Basic research on metabolic syndrome improvement by anti-obesity peptide administering and therapeutic exercise
| Project/Area Number |
20500634
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Hoshi University |
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Principal Investigator |
TAKENOYA Fumiko Hoshi University, 薬学部, 講師 (30234412)
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| Co-Investigator(Kenkyū-buntansha) |
KAGEYAMA Haruaki 昭和大学, 医学部, 助教 (00433839)
SUZUKI Tsutomu 星薬科大学, 薬学部, 教授 (90130757)
塩田 清二 昭和大学, 医学部, 教授 (80102375)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIBA Kanako 昭和大学, 医学部, 助教 (40551263)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 抗肥満ペプチド / 運動療法 / エネルギー代謝 / 肥満改善 / ラット / メタボリック / 高次脳 / 機能形能解析 / 機能形態解析 / GALP(ガラニン様ペプチド) / ニューロン |
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| Research Abstract |
The intranasal infusion of Galanin-like peptide decreased both food intake and body weight in the obese mice. These results suggest that intranasal infusion of GALP is an effective route to exert its effect as an anti-obesity drug and therapeutic exercise.
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Report
(4 results)
Research Products
(109 results)
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[Journal Article] Neuropeptide W : An Anorectic Peptide Regulated by Leptin and Metabolic State.2010
Author(s)
DATE Y., MONDAL MS., KAGEYAMA H., GHAMARI-LANGROUDI M., TAKENOYA F., YAMAGUCHI H., SHIMOMURA Y., MORI M., MURAKAMI M., SHIODA S., CONE RD., MAKAZATO M
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Journal Title
Endocrinology 151
Pages: 2200-2210
Related Report
Peer Reviewed
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[Journal Article] Neuropeptide W is expressed in the noradrenalin-containing cells in the rat adrenal medulla.2008
Author(s)
SEKI M., KAGEYAMA H., TAKENOYA F., HIRAYAMA M., KINTAKA Y., INOUE S., MATSUNO R., ITABASHI K., DATE Y., NAKAZATO M., SHIODA S.
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Journal Title
Regul Pept 145
Pages: 147-152
Related Report
Peer Reviewed
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