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Analytical Model for Protein Folding

Research Project

Project/Area Number 20540398
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics/Chemical physics
Research InstitutionMeisei University

Principal Investigator

SUZUKI Yoko  Meisei University, 理工学部, 准教授 (70342631)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords生物物理 / 統計力学 / 物性基礎論 / 蛋白質 / 特性基歴理論 / 蛋白質フォールディング
Research Abstract

In studying protein folding mechanism from analytical point of view, we introduce a model based on a Gaussian filament with an attractive force between a pair of residues forming a contact in the folded state and a repulsive force between any pairs of residues. By using this model, we estimate effects of the geometrical factors caused by a specific interaction based on a native structure and a non-specific interaction upon the folding mechanism.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (15 results)

All 2011 2010 2009 2008 Other

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (10 results) Remarks (1 results)

  • [Journal Article] An semi-analytical description of protein folding that incorporates detailed geometrical information2011

    • Author(s)
      Yoko Suzuki, Jeffery K. Noel, Jose N. Onuchic
    • Journal Title

      J.Chem.Phys. 134

      Pages: 245101-245101

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] An analytical Model for Protein folding2008

    • Author(s)
      Yoko Suzuki, Jeffery K. Noel, Jose N. Onuchic
    • Journal Title

      Proc.Of the International Symposium on Frontiers of Computational Science 2009 (FCS2009)(ed. By Y.Kaneda, M.Sasai, K Tachibana)(ISBN:978-4-9904336-0-4) (CD-ROM)

      Pages: 95-101

    • Related Report
      2010 Final Research Report
  • [Journal Article] An Analytical Model for Protein Folding2008

    • Author(s)
      Yoko Suzuki, JeffK. Noel, Jose N. Onuchic
    • Journal Title

      Proc. of the International Symposium on Frontiers of Computational Science 2009 (FCS2009), ed. by Y. Kaneda, M. Sasai, and Kanta Tachibana (CD-ROM)(ISBN : 978-4-9904336-0-4)

      Pages: 95-101

    • Related Report
      2008 Annual Research Report
  • [Journal Article] An semi-analytical description of protein folding that incorporates detailed geometrical information

    • Author(s)
      Yoko Suzuki, Jeff K.Noel, Jose N.Onuchic
    • Journal Title

      Journal of Chemical Physics

      Volume: (accepted)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 解析的モデルを用いた蛋白質フォールディング2010

    • Author(s)
      鈴木陽子
    • Organizer
      日本物理学会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Analytical Model for Protein Folding improved by introducing topological factors2010

    • Author(s)
      鈴木陽子
    • Organizer
      日本生物物理学会
    • Place of Presentation
      東北大学
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築2010

    • Author(s)
      鈴木陽子
    • Organizer
      日本物理学会
    • Place of Presentation
      岡山大学
    • Year and Date
      2010-03-21
    • Related Report
      2010 Final Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築2010

    • Author(s)
      鈴木陽子, Jeff K.Noel, Jose N.Onuchic
    • Organizer
      日本物理学会(第65回年次大会)
    • Place of Presentation
      岡山大学
    • Year and Date
      2010-03-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築IV2009

    • Author(s)
      鈴木陽子
    • Organizer
      日本物理学会
    • Place of Presentation
      熊本大学
    • Year and Date
      2009-09-27
    • Related Report
      2010 Final Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築IV2009

    • Author(s)
      鈴木陽子, Jeff K.Noel, Jose N.Onuchic
    • Organizer
      日本物理学会(秋季大会)
    • Place of Presentation
      熊本大学
    • Year and Date
      2009-09-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築III2009

    • Author(s)
      鈴木陽子
    • Organizer
      日本物理学会
    • Place of Presentation
      立教大学
    • Year and Date
      2009-03-28
    • Related Report
      2010 Final Research Report
  • [Presentation] トポロジカルな情報を考慮した蛋白質フォールディングの解析的モデルの構築III2009

    • Author(s)
      Yoko Suzuki, Jeff K. Noel, Jose N. Onuchic
    • Organizer
      日本物理学会(第64回年次大会)
    • Place of Presentation
      立教大学
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] An analytical Model for Protein folding2008

    • Author(s)
      鈴木陽子
    • Organizer
      International Symposium on Frontiers Computational Science 2008
    • Place of Presentation
      Nagoya University
    • Related Report
      2010 Final Research Report
  • [Presentation] An Analytical Model for Protein Folding

    • Author(s)
      Yoko Suzuki, JeffK. Noel, Jose N. Onuchic
    • Organizer
      International Symposium on Frontiers Computational Science 2008 (Nagoya University)
    • Place of Presentation
      名古屋大学(口頭発表)(ポスター発表)
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.hino.meisei-u.ac.jp/phys/youko/faculty/ysuzuki/index.html

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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