The effects of frequency and duration of exercise on the differentiation and miniaturization of adipocyte and the secretion of adiponectin
| Project/Area Number |
20500627
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Keio University |
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Principal Investigator |
KIMURA Masaki Keio University, 薬学部, 講師 (40383666)
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| Research Collaborator |
SHINOZAKI Tomokazu 慶應義塾大学, 大学院・薬学研究科, 後期博士過程
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 肥満 / 運動療法 / 食事療法 / 脂肪細胞 / アディポネクチン / 運動 / アディポサイトカイン |
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| Research Abstract |
Obese rats were randomly assigned to either the 2 (17 to 19-week-old, everyday) or 4 (15 to 19-week-old, about every two day) weeks voluntary exercise or control group. Compared to 2 weeks exercise, 4 weeks exercise promoted the downsizing of adipocyte and provided the weak reduction in the value of the blood adiponectin concentration. These results suggested that the low frequency and long duration exercise therapy is more effective for the cellularity of adipocyte and maintenance of blood adiponectin concentration compared to the high frequency and short duration exercise therapy.
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Report
(4 results)
Research Products
(24 results)
