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Optimal design of the transmission-way of mechanical stress throughthe interface between a joint prosthesis and bone tissue together with the criterion formulation for the assessment of the fixation method

Research Project

Project/Area Number 20560086
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionKitasato University

Principal Investigator

MABUCHI Kiyoshi  Kitasato University, 医療衛生学部, 教授 (70118842)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords生体工学 / 人工関節 / セメントレス固定 / 定常荷重 / 力学応答 / 超弾性 / 骨肥厚 / 固定法 / 残留応力 / プレスフイット / 大腿部痛 / 有限要素法 / von Mises相当応力 / 近位プレート
Research Abstract

Failure criteria of ultra-high molecular weight polyethylene (UHMWPE) should be clarified for the strength design of joint prostheses. In the present study, we performed compression tests of UHMWPE plates together with finite element (FE) analysis under conditions similar to those within a total knee prosthesis and discuss the failure criteria.
Flat plates made of conventional or cross linked UHMWPE were molded as test pieces. Those thicknesses were ranging from 2 mm to 8 mm. The compression test using a loading machine was performed in a bath filled with saline solution at 37 degrees centigrade. A metallic sphere 50 mm in diameter was used for the indenter. The load was applied to 6 kN under a crosshead speed of 2 mm per minute. Flow pressure was calculated after the test as a ratio of the impressio area and the maximum load. Deformation of the plate was estimated by displacement at the edge. Additionally, the FE analysis was performed on a virtual model using the same conditions as in … More the experiments.
The values of the flow pressure were measured as a mean of 32.8 MPa, SD 2.3 MPa for conventional UHMWPE, and as a mean of 37.3 MPa, SD 0.9 MPa for cross-linked UHMWPE. The displacement of the UHMWPE plate increased with decreasing thickness of the plate. The displacement estimated by FE analysis was similar to that of the
experimental findings. Furthermore, shear strain in the UHMWPE plate of FE model increased with the displacement. It was concluded that the failure criteria of joint prostheses must be presented by not only the stress but also the strain in a UHMWPE insert.
Stress in bone tissue must be remained after the press-fit-fixation of a implant. The residual stress must bring on the biological response around the implant. The effect has not been sufficiently discussed, yet, because the residual stress is stationary and unlike the physiological mechanical conditions.
In the present study, we developed a method to configure stationary stress field in a rat femur using a pin with the hyper elasticity. As the results, it was observed that bone hypertrophy emerged at the fringe of the femur under six weeks stationary load from the pin inside bone marrow. Less

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (40 results)

All 2011 2010 2009 2008 Other

All Journal Article (20 results) (of which Peer Reviewed: 19 results) Presentation (16 results) Book (2 results) Remarks (2 results)

  • [Journal Article] 人工膝関節ポリエチレンインサートの圧縮強度基準2010

    • Author(s)
      馬渕清資, 酒井利奈, 占部憲
    • Journal Title

      臨床バイオメカニクス 31

      Pages: 207-212

    • NAID

      10027911570

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 転子間プレート固定を施した人工股関節ステムの接触圧力の測定と有限要素解析2010

    • Author(s)
      尾畑幸代, 酒井利奈, 馬渕清資
    • Journal Title

      臨床バイオメカニクス 31

      Pages: 277-282

    • NAID

      10027911679

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 人工股関節ステムのセメントレス固定における術中骨折の発生条件2010

    • Author(s)
      酒井利奈, 高橋亮子, 馬渕清資, 高平尚伸, 糸満盛憲
    • Journal Title

      臨床バイオメカニクス 31

      Pages: 271-276

    • NAID

      10027911669

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 人工膝関節ポリエチレンインサートの圧縮強度基準2010

    • Author(s)
      馬渕清資, 酒井利奈, 占部憲
    • Journal Title

      臨床バイオメカニクス

      Volume: 31 Pages: 207-212

    • NAID

      10027911570

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 人工股関節ステムのセメントレス固定における術中骨折の発生条件2010

    • Author(s)
      酒井利奈, 高橋亮子, 馬渕清資, 高平尚伸, 糸満盛憲
    • Journal Title

      臨床バイオメカニクス

      Volume: 31 Pages: 271-276

    • NAID

      10027911669

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 転子間プレート固定を施した入工股関節ステムの接触圧力の測定と有限要素解析2010

    • Author(s)
      尾畑幸代, 酒井利奈, 馬渕清資
    • Journal Title

      臨床バイオメカニクス

      Volume: 31 Pages: 277-282

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マイクロモーションとvon Mises応力によって評価したAI-Hip cementless stem有限要素モデルの初期固定性2009

    • Author(s)
      酒井利奈, 佐藤祐輔, 糸満盛憲, 馬渕清資
    • Journal Title

      バイオメカニズム学会誌 33(1)

      Pages: 71-77

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 軸旋型人工股関節ステムのプレート部における微可動の有用性2009

    • Author(s)
      酒井利奈, 小川直, 尾畑幸代, 糸満盛憲, 前澤伯彦, 馬渕清資
    • Journal Title

      日本生体医工学会誌 47(5)

      Pages: 417-422

    • NAID

      10031199700

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素解析による人工股関節ステムのフランジモデルとカラーモデルの応力分布の比較2009

    • Author(s)
      酒井利奈, 小川直樹, 糸満盛憲, 尾畑幸代, 菊池康博, 馬渕清資
    • Journal Title

      臨床バイオメカニクス 30

      Pages: 287-292

    • NAID

      10026981834

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Finite element analysis of the effect of proximal interlocking on primary fixation of the Intra-Medullary Cruciate stem.2009

    • Author(s)
      Sakai R, Sato K, Itoman M, Mabuchi K
    • Journal Title

      J Orthopaedic Science 14(1)

      Pages: 85-95

    • NAID

      10025353637

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hyperlipidemia and hyperinsulinemia in the spontaneous osteoarthritis mouse model, STR/Ort.2009

    • Author(s)
      Uchida K, Urabe K, Naruse K, Ujihira M, Ogawa Z, Mabuchi K, Itoman M
    • Journal Title

      Experimental Animals 58

      Pages: 181-187

    • NAID

      10024838420

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素解析による人工股関節ステムのフランジモデルとカラーモデルの応力分布の比較.2009

    • Author(s)
      酒井利奈, 小川直樹, 糸満盛憲, 尾畑幸代, 菊池康博, 馬渕清資
    • Journal Title

      臨床バイオメカニクス 30

      Pages: 287-292

    • NAID

      10026981834

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 人工関節に使用されている超高分子量ポリエチレンの圧縮強度.2009

    • Author(s)
      川嵜康雄, 酒井利奈, 馬渕清資
    • Journal Title

      日本人工関節学会誌 39

      Pages: 298-299

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Morphologic differences of the distal femur between Caucasian and Japanese women.2008

    • Author(s)
      Urabe K, Mahoney OM, Mabuchi K, Itoman M
    • Journal Title

      J Orthopaedic Surgery 16(3)

      Pages: 312-315

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素法によって評価したAi HipCementless Stemの初期固定性2008

    • Author(s)
      酒井利奈, 佐藤祐輔, 糸満盛憲, 馬渕清資
    • Journal Title

      日本臨床バイオメカニクス学会誌 29

      Pages: 337-341

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素法によって評価した人工股関節ステム初期固定性に対する近位横止めピンの効果2008

    • Author(s)
      酒井利奈, 佐藤祐輔, 糸満盛憲, 馬渕清資
    • Journal Title

      バイオメカニクス学会誌 32(2)

      Pages: 98-105

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rotational stability based on displacements obtained by simulation and measurement when torsion loading is applied to hip stems.2008

    • Author(s)
      Sakai R, Iwama A, Itoman M, Mabuchi K
    • Journal Title

      J Orthopaedic Science 13(3)

      Pages: 248-254

    • NAID

      10024139640

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rotational stability based on displacements obtained by simulation and measurement when torsion loading is applied to hip stems2008

    • Author(s)
      Sakai R, Iwama A, Itoman M, Mabuchi K
    • Journal Title

      Journal of Orthopaedic Science 13

      Pages: 248-254

    • NAID

      10024139640

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素法によって評価した人工股関節ステム初期固定性に対する近位横止めピンの効果2008

    • Author(s)
      酒井利奈, 佐藤祐輔, 糸満盛憲, 馬渕清資
    • Journal Title

      バイオメカニクス学会誌 32

      Pages: 98-105

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素法によって評価したAi Hip Cementless stemの初期固定性2008

    • Author(s)
      酒井利奈, 佐藤祐輔, 糸満盛憲, 馬渕清資
    • Journal Title

      日本臨床バイオメカニクス学会誌 29

      Pages: 337-341

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 人工股関節の流体潤滑性能に及ぼす加工精度の影響2011

    • Author(s)
      馬渕清資, 平木祐哉, 酒井利奈, 田中健誠, 中川博央
    • Organizer
      第41回日本人工関節学会
    • Place of Presentation
      東京
    • Year and Date
      2011-02-26
    • Related Report
      2010 Final Research Report
  • [Presentation] せん断ひずみを基準とした人工膝関節ポリエチレンインサートの塑性設計2011

    • Author(s)
      田中健誠, 酒井利奈, 占部憲, 川崎康雄, 馬渕清資
    • Organizer
      第41回日本人工関節学会
    • Place of Presentation
      東京
    • Year and Date
      2011-02-26
    • Related Report
      2010 Final Research Report
  • [Presentation] 人工股関節の流体潤滑性能に及ぼす加工精度の影響2011

    • Author(s)
      馬渕清資
    • Organizer
      第41回日本人工関節学会
    • Place of Presentation
      グランドプリンスホテル赤坂(東京)
    • Year and Date
      2011-02-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 硬い材料同士の摩擦面を有する人工股関節の加工精度と流体潤滑性能2011

    • Author(s)
      平木祐哉, 中川博央, 田中健誠, 酒井利奈, 西浦淳, 馬渕清資
    • Organizer
      第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 人工股関節ステムのセメントレス固定における打ち込み力の推定2011

    • Author(s)
      森田とわ, 菊地亜紀, 高平尚伸, 酒井利奈, 馬渕清資
    • Organizer
      第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 全人工股関節置換術後のDuetto SI stem周囲における骨密度と応力の測定2011

    • Author(s)
      田中健誠, 酒井利奈, 山本豪明, 倉鍵侑一郎, 馬渕清資
    • Organizer
      第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] インプラント界面に残留する定常荷重の骨組織への影響2010

    • Author(s)
      馬渕清資, 薬師神宏, 酒井利奈, 内田健太郎, 成瀬康治
    • Organizer
      日本臨床バイオメカニクス学会
    • Place of Presentation
      京都
    • Year and Date
      2010-11-02
    • Related Report
      2010 Final Research Report
  • [Presentation] インプラント界面に残留する定常荷重の骨組織への影響2010

    • Author(s)
      馬渕清資
    • Organizer
      日本臨床バイオメカニクス学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2010-11-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] 金属同士を摩擦面とした人工股関節の潤滑特性に及ぼす形状パラメータの影響2010

    • Author(s)
      馬渕清資, 平木祐哉, 田中健誠, 酒井利奈, 西浦淳, 中川博央
    • Organizer
      日本機械学会2010年度年次大会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-09-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 金属同士を摩擦面とした人工股関節の潤滑特性に及ぼす形状パラメータの影響2010

    • Author(s)
      馬渕清資
    • Organizer
      日本機械学会 2010年度年次大会
    • Place of Presentation
      名古屋工業大学(名古屋)
    • Year and Date
      2010-09-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 工学者の立場からみた人工股関節形成術2010

    • Author(s)
      馬渕清資
    • Organizer
      平成22年度関東地区整形外科勤務医会総会
    • Place of Presentation
      大日本製薬会議室(東京)
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 有限要素法によって評価したステム近位部のフランジの有用性2009

    • Author(s)
      酒井利奈, 小川直, 尾畑幸代, 糸満盛憲, 馬渕清資
    • Organizer
      第39回日本人工関節学会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Failure criterion of ultra-high molecular weight polyethylene at high-stress contact in a total knee prosthesis.2009

    • Author(s)
      Mabuchi K, Kawasaki Y, Sakai R
    • Organizer
      World Tribology Congress 2009
    • Place of Presentation
      Kyoto
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 医工の接点としての人工関節2008

    • Author(s)
      馬渕清資
    • Organizer
      第57回東海関節外科研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-11-22
    • Related Report
      2010 Final Research Report
  • [Presentation] Primary fixation of finite element model of IMC stem evaluated by micro motion.2008

    • Author(s)
      Ogawa N, Sakai R, Sato K, Obata S, Itoman M, Mabuchi K
    • Organizer
      The 21st Ann. Congrs. Int. Soc. for Technology in Arthroplasty
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Primary fixation of finite element model of IMC stem evaluated by micro motion.2008

    • Author(s)
      Ogawa N, Sakai R, Sato K, Obata S, Itoman M, Mabuchi K
    • Organizer
      The 21st Ann Cong International Society of Technology A
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-01
    • Related Report
      2010 Final Research Report
  • [Book] 第3部バイオメカニクス・生体材料研究§17人工関節のバイオメカニクス研究の歩みと展望.編著大西啓靖,我が国の人工関節の研究開発,臨床応用の歩みと21 世紀の展望 大阪2008

    • Author(s)
      馬渕清資(分担), 他29名
    • Publisher
      大西啓靖記念人工関節研究センター発行
    • Related Report
      2010 Final Research Report
  • [Book] 我が国の人工関節の研究開発, 臨床応用の歩みと21世紀の展望第3部バイオメカニクス・生体材料研究§17人工関節のバイオメカニクス研究の歩みと展望.2008

    • Author(s)
      馬渕清資(分担), 他29名
    • Total Pages
      417
    • Publisher
      大西啓靖記念人工関節研究センター
    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.ahs.kitasato-u.ac.jp/~seitai/Lab1015.htm

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.ahs.kitasato-u.ac.jp/~seitai/Lab1015.htm

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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