1番目)
    • Organizer
      American Diabetes Association's 69th Scientific Sessions
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-06-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] A new view of atherosclerosis related pharmacogenetics based gene analysis in Japanese elderly women2009

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      The 10^<th> International Symposium on Mechanisms of Vasodiatation
    • Place of Presentation
      Matsushima, Miyagi, JAPAN
    • Year and Date
      2009-06-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Biphsic effects of insulin on endothelial senescence2009

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      The 10^<th> International Symposium on Mechanisms of Vasodiatation
    • Place of Presentation
      Matsushima, Miyagi, JAPAN
    • Year and Date
      2009-06-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 糖尿病罹患者における脳卒中リスクとしての脂質の影響-年齢による危険因子の変化-2009

    • Author(s)
      伊奈孝一郎, 林登志雄
    • Organizer
      第52回日本糖尿病学会学術集会優秀演題
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 血管内皮細胞老化におけるグルコースとインシュリンの役割2009

    • Author(s)
      林登志雄, 他3名(1番目)
    • Organizer
      第52回日本糖尿病学会学術集会優秀演題
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 「シトルリン・疾患治療への応用と展望」シトルリン~NO産生と動脈硬化予防への展望2009

    • Author(s)
      林登志雄
    • Organizer
      第9回日本NO学術集会 セミナー
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] グルコースとインスリンの細胞老化ストレスを介する動脈硬化への作用2009

    • Author(s)
      林登志雄
    • Organizer
      第9回日本NO学術集会 シンポジウムNOとインスリン抵抗性-糖尿病・老化)
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] The role of glucose and insulin on endothelial senescence- The relation of diversity effect of insulin and telomerase-2009

    • Author(s)
      林登志雄, 他3名(1番目)
    • Organizer
      Annual Scientific Meeting American Geriatrics Society
    • Place of Presentation
      Chicago USA
    • Year and Date
      2009-05-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Interactions of glucose and insulin in regulation of replicative and stress-induced senescence2009

    • Author(s)
      Hayashi T, et al
    • Organizer
      America's Gerontology Society 62nd Annual Scientific Meeting
    • Place of Presentation
      Atlanta, GA
    • Related Report
      2011 Final Research Report
  • [Presentation] Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men2009

    • Author(s)
      M. Ochiai、T. Hayashi
    • Organizer
      第41回日本動脈硬化学会学術集会
    • Place of Presentation
      下関
    • Related Report
      2011 Final Research Report
  • [Presentation] Low HDL-cholesterol is associated with stroke in elderly diabetic individuals2009

    • Author(s)
      Hayashi T, et al
    • Organizer
      19^<th> IAGG World Congress of Gerontology and Geriatric Paris
    • Related Report
      2011 Final Research Report
  • [Presentation] Depression, Quality of Life and Living will of postmenopausal elderly women in east asia2009

    • Author(s)
      Ina K, Hayashi T
    • Organizer
      19^<th> IAGG World Congress of Gerontology and Geriatric Paris
    • Place of Presentation
      Japan, Korea and China
    • Related Report
      2011 Final Research Report
  • [Presentation] 糖尿病合併心血管病危険因子の検討-日本人の脂質の寄与の年代差2009

    • Author(s)
      林登志雄, 他
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 本邦高齢女性の動脈硬化関連遺伝子変異病態解析の有用性2009

    • Author(s)
      伊奈孝一郎,林登志雄
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] グルコースとインシュリンの細胞老化と動脈硬化への作用2009

    • Author(s)
      林登志雄, 他
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 東アジア3カ国閉経後から後期高齢女性の精神、QOLの検討2009

    • Author(s)
      伊奈孝一郎,林登志雄, 他
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 老化及び老年医学研2007年度受賞者講演血管老化を標的とした一酸化窒素,活性酸素制御を介する動脈硬化退縮療法2009

    • Author(s)
      林登志雄
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] HDL regulates the risk of stroke in very elderly diabetic individuals-The change in the risk factors at various ages2009

    • Author(s)
      T. Hayashi, et al
    • Organizer
      The American Diabetes Association's 69th Scientific Sessions New Orleans
    • Related Report
      2011 Final Research Report
  • [Presentation] Biphsic effects of insulin on endothelial senescence2009

    • Author(s)
      K Ina, T. Hayashi, et al
    • Organizer
      The 10^<th> International Symposium on Mechanisms of Vasodiatation
    • Place of Presentation
      Matsushima, Miyagi
    • Related Report
      2011 Final Research Report
  • [Presentation] A new view of atheroslcerosis related pharmacogenetics based gene analysis in Japanese elderly women2009

    • Author(s)
      K Ina, T. Hayashi, et al
    • Organizer
      The 10^<th> International Symposium on Mechanisms of Vasodiatation
    • Place of Presentation
      Matsushima, Miyagi
    • Related Report
      2011 Final Research Report
  • [Presentation] 糖尿病罹患者における脳卒中リスクとしての脂質の影響.年齢による危険因子の変化-2009

    • Author(s)
      伊奈孝一郎,林登志雄, 他
    • Organizer
      第52回日本糖尿病学会学術集会
    • Place of Presentation
      大阪
    • Related Report
      2011 Final Research Report
  • [Presentation] 血管内皮細胞老化におけるグルコースとインシュリンの役割2009

    • Author(s)
      林登志雄, 他
    • Organizer
      第52回日本糖尿病学会学術集会
    • Place of Presentation
      大阪
    • Related Report
      2011 Final Research Report
  • [Presentation] シンポジウムNOとインスリン抵抗性-糖尿病・老化)グルコースとインスリンの細胞老化ストレスを介する動脈硬化への作用2009

    • Author(s)
      林登志雄
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] セミナー:シトルリン~ NO産生と動脈硬化予防への展望2009

    • Author(s)
      林登志雄
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] 閉経後高齢女性におけるラロキシフェンの有用性の検討-HRTからの移行例との比較試験成績から-2009

    • Author(s)
      伊奈孝一郎,林登志雄
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] HMG CoA還元酵素阻害剤は慢性透析患者にPleiotropic効果として、動脈硬化血管内皮機能を改善する2009

    • Author(s)
      伊奈孝一郎,林登志雄, 他
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] 日本人高齢女性における遺伝子変異解析に基づく、遺伝薬理学関連動脈硬化症の可能性の検討石塚麻子2009

    • Author(s)
      林登志雄, 他2名
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] IGF-1(インスリン様細胞成長因子)の動脈硬化症への影響について金谷りえ2009

    • Author(s)
      林登志雄
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] L-シトルリンの短期間摂取がヒトの血管弾性に及ぼす影響落合将之2009

    • Author(s)
      林登志雄, 他2名
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] エストロゲン及び一酸化窒素の老化シグナルへの影響平井寿子2009

    • Author(s)
      林登志雄, 他3名
    • Organizer
      第9回日本NO学術集会
    • Place of Presentation
      静岡
    • Related Report
      2011 Final Research Report
  • [Presentation] The role of glucose and insulin on endothelial senescence-The relation of diversity effect of insulin2009

    • Author(s)
      Hayashi T, et al
    • Organizer
      The American Geriatrics Society 2009 Annual Scientific Meeting
    • Place of Presentation
      Chicago, IL, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Vascular senescence and NO in asian elderererly.2008

    • Author(s)
      Hayashi T.
    • Organizer
      Symposium of Konkuk University
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-11-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] siRNAを用いた老化関連疾患の病態解明-RNA干渉2008

    • Author(s)
      林登志雄
    • Organizer
      第38回薬物活性シンポジウム
    • Place of Presentation
      徳島
    • Year and Date
      2008-10-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] HDL cholesterol is more important than glucose control in prevention of atherosclerotic diseases in Asian diabetic elderly.2008

    • Author(s)
      Hayashi T
    • Organizer
      Symposium 5th Congress of European Union Geriatric Medicine Society
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2008-09-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] インスリンの細胞老化ストレスを介する動脈硬化への作用2008

    • Author(s)
      林登志雄
    • Organizer
      第40回日本動脈硬化学会シンポジウム
    • Place of Presentation
      筑波
    • Year and Date
      2008-07-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] 動脈硬化症における加齢と性の役割-本邦閉経後女性の心血管病リスクの面から-2008

    • Author(s)
      林登志雄
    • Organizer
      第8回日本抗加齢医学会パドルセッション : 女性ホルモン補充療法をめぐる議論(招待講演)
    • Place of Presentation
      東京
    • Year and Date
      2008-05-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] LDL and HDL cholesterol might play more important role than glucose conirol in the prevention of ischemic cardiovascular disease in Japanese diabetic old and old.2008

    • Author(s)
      Hayashi T, (他3名1番目)
    • Organizer
      Annual Scientific Meeting Amaican Geriatrics Society
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-05-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] The effect of NO in endothelial senescence.2008

    • Author(s)
      Hayashi T, (他3名1番目)
    • Organizer
      Annual Sdentific Meeting American Geriatrics Society
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-05-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Interactions of glucose and insulin in regulation of replicative and stress-induced endothelial senescence

    • Author(s)
      Hayashi T
    • Organizer
      14^<th> International Congress of Endocrinology
    • Place of Presentation
      Kyoto
    • Related Report
      2011 Final Research Report
  • [Book] 疾患からみた薬理学改訂3版骨粗鬆症2011

    • Author(s)
      林登志雄,渡邉裕司
    • Related Report
      2011 Final Research Report
  • [Book] 疾患からみた薬理学改訂3版骨粗鬆症2011

    • Author(s)
      林登志雄
    • Publisher
      じほう社
    • Related Report
      2011 Annual Research Report
  • [Book] 骨粗鬆症2011

    • Author(s)
      林登志雄
    • Publisher
      じほう社
    • Related Report
      2010 Self-evaluation Report
  • [Book] 骨粗鬆症2011

    • Author(s)
      林登志雄
    • Publisher
      じほう社(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] Atherosclerosis and Aging. Nitric Oxide Biology and Pathobiology2010

    • Author(s)
      Hayashi T, Iguchi A, Ignarro LJ
    • Publisher
      Elsevier Co. Ltd.
    • Related Report
      2011 Final Research Report
  • [Book] これからの老年医学2009

    • Author(s)
      林登志雄,余澤雲,井口昭久
    • Total Pages
      316
    • Publisher
      中国語版昆明医学中央出版/名大出版社
    • Related Report
      2011 Final Research Report
  • [Book] Free radicals as atherosclerotic risk-The relation of NO2009

    • Author(s)
      Hayashi T
    • Publisher
      Elsevier Co. Ltd.(印刷中)
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] シトルリンとNO2009

    • Inventor(s)
      林登志雄, 他
    • Industrial Property Rights Holder
      林登志雄,名古屋大学他
    • Acquisition Date
      2009-10-10
    • Related Report
      2011 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi