| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Research Abstract |
In this study, we have developed an automatic hypnosis and analgesia control system during day-case surgery using a model predictive controller. First, we proposed an index combining pulse rate and the Entropy Difference obtained by spectral analysis of electroencephalogram as an analgesia index available during day-case surgery, and confirmed that the index can be used for adjusting infusion rate of remifentanil. Then, we constructed a model of hypnosis and analgesia responses to propofol and remifentanil considering interaction of the drugs and dead times. Furthermore, we developed an identification function of individual parameters during anesthesia induction. The simulation results show that the developed system has a good performance.
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