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Study on the Formation Mechanism of Bio-Nanostructures by a Micro-Fluidic Force

Research Project

Project/Area Number 20560701
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Properties in chemical engineering process/Transfer operation/Unit operation
Research InstitutionKobe University

Principal Investigator

SUZUKI Hiroshi  Kobe University, 大学院・工学研究科, 教授 (90206524)

Co-Investigator(Kenkyū-buntansha) KOMODA Yoshiyuki  神戸大学, 大学院・工学研究科, 准教授 (00397796)
KATSUDA Tomohisa  神戸大学, 大学院・工学研究科, 助教 (50335460)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords化学工学 / 生物・生体工学 / マイクロ・ナノデバイス / 自己組織化 / ナノ材料
Research Abstract

In order to investigate the formation mechanism of liposomes in a micro-channel, an experimental study has been performed. The Lagrangian observations and velocity field measurements by a micro-PTV were carried out by use of a movable stage. From the results, it was found that the lipid film pre-coated on the wall were taken into the liquid/air interface and the rod-like liposomes were formed between the interface and the wall and that the rod-like liposomes becomes spherical liposomes in a flow. It was also found that the rod-like liposomes serially induced from the interface by the strong reverse flow existing near the interface

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (9 results)

All 2010 2009 2008

All Presentation (9 results)

  • [Presentation] Micro-Fluidic Behavior on Liposome Production in a Micro-Channel2010

    • Author(s)
      Atsushi FUJIWARA, Hiroshi SUZUKI, Tomohisa KATSUDA, Yoshiyuki KOMODA
    • Organizer
      13^<th> Asian Pacific Confederation of Chemical Engineering Congress
    • Place of Presentation
      Taipei(Taiwan)
    • Year and Date
      2010-10-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロ流路内におけるリポソーム生成機構2010

    • Author(s)
      藤原淳, 濱村準矢, 鈴木洋, 勝田知尚, 菰田悦之, 薄井洋基
    • Organizer
      化学工学会第74年会
    • Place of Presentation
      D114,横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロ流路内におけるリポソーム生成時のマイクロ流体挙動に関する研究2010

    • Author(s)
      藤原淳, 鈴木洋, 菰田悦之, 勝田知尚
    • Organizer
      化学工学会第42回秋季大会
    • Place of Presentation
      #N106,京都
    • Related Report
      2010 Final Research Report
  • [Presentation] Micro-Fluidic Behavior on Liposome Production in a Micro-Channel2010

    • Author(s)
      藤原淳, 鈴木洋, 勝田知尚, 菰田悦之
    • Organizer
      13^<th> Asia Pacific Confederation of Chemical RNgineering Congress
    • Place of Presentation
      #10338, Taipei
    • Related Report
      2010 Final Research Report
  • [Presentation] Visualization of Liposome Production in a Micro-Tube2009

    • Author(s)
      Atsushi FUJIWARA, Hiroshi SUZUKI, Tomohisa KATSUDA, Yoshiyuki KOMODA, Shigeo KATO, Hiromoto USUI
    • Organizer
      Asia Pacific Biochemical Engineering Conference '09
    • Place of Presentation
      Kobe International Conference Center, Kobe, Japan
    • Year and Date
      2009-11-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロ流路内におけるリポソーム生成機構2009

    • Author(s)
      藤原淳, 濱村隼矢, 鈴木洋, 勝田知尚, 菰田悦之, 薄井洋基
    • Organizer
      化学工学会74年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Visualization of Liposome Production in a Micro-Tube2009

    • Author(s)
      Atsushi FUJIWARA, Hiroshi SUZUKI, Tomohisa KATSUDA, Yoshiyuki KOMODA, Shigeo KATO, Hiromoto USUI
    • Organizer
      Proceedings of Asia Pacific Biochemical Engineering Conference'09
    • Place of Presentation
      #BP-03, Kobe
    • Related Report
      2010 Final Research Report
  • [Presentation] Liposomc Formation Characteristics with a Micro-Reactor2008

    • Author(s)
      J. Hamamura, H. Suzuki, T. Katsuda, Y. Komoda, S. Kato, H. Usui
    • Organizer
      11^<th> Liposome Research Days Conference
    • Place of Presentation
      横浜
    • Year and Date
      2008-07-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] Liposome Formation Characteristics with a Micro-Reactor2008

    • Author(s)
      Jun-ya HAMAMURA, Hiroshi SUZUKI, Tomohisa KATSUDA, Yoshiyuki KOMODA, Shigeo KATOH, Hiromoto USUI
    • Organizer
      Proceedings of 11^<th> Liposome Research Days Conference
    • Place of Presentation
      #P95Y, Yokohama
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2017-10-13  

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