Preparation of hydrophilic reactive biocompatible surface of amphiphilic block copolymer
| Project/Area Number |
20550108
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Polymer chemistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
ISHIZONE Takashi Tokyo Institute of Technology, 大学院・理工学研究科, 准教授 (60212883)
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| Co-Investigator(Renkei-kenkyūsha) |
YOKOYAMA Hideaki 東京大学, 新領域創成科学研究科, 准教授 (80358316)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 高分子合成 / 両親媒性ブロック共重合体 / 水溶性ポリマー / 感温性ポリマー / 側鎖末端基 / メタクリル酸トリ(エチレングリコール)ビニルエーテル / リビングアニオン重合 / ポリ(メタクリル酸トリエチレングリコール / ポリ(メタクリル酸トリエチレングリコール) |
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| Research Abstract |
A series of new amphiphilic block copolymers composed of water-soluble polymethacrylate and hydrophobic polystyrene was synthesized by the living anionic polymerization. Novel polymer surface showing hydrophilicity, reactivity, and biocompatibility was obtained by casting the block copolymer solution. The hydrophobic alkyl terminal groups in the side chains of polymethacrylate played important roles to achieve the surface segregation of water-soluble polymethacrylate segments.
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Report
(4 results)
Research Products
(50 results)
