| Project/Area Number |
20406010
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Aichi Medical University |
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Principal Investigator |
KIMURA Eisaku 愛知医科大学, 医学部, 教授 (70153187)
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| Co-Investigator(Kenkyū-buntansha) |
HIRAYAMA Kenji 長崎大学, 熱帯医学研究所, 教授 (60189868)
ITOH Makoto 愛知医科大学, 医学部, 教授 (90137117)
TAKAGI Hidekazu 愛知医科大学, 医学部, 講師 (90288522)
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| Research Collaborator |
MV Weerasooriya Ruhuna Univ., Faculty of Medicine(Sri Lanka), Professor
TC Yahathugoda Ruhuna Univ., Faculty of Medicine(Sri Lanka), Senior Lecturer
磯貝 芳徳 日本福祉大学, 情報社会科学学部, 教授
菊池 三穂子 長崎大学, 熱帯医学研究所, 講師
長岡 史晃 愛知医科大学, 医学部, 大学院生
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2009: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2008: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | フィラリア症 / 免疫診断 / 尿 / IgG4 / LAMP / 象皮病 / 国際研究者交流 / スリランカ / 尿ELISA |
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| Research Abstract |
An immunodiagnosis using urine samples(urine ELISA) has been found effective in finding out filaria-infected individuals in very low endemic areas. The method will be useful to confirm elimination of filariasis or detect its resurgence. A new urine-based, visual diagnosis(beads method) has also been developed. It can replace urine ELISA in areas where sophisticated equipment is not available. A LAMP method to detect filarial DNA in mosquito vectors has been developed. These new methods will help discover "hidden" endemic foci, and thus contribute greatly in the final stage of the elimination program.
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