| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
We demonstrated a novel technique to promote crystallization of hen egg-white lysozyme in heavy water. The technique was essentially based on aggregation of the protein molecules by photon pressure generated under irradiation of a cw 1064 nm laser beam to the protein solution. When photon pressure was kept being exerted for 1-2 hours on the sample solution, a small particle identified to the molecular aggregate of lysozyme was produced, as proved by in situ Raman microspectroscopy on the particle. Furthermore, we confirmed that aggregation of lysozyme by photon pressure led to crystallization of the protein.
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