| Project/Area Number |
20500453
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
|
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| Research Institution | Kagoshima University |
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Principal Investigator |
OHWATASHI Akihiko Kagoshima University, 医学部, 助教 (30295282)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Satoshi 鹿児島大学, 医学部歯学部附属病院, 講師 (00343369)
YOSHIDA Akira 鹿児島大学, 医歯学総合研究科, 助教 (40347109)
KAWAHIRA Kazumi 鹿児島大学, 医歯学総合研究科, 教授 (20117493)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | マイクロダイアリシス / 神経伝達物質 / 脳の可塑性 / 運動療法 / 機能回復 |
|---|
| Research Abstract |
Extracellular concentrations of monoamines were investigated in the striatum and hippocampus before, during, and after treadmill exercise using microdialysis technique. It was found that serotonin and norepinephrine levels were increased during treadmill running and then returned to baseline levels ; however, dopamine levels peaked after treadmill exercise. Serotonin levels were increased in the hippocampus during treadmill running after 1 week of treadmill exercise.
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