Transcriptome analysis to understand the mechanisms of the restarting of bacterial growth after the stationary phase.
| Project/Area Number |
20570006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Osaka Medical College |
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Principal Investigator |
MAKI Yasushi Osaka Medical College, 医学部, 講師 (60401733)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 細菌 / マイクロアレイ / 増殖 / 大腸菌 |
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| Research Abstract |
To reveal the mechanisms to restart the proliferation of the bacterial cells from the growth suspending, I have performed the microarray analysis of the cells of various states through the cell cycle, using Escherichia coli cells as the model bacteria in this study. The results showed that many genes are transcribed in the early period of the restarting growth after the inoculation of the cells of stationary phase into the fresh medium, and that the physiological states, as well as the profiles of the gene expressions, of the cells of nonproliferation periods are varying according to the nutrient environments.
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Report
(4 results)
Research Products
(22 results)
