Theoretical Study on Memory and Cognitive Functions in Hippocampus and Dendritic Information Integration
Project/Area Number |
20509001
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Sensitivity informatics/Soft computing
|
Research Institution | The University of Tokyo |
Principal Investigator |
OMORI Toshiaki 東京大学, 大学院・新領域創成科学研究科, 助教 (10391898)
|
Project Period (FY) |
2008 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,120,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
Keywords | 海馬体 / 樹状突起 / 記憶認知機能 / 位相応答曲線 / 膜特性 / 数理モデル / 情報表現 / 情報統合 / 海馬システム / 記憶認知システム / 確率的時系列解析 / メキシカンハット型相互作用 / 連想記憶モデル / 情報統計力学 / 非線形動力学 / 顔認知システム / 記憶機能 / 認知機能 / 海馬CAI / 情報統合機序 / 数理生理学 / 理論神経科学 / 海馬 / 神経細胞 / 神経ダイナミクス / カルマンフィルタ / データ同化 / シナプス統合 / ニューラルネットワーク |
Research Abstract |
In this study, we performed theoretical studies using mathematical models in order to investigate relation between dendritic information integration and neuronal information processing such as memory and cognitive functions in hippocampal formation. We showed by analysis and numerical simulations that the impact of sensory inputs given to distal dendrite on somatic response is significantly enhanced by effect of spatial structure of electrical properties over dendrite. Furthermore, we performed theoretical studies using mathematical model for spatial cognition function, one for memory function, and one for information representations of both face angle and face identity. We also clarified an analytical relation between phase response curve and neuronal membrane properties.
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Report
(6 results)
Research Products
(169 results)