Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Research Abstract |
Metal-catalyzed coupling reaction between aryl and fluorofunctional group was studied. Firstly, we investigated the electronic effect of supporting ligand on reductive elimination of biaryl. As a result, we found that the strong electron-poor diphosphine ligand accelerated reductive elimination of biaryl. Secondly, we tried the reductive elimination of aryl and fluorofunctional group from palladium catalyst bearing strong electron-poor ligand. However, the complex was decomposed before reductive elimination at high reaction temperature.
|