Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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Research Abstract |
In studying protein folding mechanism from analytical point of view, we introduce a model based on a Gaussian filament with an attractive force between a pair of residues forming a contact in the folded state and a repulsive force between any pairs of residues. By using this model, we estimate effects of the geometrical factors caused by a specific interaction based on a native structure and a non-specific interaction upon the folding mechanism.
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