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Development of optical imaging system with the emphasis of causality of cell activity

Research Project

Project/Area Number 20500393
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionKagoshima University

Principal Investigator

WANG Gang  Kagoshima University, 理工学研究科(工学系), 教授 (40274831)

Co-Investigator(Kenkyū-buntansha) SUZUKI Wataru  鹿児島大学, 工学部, 助教 (80332336)
Co-Investigator(Renkei-kenkyūsha) OKAMURA Junya  鹿児島大学, 理工学研究科, 助教 (30447594)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords生体計測 / 脳神経活動 / イメージング / 光学的計測法 / 視覚 / 物体認知 / 光学的信号 / 光計測 / 相関 / 内因性光計測 / 視覚野
Research Abstract

As an association cortex, inferotemporal cortex is the final stage of the ventral cortical pathway which is critical for object recognition and object discrimination. To investigate the functional organization of the cortical area, the optical imaging based on intrinsic signals is thought to be a powerful technique. However, although the optical imaging simultaneously records the activity for a large population of cells in a relative wide cortical area, the method to analyze the causal relationship across the local regions in the imaged area is not yet available. In the present study, we have succeeded in the separation between the component of optical signal induced by the presentation of the stimulus and that independent on the stimulus presentation, and proposed a method to emphasize the activity relationship.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (32 results)

All 2011 2010 2009 2008 Other

All Journal Article (14 results) (of which Peer Reviewed: 13 results) Presentation (18 results)

  • [Journal Article] 側頭葉下部皮質における観察角度に依らない物体認識の表現2011

    • Author(s)
      岡村純也、池尻祐大、山口玲欧奈、王鋼
    • Journal Title

      電子情報通信学会信学技報

      Volume: MBE2010-87 Pages: 45-50

    • NAID

      10027801393

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Three-dimensional object recognition learning alters an early ERP component of N1.2010

    • Author(s)
      Gang Wang, Junichi Bingo.
    • Journal Title

      Clinical Neurophysiology 121

      Pages: 1473-1480

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] View-invariant object recognition ability develops after discrimination, not mere exposure, at several viewing angles.2010

    • Author(s)
      Wakayo Yamashita, Gang Wang, Keiji Tanaka.
    • Journal Title

      European Journal of Neuroscience 31

      Pages: 327-335

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional object recognition learning alters an early ERP component N12010

    • Author(s)
      G.Wang, J.Bingo
    • Journal Title

      Clinical Neurophysiology

      Volume: 121 Pages: 1473-1480

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] View-invariant object recognition ability develops after discrimination, not mere exposure, at several viewing angles2010

    • Author(s)
      W.Yamashita, G.Wang, K.Tanaka
    • Journal Title

      European Journal of Neuroscience

      Volume: 31 Pages: 327-335

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] View-invariant object recognition ability develops after discrimination, not mere exposure, at several viewing angles2010

    • Author(s)
      W.Yamashita, G.Wang, K.Tanaka.
    • Journal Title

      European Journal of Neuroscience 31

      Pages: 327-335

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extraction of stimulus-selective intrinsic optical signals from the cat visual cortex.2009

    • Author(s)
      永井翠, 王鋼
    • Journal Title

      IEEJ Transactions on Electrical and Electronic Engineering 4

      Pages: 696-703

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 大脳皮質における内因性光学的反応のダイナミクスの解析法2009

    • Author(s)
      永井翠、大塚俊幸、王鋼
    • Journal Title

      生体医工学 47

      Pages: 176-183

    • NAID

      10025974239

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extraction of stimulus-selective intrinsic optical signals from the cat visual cortex2009

    • Author(s)
      永井翠, 王鋼
    • Journal Title

      IEEJ Transactions on Electrical and Electronic Engineering 4

      Pages: 696-703

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 大脳皮質における内因性光学的反応のダイナミクスの解析法2009

    • Author(s)
      永井翠, 大塚俊幸, 王鋼
    • Journal Title

      生体医工学 47

      Pages: 176-183

    • NAID

      10025974239

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 大脳皮質における内因性光学的反応のダイナミクスの解析法2009

    • Author(s)
      永井翠, 大塚俊幸, 王鋼
    • Journal Title

      生体医工学 47(印刷中)

    • NAID

      10025974239

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 観察角度をまたいだ物体弁別の学習に対する内挿角画像呈示の促進作用2008

    • Author(s)
      山下和香代、林潤一、竹原慎太郎、王鋼
    • Journal Title

      生体医工学 46

      Pages: 514-521

    • NAID

      110007022770

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Orientation dependency of intrinsic optical signal dynamics in cat area 18.

    • Author(s)
      Midori Nagai, Junya Okamura, Gang Wang
    • Journal Title

      NeuroImage in press.

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] ネコ第二次視覚野における内因性光学的信号の時間的変化とその傾き方位の依存性

    • Author(s)
      永井翠、岡村純也、井上雄太、王鋼
    • Journal Title

      生体医工学 49,in press

    • NAID

      130004947483

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 側頭葉下部皮質における三次元物体の表現2011

    • Author(s)
      岡村純也、王鋼
    • Organizer
      平成22年度日本生体医工学会九州支部学術講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 主成分分析法(PCA)を用いた内因性光学的信号抽出法の提案2011

    • Author(s)
      地頭薗美紀、内村華奈美、王鋼
    • Organizer
      平成22年度日本生体医工学会九州支部学術講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 三次元物体弁別学習に伴う事象関連電位の変化2011

    • Author(s)
      徳留亘、東慎士、王鋼
    • Organizer
      平成22年度日本生体医工学会九州支部学術講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 三次元物体弁別学習に伴う事象関連電位の変化2011

    • Author(s)
      徳留亘、東慎士、王鋼
    • Organizer
      平成22年度日本生体医工学会大会九州支部講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 主成分分析法(PCA)を用いた内因性光学的信号抽出法の提案2011

    • Author(s)
      地頭薗美紀、内村華奈美、王鋼
    • Organizer
      平成22年度日本生体医工学会大会九州支部講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 側頭葉下部皮質における三次元物体の表現2011

    • Author(s)
      池尻祐大、山口玲欧奈、岡村純也、王鋼
    • Organizer
      平成22年度日本生体医工学会大会九州支部講演会
    • Place of Presentation
      福岡
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 側頭葉下部皮質における観察角度に依らない物体認識の表現2011

    • Author(s)
      岡村純也、池尻祐大、山口玲欧奈、王鋼
    • Organizer
      MEとバイオサイバネティックス研究会
    • Place of Presentation
      鹿児島
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] ネコ視覚野皮質における内因性光学的信号の時間経過の方位依存性2010

    • Author(s)
      岡村純也、永井翠、井上祐太、王鋼
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Discrimination of individual images at several viewing angles contributes to the development of view-invariant object recognition2010

    • Author(s)
      岡村純也、山下和香代、潤美紀、池尻祐大、王鋼
    • Organizer
      第49回日本生体医工学会大会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] Discrimination of individual images at several viewing angles contribute to the development of view-invariant object recognition2010

    • Author(s)
      岡村純也、山下和香代、潤美紀、池尻祐大、王鋼
    • Organizer
      第49回日本生体医工学会大会
    • Place of Presentation
      大阪
    • Related Report
      2010 Annual Research Report
  • [Presentation] 第一次視覚野細胞の刺激選択性と内因性光学的信号の時間的特徴2009

    • Author(s)
      大塚俊幸、永井翠、王鋼
    • Organizer
      平成20年度日本生体医工学会九州支部学術講演会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-07
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚野細胞の刺激選択性と内因性光学的信号の時間的特徴2009

    • Author(s)
      大塚俊幸, 永井翠, 王鋼
    • Organizer
      平成20年度日本生体医工学会九州支部学術講演会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 視覚野方位選択性機能マップに対する周辺視野刺激の修飾作用2009

    • Author(s)
      永井翠、廣野悠太、岡村純也、王鋼
    • Organizer
      視覚フォーラム
    • Place of Presentation
      鹿児島
    • Related Report
      2010 Final Research Report
  • [Presentation] 観察角度に依存しない物体認識の形成における積極的物体弁別と受動的物体観察2009

    • Author(s)
      岡村純也、山下和香代、潤美紀、王鋼
    • Organizer
      視覚フォーラム
    • Place of Presentation
      鹿児島
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚野方位選択性機能マップに対する周辺視野刺激の修飾作用2009

    • Author(s)
      永井翠, 廣野悠太, 岡村純也, 王鋼
    • Organizer
      視覚フォーラム
    • Place of Presentation
      鹿児島大学(鹿児島県)
    • Related Report
      2009 Annual Research Report
  • [Presentation] ネコ第一次視覚野における内因性光学的反応評価方法の開発2008

    • Author(s)
      永井翠、大塚俊幸、王鋼
    • Organizer
      生体医工学シンポジウム2008
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] 観察角度をまたいだ物体弁別の学習に対する内挿角画像呈示の促進作用2008

    • Author(s)
      山下和香代、林潤一、竹原慎太郎、王鋼
    • Organizer
      生体医工学シンポジウム2008
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] A method for the construction of cortical functional map based on the intrinsic optical signals2008

    • Author(s)
      M. Nagai, T. Otsuka, G. Wang
    • Organizer
      38th Annual Meeting, Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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