STUDIES ON DEVELOPMENT OF NOVEL SPACERS OF BIS(2-ETHYNYL-3-THIENYL)ARENE TYPE AND THEIR INTERACTIONS

• Project/Area Number: 20550030
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Organic chemistry
• Research Institution: Tohoku University
• Principal Investigator: TOYOTA Kozo 東北大学, 大学院・理学研究科, 准教授 (50217569)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 分子建築 / 人工酵素 / スペーサー / 配位子 / 金属錯体 / 高分子 / 典型元素化合物 / 錯体触媒 / 有機典型元素化合物

Research Abstract

Proteins, composed from a main chain and various side chains, exhibit specific functionality. Mimicking the main chain and the side chains by artificial molecule is important area of research. We developed a novel molecular system including thienylarene main chain and various ethynyl side chains. This system is promising for development of new materials and catalysts.

Research Products

• [Journal Article] Preparation of 1, 4-Bis(2-ethynyl-3-thienyl)benzene Derivatives Linked by Oligo(ethyleneglycol)Chain (2011)
  • Author(s): K. Toyota, H. Katsuta, T. Iwamoto, and N. Morita
  • Journal Title: Heteroatom Chemistry Volume: Vol.22(印刷中)
  • Peer Reviewed
• [Journal Article] Preparation of 1,4-Bis(2-ethynyl-3-thienyl)benzene Derivatives Linked by Oligo(ethyleneglycol) Chain (2011)
  • Author(s): K.Toyota, H.Katsuta, T.Iwamoto, N.Morita
  • Journal Title: Heteroatom chemistry Volume: VoL.22(印刷中)
  • Peer Reviewed
• [Journal Article] An Efficient and Regioselective Iodination of Electron-rich Aromatic Compounds Using N-Chlorosuccinimide and Sodium Iodide (2010)
  • Author(s): T. Yamamoto, K. Toyota, N. Morita
  • Journal Title: Tetrahedron Letters Volume: Vol.51、No.10 Pages: 1364-1366
  • Peer Reviewed
• [Journal Article] Chemistry of Bis(2-ethynyl-3-thienyl)arene and Related Systems. Part 5 : Preparation of an Unsymmetrical 4, 4'-Di(3-thienyl)biphenyl Derivative Containing a 2-[2-(Diphenylphosphino)ethynyl]-3-thienyl Moiety (2010)
  • Author(s): K. Toyota, Y. Tsuji, and N. Morita
  • Journal Title: Phosphorus, Sulfur, Silicon and the Related Elements Volume: Vol.185、No.5-6 Pages: 983-991
  • Peer Reviewed
• [Journal Article] Preparation of an Unsymmetrical 4,4'-Di(3-thienyl)biphenyl Derivative Containing a 2-[2-(Diphenylphosphino)ethynyl]-3-thienyl Moiety (2010)
  • Author(s): K.Toyota, Y.Tsuji, N.Morita
  • Journal Title: Phosphorus, Sulfur, and Silicon and the Related Elements Volume: VOL.185 Pages: 983-991
  • Peer Reviewed
• [Journal Article] An Efficient and Regioselective Iodination of Electron-rich Aromatic Compounds Using N-Chlorosuccinimide and Sodium Iodide (2010)
  • Author(s): T.Yamamoto, K.Toyota, N.Morita
  • Journal Title: Tetrahedron Letters VOL.51 Pages: 1364-1366
  • Peer Reviewed
• [Journal Article] Preparation of 1, 4-Bis(3-ethynylthieno-[3, 2-b] thiophene-2-yl)benzene DerivativesAs Peptide-inspired Molecules (2009)
  • Author(s): K. Toyota, H. Katsuta, Y. Tsuji, T. Iwamoto, N. Morita
  • Journal Title: Heterocycles Volume: Vol.78、No.12 Pages: 3037-3051
  • Peer Reviewed
• [Journal Article] Preparation of 1, 4-Bis(2-ethynyl-3-thienyl)benzene Derivatives Containing Fluorine Atoms at the 2, 3-or 2, 5-Positions of the Benzene Ring (2009)
  • Author(s): K. Toyota, Y. Tsuji, N. Morita
  • Journal Title: Journal of Sulfur Chemistry Volume: Vol.30、No.3-4 Pages: 351-359
  • Peer Reviewed
• [Journal Article] Preparation of Unsymmetrical 1, 4-Bis[2-ethynyl-3-thienyl] benzene Derivative (2009)
  • Author(s): K. Toyota, Y. Tsuji, K. Okada, N. Morita
  • Journal Title: Heterocycles Volume: Vol.78、No.1 Pages: 127-138
  • NAID: 40016405914
  • Peer Reviewed
• [Journal Article] Preparation of 1, 4-Bis[2-{ 2-(1-methyl-1H-imidazol-5-yl)ethynyl}-3-thienyl] benzene and Related Compounds (2009)
  • Author(s): K. Toyota, K. Okada, H. Katsuta, Y. Tsuji, N. Morita
  • Journal Title: Heterocycles Volume: Vol.77、No.2 Pages: 1057-1064
  • NAID: 40016454344
  • Peer Reviewed
• [Journal Article] Preparations of Bis[2-(2-arylethynyl)-3-thienyl] arenes and Bis[2-{ 2-(trimethylsilyl)ethynyl}-3-thienyl] arenes (2009)
  • Author(s): K. Toyota, K. Okada, H. Katsuta, N. Morita
  • Journal Title: Tetrahedron Volume: Vol.65、No.1 Pages: 145-151
  • Peer Reviewed
• [Journal Article] Preparation of 1,4-Bis(2-ethynyl-3-thienyl)benzene Derivatives Containing Fluorine Atoms at the 2,3- or 2,5-Positions of the Benzene Ring (2009)
  • Author(s): K.Toyota, Y.Tsuji, N.Morita
  • Journal Title: Journal of Sulfur Chemistry VOL.30 Pages: 351-359
  • Peer Reviewed
• [Journal Article] Preparation of 1,4-Bis(3-ethynylthieno-[3,2-b]thiophene-2-yl)benzene Derivatives As Peptide-inspired Molecules (2009)
  • Author(s): K.Toyota, H.Katsuta, Y.Tsuji, T.Iwamoto, N.Morita
  • Journal Title: Heterocycles VOL.78 Pages: 3037-3051
  • NAID: 40016842012
  • Peer Reviewed
• [Journal Article] Preparations of Bis[2-(2-arylethynyl)-3-thienyl]arenes and Bis[2-{2-(trimethylsilyl) ethynyl}-3-thienyl] arenes (2009)
  • Author(s): K. Toyota, K. Okada, H. Katsuta, N. Morita
  • Journal Title: Tetrahedron 65 Pages: 145-151
  • Peer Reviewed
• [Journal Article] Preparation of 1,4-Bis[2-{2-(1-methyl-1H-imidazol-5-yl) ethynyl}-3-thienyl] benzene and Related Compounds (2009)
  • Author(s): K. Toyota, K. Okada, H. Katsuta, Y. Tsuji, N. Morita
  • Journal Title: Heterocycles 77 Pages: 1057-1064
  • NAID: 40016454344
  • Peer Reviewed
• [Journal Article] Preparation of Unsymmetrical 1,4-Bis[2-ethyny1-3-thienyl] benzene Derivative (2009)
  • Author(s): K. Toyota, Y. Tsuji, K. Okada, N. Morita
  • Journal Title: Heterocycles 78 Pages: 127-138
  • Peer Reviewed
• [Presentation] エチニルチエニルアレーン誘導体の合成、構造、及び分子建築への応用 (2010)
  • Author(s): 豊田耕三・辻恭朋・山本拓也・勝田弘・中村和宏・岩本武明・森田昇
  • Organizer: 第37回有機典型元素化学討論会
  • Place of Presentation: 室蘭市民会館(北海道)
  • Year and Date: 2010-11-25
• [Presentation] 側鎖を有するチオフェン系、チエノチオフェン系、ベンゾチオフェン系、およびチアゾール系分子建築材料の開発とその配列制御連結 (2010)
  • Author(s): 豊田耕三・山本拓也・辻恭朋・勝田弘・中村和宏・谷本大樹・岩本武明・森田昇
  • Organizer: 第40回複素環化学討論会
  • Place of Presentation: 仙台市民会館(宮城県)
  • Year and Date: 2010-10-14
• [Presentation] 生体模倣系を指向したエチニルチエニルアレーン連結系の拡張 (2010)
  • Author(s): 豊田耕三・山本拓也・辻恭朋・勝田弘・中村和宏・岩本武明・森田昇・黒田重靖
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学本部キャンパス(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] 生体模倣系を指向した、ビス(エチニル)チエニルアレーン連結系の構築と展開 (2009)
  • Author(s): 豊田耕三・勝田弘・辻恭朋・岩本武明・森田昇
  • Organizer: 第20回基礎有機化学討論会
  • Place of Presentation: 群馬大学工学部(群馬県)
  • Year and Date: 2009-09-28
• [Presentation] 生体模倣系を指向したビス(2-エチニル-3-チエニル)アレーン型スペーサーの開発と配列制御型連結の研究 (2008)
  • Author(s): 豊田耕三・辻恭朋・勝田弘・岡田和之・森田昇
  • Organizer: 第38回複素環化学討論会
  • Place of Presentation: 広島県民文化センターふくやま(広島県)
  • Year and Date: 2008-11-22
• [Presentation] 生体模倣系を指向したビス(2-エチニル-3-チエニル)アレーン型スペーサーの開発と配列制御連結の研究 (2008)
  • Author(s): 豊田耕三・辻恭朋・勝田弘・岡田和之・森田昇
  • Organizer: 第38回複素環化学討論会
  • Place of Presentation: 福山
  • Year and Date: 2008-11-22
• [Remarks]
  • URL: http://www.chem.tohoku.ac.jp/lab/organic/synthetic_and_structural_organic_chemistry_j.html
• [Remarks]
  • URL: http://www.chem.tohoku.ac.jp/lab/organic/synthetic_and_structural_organic_chemistry_j.html
• [Remarks]
  • URL: http://www.chem.tohoku.ac.jp/lab/organic/synthetic_and_structural_organic_chemistry_j.html