| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
In this study, we found knock down of CRMP family members causes developmental defect in cranial ganglia. By live observation, defect is caused by random alignment of neuronal cell bodies and axonogenetic region, and abnormal cellular migration. These defects were also caused by knock down of neuropilins and adherence molecules, and double knock down analysis implies these molecules are in a same genetic pathway.
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