Protein modification mechanism regulating synchronization/desynchronization of circadian system
| Project/Area Number |
20500344
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Toho University |
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Principal Investigator |
TAMARU Teruya Toho University, 医学部, 講師 (80291706)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 分子・細胞・神経生物学 / 細胞内情報伝達 / サーカディアンリズム / circadian rhythm / Phosphorylation / transcription factor / clock gene / signal transduction / casein kinase / bioluminescence / stress response / circadian clock / phosphorylation / protein kinase / live cell imagin / Casein kinase / SCN / Bioluminescence |
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| Research Abstract |
We elucidated circadian CK2-mediated BMAL1 (a core circadian transcription factor) phospholylation essential protein modification for circadian system.
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Report
(4 results)
Research Products
(32 results)
