| Project/Area Number |
20406028
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 海外学術 |
|---|
| Research Field |
Pediatric surgery
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
HIYAMA Eiso Hiroshima University, 自然科学研究支援開発センター, 教授 (00218744)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAJIRI Tatsuro 九州大学, 医学研究科, 准教授 (80304806)
OUE Takaharu 大阪大学, 医学研究科, 助教 (50314315)
KAMIMATSUSE Arata 広島大学, 病院, 病院助教 (90569881)
HISHIKI Tomoro 千葉大学, 大学院・医学研究院, 講師 (00375776)
IDA Koumei 東京大学, 医学部・附属病院, 准教授 (60313128)
YAMAOKA Hiroaki 広島大学, 病院, 講師 (90311810)
NISHIMURA Shinichiro 広島大学, 医歯薬学総合研究科, 准教授 (00228222)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
KONDO Satoshi 名古屋市立大学, 医学研究科, 講師 (50234935)
WATANABE Kenichiro 京都大学, 医学研究科, 講師 (20324634)
YANO Michihiro 秋田大学, 医学部, 助教 (40321997)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2010: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
|
|---|
| Keywords | 癌 / 医療・福祉 / 薬剤反応性 / トランスレーショナルリサーチ / 外科 / 小児 / 肝 / リスク分類 / 国際共同研究 / 副作用 / 小児肝がん / 肝芽腫 / 国際共同臨床試験 / 共通登録システム / 治療効果判定 / 共通データベース / 副作用評価 |
|---|
| Research Abstract |
We conducted overseas research, mainly in Europe (SIOPEL) and North America(COG), on cases of hepatoblastoma, which account for over 80% of all pediatric liver tumors.. In Japan, the rate of incidence was higher than in these countries, but the incidence of pathologically small undifferentiated tumors was lower.. According to the outcome of the patients, we stratified the hepatoblastoma patients into three risk groups : standard, intermediate, and high risks and proposed new treatment protocols for each group. We also built a new pathological classification scheme and registration database, to pave the way for international collaboration in infrastructure development for clinical trials.
|
