Study on Analgesia Control in Balanced Anesthesia
| Project/Area Number |
20560412
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Control engineering
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| Research Institution | Kyoto University |
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Principal Investigator |
FURUTANI Eiko Kyoto University, 工学研究科, 准教授 (40219118)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 鎮痛度制御 / remifentanil / 鎮痛度指標 / propofol / 鎮静度制御 / モデル予測制御 / バランス麻酔 / パラメータ同定 / 鎮痛度 / 相互作用 / 薬力学モデル |
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| Research Abstract |
In this study, we have developed an automatic hypnosis and analgesia control system during day-case surgery using a model predictive controller. First, we proposed an index combining pulse rate and the Entropy Difference obtained by spectral analysis of electroencephalogram as an analgesia index available during day-case surgery, and confirmed that the index can be used for adjusting infusion rate of remifentanil. Then, we constructed a model of hypnosis and analgesia responses to propofol and remifentanil considering interaction of the drugs and dead times. Furthermore, we developed an identification function of individual parameters during anesthesia induction. The simulation results show that the developed system has a good performance.
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Report
(4 results)
Research Products
(8 results)
