Development of three-dimensional polylactic acid-piezoelectric material scaffold
| Project/Area Number |
20560091
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Doshisha University |
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Principal Investigator |
KATAYAMA Tsutao Doshisha University, 生命医科学部, 教授 (70161065)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMACHI Eiji 同志社大学, 生命医科学部, 教授 (60099893)
TANAKA Kazuto 同志社大学, 生命医科学部, 准教授 (50303855)
MORITA Yusuke 同志社大学, 生命医科学部, 准教授 (80368141)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 生体材料 / 圧電材料 / 足場材料 / 骨髄細胞 / 骨分化 / 薄膜創裂 / チタン酸バリウム / 骨再生 / 骨代替材料 / スキャホールド / 薄膜創製 |
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| Research Abstract |
A cultivation system was designed to evaluate piezoelectric effects of the BaTiO_3 (BTO) ceramics on bone marrow cells, and rat bone marrow cells seeded on surfaces of the BTO ceramics were cultured in culture medium. ALP activity on the charged BTO surface was slightly higher than that on the non-charged BTO surface. The amount of calcium on the charged BTO surface was also higher than that on the non-charged BTO surface. These results showed that the electric charged BTO surface enhanced osteogenic differentiation.
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Report
(4 results)
Research Products
(16 results)
