Elucidation of the Mechanism of Ischemic Mitral Regurgitation by Assessment of Mitral complex Torsion

• Project/Area Number: 20500427
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical systems
• Research Institution: Juntendo University
• Principal Investigator: MASAO Daimon Juntendo University, 医学部, 准教授 (80343094)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2009: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 僧帽弁複合体 / 僧帽弁逆流 / 画像診断 / 3次元心エコー法 / 組織ドプラ法 / 心エコー図 / 機能的僧帽弁逆流 / 画像解析

Research Abstract

Ischemic mitral regurgitation (MR) is functional MR caused by left ventricular geometrical changes. We exploit 3D echocardiography and 2D speckle tracing imaging to disclose the relationship between twisting motion of the mitral complex and functional MR

Research Products

• [Journal Article] Echocardiographic Assessment of the Effects of Mitral Valve Repair on Mitral Valve Geometry in Rheumatic Mitral Stenosis. (2010)
  • Author(s): Makinae H, Daimon M, Tambara K, Miyazaki S, Iwamura H, Yamasaki M, Inaba H, Yamamoto T, Daida H, Amano H
  • Journal Title: J Heart Valve Dis 19(4) Pages: 427-33
  • Peer Reviewed
• [Journal Article] Dynamic Change of Mitral Annular Geometry and Motion in Ischemic Mitral Regurgitation Assessed by A Computerized 3D Echo Method. (2010)
  • Author(s): Daimon M, Saracino G, Fukuda S, Koyama Y, Kwan J, Song JM, Agler DA, Gillinov AM, Thomas JD, Shiota T
  • Journal Title: Echocardiography 27(9) Pages: 1069-77
  • Peer Reviewed
• [Journal Article] Reconsiderations of Mitral Stenosis : Rheumatic Mitral Valve Repair and the Wilkins Score. (2010)
  • Author(s): Makinae H, Daimon M, Tambara K, Miyazaki S, Iwamura H, Inaba H, Yamamoto T, Daida H, Amano H
  • Journal Title: J Echocardiogr 8 Pages: 106-111
  • Peer Reviewed
• [Journal Article] Dynamic Change of Mitral Annular Geometry and Motion in Ischemic Mitral Regurgitation Assessed by A Computerized 3D Echo Method. (2010)
  • Author(s): Daimon M, et al.
  • Journal Title: Echocardiography Volume: 27 Pages: 1069-77
  • Peer Reviewed
• [Journal Article] Echocardiographic Assessment of the Effects of Mitral Valve Repair on Mitral Valve Geometry in Rheumatic Mitral Stenosis. (2010)
  • Author(s): Makinae H, Daimon M, et al.
  • Journal Title: J Heart Valve Dis Volume: 19 Pages: 427-433
  • Peer Reviewed
• [Journal Article] Reconsiderations of Mitral Stenosis : Rheumatic Mitral Valve Repair and the Wilkins Score (2010)
  • Author(s): Makinae H, Daimon M, et al.
  • Journal Title: J Echocardiogr Volume: 8 Pages: 106-111
  • Peer Reviewed
• [Journal Article] 心エコー図から非同期収縮を識る (2010)
  • Author(s): 宮崎彩記子、大門雅夫
  • Journal Title: Heart view Volume: 14 Pages: 54-61
• [Journal Article] 僧帽弁閉鎖不全症:症例に基づいた非外科的治療の進め方 (2010)
  • Author(s): 大門雅夫
  • Journal Title: Heart View Volume: 14 Pages: 1370-1373
• [Journal Article] Dynamic Change of Mitral Annular Geometry and Motion in Ischemic Mitral Regurgitation Assessed by A Computerized 3D Echo Method (2010)
  • Author(s): Daimon M, et al.
  • Journal Title: Echocardiography (In press)
  • Peer Reviewed
• [Journal Article] Echocardiographic Assessment of the Effects of Mitcral Valve Repair on Mitral Valve Geometry in Rheumatic Mitral Stenosis (2010)
  • Author(s): Makinae H, Daimon M, et al.
  • Journal Title: J Heart Valve Dis (In press)
  • Peer Reviewed
• [Journal Article] Global Longitudinal Strain in Relation to the Severity of Aortic Stenosis : A Two-dimensional Speckle-tracking Study.
  • Author(s): Miyazaki S, Daimon M, et al.
  • Journal Title: Echocardiography Volume: (In press)
  • Peer Reviewed
• [Presentation] 僧帽弁逆流重症度評価のピットフォール (2011)
  • Author(s): 大門雅夫
  • Organizer: 第13回エコーウインターセミナー
  • Place of Presentation: 軽井沢
• [Presentation] 心エコー図による心機能評価:最近のトピック (2010)
  • Author(s): 大門雅夫
  • Organizer: 第5回ハートセンターフォーラム
  • Place of Presentation: 川崎
  • Year and Date: 2010-10-04
• [Presentation] 症例呈示によるMRの診断、治療戦略、タイミング (2010)
  • Author(s): 大門雅夫
  • Organizer: Cardiologist valve workshop
  • Place of Presentation: 東京
  • Year and Date: 2010-06-27
• [Presentation] 症例呈示による僧帽弁逆流の診断、治療戦略、タイミング (2010)
  • Author(s): 大門雅夫
  • Organizer: Cardiologist valve workshop
  • Place of Presentation: 東京
  • Year and Date: 2010-06-27
• [Presentation] Impact of left ventricular sphericity index in the commissural-commisural direction on functional mitral regurgitation assessed by 2D echocardiography. (2010)
  • Author(s): Gakuto Yozu, Masao Daimon, Sakiko Miyazaki, Yoko Koiso, Yuko Onishi, Atsushi Amano, Hiromasa Suzuki, Hiroyuki Daida
  • Organizer: 第74回日本循環器病学会学術集会
  • Place of Presentation: 京都
• [Presentation] 機能的僧帽弁逆流における僧帽弁複合体のねじれ運動:リアルタイム3次元心エコーによる検討 (2010)
  • Author(s): 大門雅夫、宮崎彩記子、小磯容子、松浦優子、鈴木宏昌、代田浩之
  • Organizer: 第21回日本心エコー図学会学術集会
  • Place of Presentation: 札幌
• [Presentation] 僧帽弁に対するカテーテル治療と心エコー図 (2010)
  • Author(s): 大門雅夫
  • Organizer: 第12回エコーウインターセミナー
  • Place of Presentation: 軽井沢
• [Presentation] Twisting Motion of the Mitral Complex Assessed by Real-time 3-dimensional Echocardiography : Comparison between Normal Subjects and Functional Mitral Regurgitation (2010)
  • Author(s): M Daimon, S Miyazaki, Y Koiso, Y Onishi, S Chiang, H Suzuki, H, Daida
  • Organizer: American Heart Association Scientific sessions 2010
  • Place of Presentation: Chicago, Illinois, U.S.A
• [Presentation] Impact of left ventricular sphericity index in the commissural-commisural direction on functional mitral regurgitation assessed by 2D echocardiography. (2010)
  • Author(s): Daimon M, et al.
  • Organizer: Valves in the Heart of the Big Apple VI : Evaluation and management of Valvular Heart Disease 2010
  • Place of Presentation: New York.U.S.A
• [Presentation] When and How Aortic Stenosis is initially detected? : Retrospective Analysis in Japanese modern practice. (2010)
  • Author(s): Miyazaki S, Daimon M, et al.
  • Organizer: Valves in the Heart of the Big Apple VI : Evaluation and management of Valvular Heart Disease 2010
  • Place of Presentation: New York.U.S.A
• [Presentation] Twisting Motion of the Mitral Complex Assessed by Real-time 3-dimensional Echocardiography : Comparison between Normal Subjects and Functional Mitral Regurgitation. (2010)
  • Author(s): Daimon M, et al.
  • Organizer: American Heart Association Scientific sessions 2010
  • Place of Presentation: Chicago, Illinois, U.S.A
• [Presentation] 胎児から出生における左室捻れ運動:2D speckle tracking imagingによる検討 (2010)
  • Author(s): 松浦優子、大門雅夫, ら
  • Organizer: 第58回日本心臓病学会学術集会
  • Place of Presentation: 東京
• [Presentation] 僧帽弁はねじれるのか? 正常例と機能性閉鎖不全の比較 (2009)
  • Author(s): 大門雅夫、宮崎彩記子、小磯容子、大西優子、鈴木宏昌、代田浩之
  • Organizer: 第5回心筋会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-04
• [Presentation] 僧帽弁はねじれるのか?正常例と機能性閉鎖不全の比較 (2009)
  • Author(s): 大門雅夫, ら
  • Organizer: 第5回心筋会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-04
• [Presentation] Impact of Left Ventricular Sphericity in the Commissura-commissural direction on Functional Mitral Regurgitation Assessed by 2D Echocardiography (2009)
  • Author(s): M Daimon, G Yozu, S Miyazaki, Y Koiso, Y Onishi, H Suzuki, T Yamamoto, A Amano, H, Daida
  • Organizer: Valves in the Heart of the Big Apple VI : Evaluation and management of Valvular Heart Disease 2010
  • Place of Presentation: New York, U.S.A.
• [Presentation] 僧帽弁狭窄症に対し弁形成を施行した6症例の検討 (2009)
  • Author(s): 宮崎彩記子, 大門雅夫, ら
  • Organizer: 第20回日本心エコー図学会学術集会
  • Place of Presentation: 高松
• [Presentation] 僧帽弁狭窄症における僧帽弁形成術:心エコー図による評価 (2009)
  • Author(s): 大門雅夫, ら
  • Organizer: 第57回日本心臓病学会学術集会
  • Place of Presentation: 札幌
• [Book] 僧帽弁閉鎖不全症(症例に基づいた非外科的治療の進め方 14) (2010)
  • Author(s): 大門雅夫
  • Publisher: Heart View
• [Book] Heart Beat 2010 Autumn.(虚血性僧帽弁閉鎖不全症における外科的介入の至適時期とEtiology-specificな治療戦略の重要性)
  • Author(s): 大門雅夫
  • Publisher: Edwards Lifesicence
• [Remarks] ホームページ等