Analytical Model for Protein Folding
| Project/Area Number |
20540398
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biophysics/Chemical physics
|
|---|
| Research Institution | Meisei University |
|---|
Principal Investigator |
SUZUKI Yoko Meisei University, 理工学部, 准教授 (70342631)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | 生物物理 / 統計力学 / 物性基礎論 / 蛋白質 / 特性基歴理論 / 蛋白質フォールディング |
|---|
| Research Abstract |
In studying protein folding mechanism from analytical point of view, we introduce a model based on a Gaussian filament with an attractive force between a pair of residues forming a contact in the folded state and a repulsive force between any pairs of residues. By using this model, we estimate effects of the geometrical factors caused by a specific interaction based on a native structure and a non-specific interaction upon the folding mechanism.
|
Report
(4 results)
Research Products
(15 results)
