| Project/Area Number |
20500401
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Kanagawa Institute of Technology |
|---|
Principal Investigator |
MATSUO Takashi Kanagawa Institute of Technology, 創造工学部, 教授 (00165771)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
WATANABE Shin-Ichi 神奈川工科大学, 創造工学部, 准教授 (30333157)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
|
|---|
| Keywords | 脳血流 / 中大脳動脈 / 超音波ドップラ / 姿勢変換 / 運動負荷 / 血流波形 / メンタルストレス |
|---|
| Research Abstract |
The blood flow velocities in the middle cerebral artery (MCA) were measured under exercise as well as posture change using the transcranial Doppler ultrasound velocimeter. The peak-systolic velocity was found to rise markedly under exercise, while the end-diastolic velocity tended to remain at resting value. The relationship between peak-systolic velocity and systolic blood pressure, and that between peak-systolic velocity and heart rate were found to show statistically significant correlation. The mean MCA blood velocity also showed significant correlation with mean arterial pressure and heart rate. The fluctuations of velocity and resistance index were calculated in order to evaluate the hemodynamic load on the vessel wall ; these also increased markedly under exercise. Such hemodynamic changes in activity might be important in understanding the genesis of vascular diseases as well as the physiology of cerebral circulation.
|
