Visualization of strategic localization of synaptic molecules
| Project/Area Number |
20500317
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
KAMASAWA Naomi National Institute for Physiological Sciences, 大脳皮質機能研究系, 特任助教 (50455218)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 脳・神経 / シナプス / 受容体 / チャネル / 電子顕微鏡 / レプリカ標識法 / グルタミン酸受容体 / カルシウムチャネル / 可視化 / 凍結割断レプリカ免疫コロイド金標識法 |
|---|
| Research Abstract |
Synaptic membrane molecules, glutamate receptors and calcium channels were ultrastructurally visualized in the calyx of Held synapse using freeze-fracture replica immunogold labeling methods. Presynaptic and postsynaptic components were synchronously localized to the synapses at the timing of the onset of hearing.
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Report
(4 results)
Research Products
(20 results)
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[Journal Article] Connexin45-Containing Neuronal Gap Junctions in Rodent Retina Also Contain Connexin36 in Both Apposing Hemiplaques, Forming Bihomotypic Gap Junctions, with Scaffolding Contributed by Zonula Occludens-12008
Author(s)
Li, N Kamasawa, C Ciolofan, CO Olson, S Lu, KGV Davidson, T Yasumura, R Shigemoto, JE Rash, JI Nagy
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Journal Title
The Journal of Neuroscience 28巻
Pages: 9769-9789
Related Report
Peer Reviewed
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[Journal Article] Connexin45-Containing Neuronal Gap Junctions in Rodent Retina Also Contain Connexin36 in Both Apposing Hemiplaques, Forming Bihomotypic Gap Junctions, with Scaffolding Contributed by Zonula Occludens-12008
Author(s)
X Li, N Kamasawa, C Ciolofan, CO Olson, S Lu, KGV Davidson, T Yasumura, R Shigemoto, JE Rash, JI Nagy
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Journal Title
The Journal of Neuroscience 28
Pages: 9769-9789
Related Report
Peer Reviewed
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