Development of novel chiral bronsted acid catalyst based on intramolecular hydrogen bonding
| Project/Area Number |
20550045
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Organic chemistry
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
TAKAGI Ryukichi Hiroshima University, 大学院・理学研究科, 助教 (90304394)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 合成有機化学 / 有機分子触媒 / 不斉反応 / 水素結合 / Diels-Alder反応 / 不斉合成 / ブレンステッド酸 |
|---|
| Research Abstract |
A novel chiral bronsted acid catalyst based on intramolecular hydrogen bonding have been developed. The novel chiral bronsted acid slightly accelerated the Diels-Alder reaction of cross-conjugated dienone and cyclopentadiene than the original one. ONIOM calculations suggested that the chiral bronsted acid interact with the dienone by double hydrogen bond in the Diels-Alder reaction.
|
Report
(4 results)
Research Products
(20 results)
