| Project/Area Number |
20500405
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
NAGAI Akiko Tokyo Medical and Dental University, 生体材料工学研究所, 准教授 (40360599)
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| Co-Investigator(Kenkyū-buntansha) |
YAMASHITA Kimihiro 東京医科歯科大学, 生体材料工学研究所, 教授 (70174670)
NAKAMURA Miho 東京医科歯科大学, 生体材料工学研究所, 助教 (40401385)
OU Gi 東京医科歯科大学, 生体材料工学研究所, 助教 (60451944)
TANAKA Yumi 東京医科歯科大学, 生体材料工学研究所, 助教 (00436619)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 再生医工学材料 / バイオセラミックス / 分極 / アパタイト / チタニア / 血管リモデリング / マイクロアーク陽極酸化法 / 生体親和性 / 光触媒 / 分極バイオセラミックス / 医用材料 / 再生医療 / 分極ハイドロキシアパタイト |
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| Research Abstract |
We fabricated new hybrid composite materials based on polarized bioceramics. Intimal hyperplasia in injured arteries of rabbit suppressed and phenotypic conversion of smooth muscle cells stimulated in response to electrical signals which were generated by the polarized materials in this study. We expect that the new materials should be useful as vascular regenerative materials with long-lasting use and low cost.
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