| Project/Area Number |
20500736
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Seinan Jo Gakuin University |
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Principal Investigator |
TAGAWA Tatsuya Seinan Jo Gakuin University, 保健福祉学部, 教授 (50347142)
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| Co-Investigator(Renkei-kenkyūsha) |
YAGI Yasuo 西南女学院大学, 保健福祉学部, 教授 (80200476)
INAKI Mitsuharu 西南女学院大学, 保健福祉学部, 教授 (20261787)
UEDA Shinichiro 琉球大学, 大学院・医学研究科, 教授 (80285105)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 血管内皮機能 / メタボリックシンドローム / 栄養学的介入 / 動脈硬化予防 / アンチエイジング |
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| Research Abstract |
The aim of the present study was to examine whether long-term treatment of L-arginine also improves endothelial function in human forearms. Forearm blood flow (FBF) was measured by strain gauge plethysmography in nine healthy women, before and four weeks after oral treatment with L-arginine (2.5 g/day). FBF was measured during reactive hyperemia (RH). The long-term treatment with L-arginine significantly improved total reactive hyperemic flow (flow debt repayment) (P < 0.01). Our results suggest that L-arginine treatment may increase NO production in endothelium during reactive hyperemia in human forearm vessel.
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