| Project/Area Number |
20500323
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Kanazawa University |
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Principal Investigator |
KOIZUMI Keita Kanazawa University, 子どものこころの発達研究センター, 特任准教授 (70377406)
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| Co-Investigator(Kenkyū-buntansha) |
HIGASHIDA Haruhiro 金沢大学, 医学系, 教授 (30093066)
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| Co-Investigator(Renkei-kenkyūsha) |
MUNESUE Toshio 金沢大学, 子どものこころの発達研究センター, 特任教授 (50293353)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 脳発達障害 / 遺伝子スクリーニング / 発達障害 / 分子遺伝学 / RNAi |
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| Research Abstract |
The final goal of this study is to identify new genes that are associated with autism/developmental disorders. For this purpose, we screened around 8800 genes in Drosophila as the first step and the second step studies in mice picked up 7 candidate genes, possibly, related to human developmental disorders. Our clinical study finally succeeded to figure out ones of these genes, RoboIII/IV are associated with autism.
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