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Development of three-dimensional polylactic acid-piezoelectric material scaffold

Research Project

Project/Area Number 20560091
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionDoshisha University

Principal Investigator

KATAYAMA Tsutao  Doshisha University, 生命医科学部, 教授 (70161065)

Co-Investigator(Kenkyū-buntansha) NAKAMACHI Eiji  同志社大学, 生命医科学部, 教授 (60099893)
TANAKA Kazuto  同志社大学, 生命医科学部, 准教授 (50303855)
MORITA Yusuke  同志社大学, 生命医科学部, 准教授 (80368141)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords生体材料 / 圧電材料 / 足場材料 / 骨髄細胞 / 骨分化 / 薄膜創裂 / チタン酸バリウム / 骨再生 / 骨代替材料 / スキャホールド / 薄膜創製
Research Abstract

A cultivation system was designed to evaluate piezoelectric effects of the BaTiO_3 (BTO) ceramics on bone marrow cells, and rat bone marrow cells seeded on surfaces of the BTO ceramics were cultured in culture medium. ALP activity on the charged BTO surface was slightly higher than that on the non-charged BTO surface. The amount of calcium on the charged BTO surface was also higher than that on the non-charged BTO surface. These results showed that the electric charged BTO surface enhanced osteogenic differentiation.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (16 results)

All 2011 2009

All Presentation (16 results)

  • [Presentation] ラット骨髄細胞の骨分化に及ぼす表面電荷の影響2011

    • Author(s)
      古谷桂樹,森田有亮,田中和人,片山傳生,仲町英治
    • Organizer
      日本機械学会関西支部第86期定時総会講演会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2011-03-19
    • Related Report
      2010 Final Research Report
  • [Presentation] ラット骨髄細胞の骨分化に及ぼす表面電荷の影響2011

    • Author(s)
      古谷桂樹, 森田有亮, 田中和人, 片山傳生, 仲町英治
    • Organizer
      日本機械学会関西支部 第86期定時総会・講演会
    • Place of Presentation
      京都府京都市, 京都工芸繊維大学松ヶ崎キャンパス第4室
    • Year and Date
      2011-03-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Acceleration of osteogenesis by using barium titanate piezoelectric ceramic as an implant material2011

    • Author(s)
      K. Furuya, Y.Morita, K.Tanaka, T.Katayama, E.Nakamachi
    • Organizer
      International Society for Photo-optical Instrumentation Engineers(SPIE) Smart Structures/NDE
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-08
    • Related Report
      2010 Final Research Report
  • [Presentation] Acceleration of osteogenesis by using barium titanate piezoelectric ceramic as an implant material2011

    • Author(s)
      Keijyu Furuya, Yusuke MORITA, Kazuto TANAKA, Tsutao KATAYAMA, Eiji NAKAMACHI
    • Organizer
      International Society for Photo-optical Instrumentation Engineers(SPIE)2011 Smart Structures/NDE
    • Place of Presentation
      San Diego California, USA Town and Country Resort and Convention Center
    • Year and Date
      2011-03-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 骨置換材の表面電荷によるラット骨髄細胞の骨分化促進に関する研究2011

    • Author(s)
      古谷桂樹,森田有亮,田中和人,片山傳生,仲町英治
    • Organizer
      第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本県熊本市
    • Year and Date
      2011-01-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨置換材の表面電荷によるラット骨髄細胞の骨分化促進に関する研究2011

    • Author(s)
      古谷桂樹, 森田有亮, 田中和人, 片山傳生, 仲町英治
    • Organizer
      日本機械学会第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本県熊本市, 熊本大学工学部第2号館C室
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of BaTiO_3 piezoelectric thin film coating on bone marrow cell2009

    • Author(s)
      Y.Tateyama, Y.Morita, K.Tanaka, T.Katayama, E.Nakamachi
    • Organizer
      Asian Pacific Conference for Materials and Mechanics
    • Place of Presentation
      Yokohama
    • Year and Date
      2009-11-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of BaTiO3 Piezoelectric Thin Film Coating on Bone Marrow Cell2009

    • Author(s)
      Y.Takayama, Y.Morita, K.Tanaka, T.Katayama, E.Nakamachi
    • Organizer
      Asian Pacific Conference for Material and Mechanics 2009
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2009-11-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] BaTiO_3圧電薄膜が骨髄細胞に及ぼす影響2009

    • Author(s)
      立山優貴,森田有亮,古谷桂樹,田中和人,片山傳生,仲町英治
    • Organizer
      日本機械学会2009年度年次大会
    • Place of Presentation
      岩手県盛岡市
    • Year and Date
      2009-09-14
    • Related Report
      2010 Final Research Report
  • [Presentation] BaTiO3圧電薄膜が骨髄細胞に及ぼす影響2009

    • Author(s)
      立山優貴, 森田有亮, 古谷佳樹, 田中和人, 片山傳生, 仲町英治
    • Organizer
      日本機械学会2009年度年次大会
    • Place of Presentation
      岩手大学(盛岡市)
    • Year and Date
      2009-09-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effects of BaTiO_3 piezoelectric thin film coating on activity of rat bone marrow cell2009

    • Author(s)
      Y.Tateyama, Y.Morita, K.Tanaka, T.Katayama, E.Nakamachi
    • Organizer
      Medical Physics and Biomedical Engineering World Congress
    • Place of Presentation
      Munich, German
    • Year and Date
      2009-09-08
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of BaTiO3 Piezoelectric Thin Film Coating on Activity of Rat Bone Marrow Cell2009

    • Author(s)
      Y.Takayama, Y.Morita, K.Tanaka, T.Katayama, E.Nakamachi
    • Organizer
      Medical Physics and Biomedical Engineering World Congress 2009
    • Place of Presentation
      Munich/German
    • Year and Date
      2009-09-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] 圧電材料チタン酸バリウムが骨髄細胞の活性に与える影響2009

    • Author(s)
      立山優貴,森田有亮,田中和人,片山傳生,仲町英治
    • Organizer
      2009年度砥粒加工学会
    • Place of Presentation
      埼玉県行田市
    • Year and Date
      2009-09-02
    • Related Report
      2010 Final Research Report
  • [Presentation] BaTiO_3圧電薄膜コーティングによる骨再生促進の評価2009

    • Author(s)
      立山優貴, 森田有亮, 古谷桂樹, 田中和人, 片山傅生, 仲町英治
    • Organizer
      日本機械学会関西支部第84 期定時総会講演会
    • Place of Presentation
      近畿大学
    • Year and Date
      2009-03-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 骨誘導促進のためのBaTiO_3圧電薄膜の生体適合性評価2009

    • Author(s)
      古谷桂樹,立山優貴,森田有亮,田中和人,片山傳生,仲町英治
    • Organizer
      日本機械学会関西学生会学生員卒業研究発表会
    • Place of Presentation
      大阪府東大阪市小若江3-4-1
    • Year and Date
      2009-03-15
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨誘導促進のためのBaTiO_3圧電薄膜の生体適合性評価2009

    • Author(s)
      古谷桂樹, 立山優貴, 森田有亮, 田中和人, 片山傅生, 仲町英治
    • Organizer
      日本機械学会 関西学生会平成20年度学生員卒業研究発表講演会
    • Place of Presentation
      近畿大学
    • Year and Date
      2009-03-15
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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