The development of novel bioactive compounds from the nematocysts.
| Project/Area Number |
20510197
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Living organism molecular science
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| Research Institution | Tokyo University of Marine Science and Technology |
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Principal Investigator |
NAGAI Hiroshi Tokyo University of Marine Science and Technology, 海洋科学部, 教授 (50291026)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 生物活性物質 / 海洋天然物化学 / ウンバチイソギンチャク / 刺胞 / ポリペプチド / 遺伝子解析 / 質量分析 / トリプシンインヒビター / 刺胞動物 / アカクラゲ / 溶血活性 / フォスフォリパーゼA2 / リゾ型リン脂質 / ヒメイソギンチャク / タンパク質毒素 / アミノ酸・次配列 / 塩基配列 |
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| Research Abstract |
The screening of the novel bioactive compounds were accomplished on some cnidarians and isolated nematocysts. We have succeeded in the isolation and characterization of some new bioactive proteins and small molecular weight compounds. A new actinoporin toxin was isolated and characterized from the sea anemone Anthopleura asiatica. Furthermore, a new Kunitz type protease inhibitor protein was characterized from the sea anemone Phyllodiscus semoni.
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Report
(4 results)
Research Products
(96 results)
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[Presentation] Bioactive screening of deep-sea jellyfish2008
Author(s)
Takenori Kawabata, Minoru Kitamura, Dhugal J Lindsay, Satoshi Konishi, Jun Nishikawa, Shuhei Nishida, Hiroshi Nagai
Organizer
World Fisheries Congress 2008.
Place of Presentation
パシフィコ横浜(横浜、国際学会)
Year and Date
2008-10-22
Related Report
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