Development of novel sulfur-atom donating agents intended to thiiranate alkenes
Project/Area Number |
20550032
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Organic chemistry
|
Research Institution | Saitama University |
Principal Investigator |
YOSHIAKI Sugihara Saitama University, 理工学研究科, 准教授 (00272279)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 硫黄原子導入 / 三員環化合物 / アルケン / チイラン / チイラン化 / 電子吸引性基 / 脱離基 / 塩化スルファニル / 塩化スルフェニル / 溶媒効果 / 固相反応 / シリカゲル / 水素結合 / ジチオビストリアゾール / 1,2-ベンゾジチオール-3-オン1,1-ジオキシド / トリフェニルメタンスルフェニル / サッカリン |
Research Abstract |
Sulfur-atom donating reagents taking advantage of both the electron withdrawing character and the leaving group ability of the substituents bonding directly with the sulfur atom were easily synthesized from inorganic or organic sulfur compounds. As a result of investigating their sulfuration ability, some reagents were found to thiiranate alkenes with retention of configuration. The reagent synthesized from artificial sweetener saccharin was able to sulfurate benzothiophene, one of the electron-rich heteroaromatic compo unds, under mild reaction conditions.
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Report
(4 results)
Research Products
(45 results)