Study on the relationship between amino acid substitutions and natural selection taking into account the three dimensional structure of proteins

• Project/Area Number: 20570008
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Genetics/Genome dynamics
• Research Institution: National Institute of Genetics
• Principal Investigator: SUZUKI Yoshiyuki National Institute of Genetics, 大学院・システム自然科学研究科, 教授 (70353430)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: 進化 / 蛋白質 / 立体構造 / アミノ酸置換 / 自然選択

Research Abstract

A phylogenetic window analysis method was developed for detecting chronological changes in natural selection. CpG hypermutability was also taken into account for detecting natural selection. It was clarified that converting the alignment of amino acid sequences into that of codon sequences causes biased inference of natural selection. Influenza virus appeared to escape from host immune responses continuously in the tropical region. A method for detecting reassortment from a large number of genomic sequences was also developed.

Research Products

• [Journal Article] Overestimation of nonsynonymous/synonymous rate ratio by reverse-translation of aligned amino acid sequences. (2011)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Genes & Genetic Systems 86 Pages: 73-78
  • NAID: 10029516542
  • Peer Reviewed
• [Journal Article] Evolutionary history of dog rabies in Brazil. (2011)
  • Author(s): Yuki Kobayashi, Yoshiyuki Suzuki, Takuya Itou, Fumio H. Ito, Takeo Sakai, Takashi Gojobori
  • Journal Title: Journal of General Virology 92 Pages: 85-90
  • Peer Reviewed
• [Journal Article] Statistical methods for detecting natural selection from genomic data. (2010)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Genes & Genetic Systems 85 Pages: 359-376
  • NAID: 10029515818
  • Peer Reviewed
• [Journal Article] Genetic evidence supports linguistic affinity of Mlabri-a hunter-gatherer group in Thailand. (2010)
  • Author(s): Shuhua Xu, Daoroong Kangwanpong, Mark Seielstad, Metawee Srikummool, Jatupol Kampuansai, Li Jin, The HUGO Pan-Asian SNP Consortium
  • Journal Title: BMC Genetics 11 Pages: 18-18
  • Peer Reviewed
• [Journal Article] Genomic events contributing to high prevalence of amantadine-resistant influenza A/H3N2. (2010)
  • Author(s): Hassan Zaraket, Reiko Saito, Yasushi Suzuki, Yoshiyuki Suzuki, Isolde Caperig-Dapat, Clyde Dapat, Iman I. Shabana, Tatiana Baranovich, Hiroshi Suzuki
  • Journal Title: Antiviral Therapy 15 Pages: 307-319
  • Peer Reviewed
• [Journal Article] The neutral theory of molecular evolution in the genomic era. (2010)
  • Author(s): Masatoshi Nei, Yoshiyuki Suzuki, Masafumi Nozawa
  • Journal Title: Annual Review of Genomics and Human Genetics 11 Pages: 265-289
  • Peer Reviewed
• [Journal Article] Is positive selection responsible for the evolution of a duplicate UV-sensitive opsin gene in Heliconius butterflies (2010)
  • Author(s): Masafumi Nozawa, Yoshiyuki Suzuki, Masatoshi Nei
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America 107
  • Peer Reviewed
• [Journal Article] Endogenous non-retroviral RNA virus elements in mammalian genomes. (2010)
  • Author(s): Masayuki Horie, Tomoyuki Honda, Yoshiyuki Suzuki, Yuki Kobayashi, Takuji Daito, Tatsuo Oshida, Kazuyoshi Ikuta, Patric Jern, Takashi Gojobori, John M. Coffin, Keizo Tomonaga
  • Journal Title: Nature 463 Pages: 84-87
  • Peer Reviewed
• [Journal Article] Low genetic diversities of rabies virus populations within different hosts in Brazil. (2010)
  • Author(s): Yuki Kobayashi, Yoshiyuki Suzuki, Takuya Itou, Adolorata A.B. Carvalho, Elenice M.S. Cunha, Fumio H. Ito, Takashi Gojobori, Takeo Sakai
  • Journal Title: Infection, Genetics and Evolution 10 Pages: 278-283
  • Peer Reviewed
• [Journal Article] A phylogenetic approach to detecting reassortments in viruses with segmented genomes. (2010)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Gene 464 Pages: 11-16
  • Peer Reviewed
• [Journal Article] The neutral theory of molecular evolution in the genomic era. (2010)
  • Author(s): Masatoshi Nei
  • Journal Title: Annual Review of Genomics and Human Genetics Volume: 11 Pages: 265-289
  • Peer Reviewed
• [Journal Article] Statistical methods for detecting natural selection from genomic data. (2010)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Genes & Genetic Systems Volume: 85 Pages: 359-376
  • NAID: 10029515818
  • Peer Reviewed
• [Journal Article] Is positive selection responsible for the evolution of a duplicate UV-sensitive opsin gene in Heliconius butterflies? (2010)
  • Author(s): Masafumi Nozawa
  • Journal Title: Proceedings of the National Academy of Sciencesof the United States of America Volume: 107
  • Peer Reviewed
• [Journal Article] Endogenous non-retroviral RNA virus elements in mammalian genomes. (2010)
  • Author(s): Masayuki Horie
  • Journal Title: Nature Volume: 463 Pages: 84-87
  • Peer Reviewed
• [Journal Article] Low genetic diversities of rabies virus populations within different hosts in Brazil (2010)
  • Author(s): Yuki Kobayashi
  • Journal Title: Infection, Genetics and Evolution Volume: 10 Pages: 278-283
  • Peer Reviewed
• [Journal Article] Genetic evidence supports linguistic affinity of Mlabri -a hunter-gatherer group in Thailand. (2010)
  • Author(s): Shuhua Xu
  • Journal Title: BMC Genetics Volume: 11 Pages: 18-18
  • Peer Reviewed
• [Journal Article] Genomic events contributing to high prevalence of amantadine-resistant influenza A/H3N2. (2010)
  • Author(s): Hassan Zaraket
  • Journal Title: Antiviral Therapy Volume: 15 Pages: 307-319
  • Peer Reviewed
• [Journal Article] A phylogenetic approach to detecting reassortments in viruses with segmented genomes. (2010)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Gene Volume: 464 Pages: 11-16
  • Peer Reviewed
• [Journal Article] problems with Bayesian methods of detecting positive selection at the DNA sequence level. (2009)
  • Author(s): Masafumi Nozawa, Yoshiyuki Suzuki, Masatoshi Nei : Response to Yang, et al.
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America 106
  • Peer Reviewed
• [Journal Article] Reliabilities of identifying positive selection by the branch-site and the site-prediction methods. (2009)
  • Author(s): Masafumi Nozawa, Yoshiyuki Suzuki, Masatoshi Nei
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America 106 Pages: 6700-6705
  • Peer Reviewed
• [Journal Article] Methods for incorporating the hypermutability of CpG dinucleotides in detecting natural selection operating at the amino acid sequence level. (2009)
  • Author(s): Yoshiyuki Suzuki, Takashi Gojobori, Sudhir Kumar
  • Journal Title: Molecular Biology and Evolution 26 Pages: 2275-2284
  • Peer Reviewed
• [Journal Article] Mapping human genetic diversity in Asia. (2009)
  • Author(s): The HUGO Pan-Asian SNP Consortium
  • Journal Title: Science 326 Pages: 1541-1545
  • Peer Reviewed
• [Journal Article] The evolutionary study of small RNA-directed gene silencing pathways by investigating RNase III enzymes. (2009)
  • Author(s): Lihua Jin, Kirill Kryukov, Yoshiyuki Suzuki, Tadashi Imanishi, Kazuho Ikeo, Takashi Gojobori
  • Journal Title: Gene 435 Pages: 1-8
  • Peer Reviewed
• [Journal Article] The evolutionary study of small RNA-directed gene silencing pathways by investigating RNase III enzymes (2009)
  • Author(s): Lihua Jin
  • Journal Title: Gene 435 Pages: 1-8
  • Peer Reviewed
• [Journal Article] Masatoshi Nei : Reliabilities of identifying positive selection by the branch-site and the site-prediction methods (2009)
  • Author(s): Masafumi Nozawa
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America 106 Pages: 6700-6795
  • Peer Reviewed
• [Journal Article] Methods for incorporating the hypermutability of CpG dinucleotides in detecting natural selection operatine at the amino acid sequence level (2009)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Molecular Biology and Evolution 26 Pages: 2275-2284
  • Peer Reviewed
• [Journal Article] Mapping human genetic diversity in Asia (2009)
  • Author(s): The HUGO Pan-Asian SNP Consortium
  • Journal Title: Science 326 Pages: 1541-1545
  • Peer Reviewed
• [Journal Article] Response to Yang, et al.: problems with Bayesian methods of detecting positive selection at the DNA sequence level (2009)
  • Author(s): Masafumi Nozawa
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America 106
  • Peer Reviewed
• [Journal Article] Evola : ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees. (2008)
  • Author(s): Akihiro Matsuya, et al.
  • Journal Title: Nucleic Acids Research 36
  • Peer Reviewed
• [Journal Article] Information Integration Project and H-Invitational 2 Consortium : The H-invitational database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (2008)
  • Author(s): Genome
  • Journal Title: Nucleic Acids Research 36
  • Peer Reviewed
• [Journal Article] Phylogenetic window analysis for detecting chronological changes in natural selection. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Open Evolution Journal 2 Pages: 13-30
  • Peer Reviewed
• [Journal Article] False-positive results obtained from the branch-test of positive selection. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Genes & Genetic Systems 83 Pages: 331-338
  • Peer Reviewed
• [Journal Article] The evolutionary relationship between gene duplication and alternative splicing. (2008)
  • Author(s): Lihua Jin, Kirill Kryukov, Jose C. Clemente, Tomoyoshi Komiyama, Yoshiyuki Suzuki, Tadashi Imanishi, Kazuho Ikeo, Takashi Gojobori
  • Journal Title: Gene 427 Pages: 19-31
  • Peer Reviewed
• [Journal Article] Positive selection operates continuously on hemagglutinin during evolution of H3N2 human influenza A virus. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Journal Title: Gene 427 Pages: 111-116
  • Peer Reviewed
• [Journal Article] Evola : ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees. (2008)
  • Author(s): Akihiro Matsuya
  • Journal Title: Nucleic Acids Research 36
  • Peer Reviewed
• [Journal Article] The H-invitational database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (2008)
  • Author(s): Chisato Yamasaki
  • Journal Title: Nucleic Acids Research 36
  • Peer Reviewed
• [Journal Article] The evolutionary relationship between gene duplication and alternative splicing. (2008)
  • Author(s): Lihua Jin
  • Journal Title: Gene 427 Pages: 19-31
  • Peer Reviewed
• [Presentation] Endogenous Borna-like N elements (2011)
  • Author(s): 鈴木善幸
  • Organizer: 第9回生物多様性研究センター勉強会
  • Place of Presentation: 名古屋市立大学
  • Year and Date: 2011-03-17
• [Presentation] Molecular evolution of influenza viruses (2011)
  • Author(s): 鈴木善幸
  • Organizer: 新潟大学セミナー
  • Place of Presentation: 新潟大学
  • Year and Date: 2011-01-28
• [Presentation] 遺伝子組み換え検出法の開発 (2011)
  • Author(s): 鈴木善幸
  • Organizer: 食品中の病原ウイルスのリスク管理に関する研究
  • Place of Presentation: 国立医薬品食品衛生研究所
  • Year and Date: 2011-01-26
• [Presentation] CpG高突然変異率を考慮したアミノ酸配列レベルに働く自然選択圧検出法の開発 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第82回日本遺伝学会大会
  • Place of Presentation: 札幌
  • Year and Date: 2010-09-30
• [Presentation] CpG高突然変異率を考慮したアミノ酸配列レベルに働く自然選択圧検出法の開発 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第82回日本遺伝学会大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2010-09-30
• [Presentation] インフルエンザウイルスの分子進化 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第20回日本数理生物学会大会シンポジウム「感染症と数理生物学」
  • Place of Presentation: 札幌
  • Year and Date: 2010-09-27
• [Presentation] インフルエンザウイルスの分子進化 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第20回日本数理生物学会大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2010-09-27
• [Presentation] ゲノム進化学の新展開 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第12回日本進化学会大会ワークショップ「ゲノム進化学の新展開」
  • Place of Presentation: 大岡山
  • Year and Date: 2010-08-13
• [Presentation] ゲノム進化学の新展開 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第12回日本進化学会大会
  • Place of Presentation: 東京工業大学
  • Year and Date: 2010-08-13
• [Presentation] ウイルスと遺伝学について (2010)
  • Author(s): 鈴木善幸
  • Organizer: 平成22年度三島商工会議所医看工連携・ミシマ定時会員総会記念講演会
  • Place of Presentation: 三島
  • Year and Date: 2010-07-12
• [Presentation] Natural selection operating on the influenza virus genome. (2010)
  • Author(s): 鈴木善幸
  • Organizer: 第24回インフルエンザ研究者交流の会シンポジウム
  • Place of Presentation: 軽井沢
  • Year and Date: 2010-07-11
• [Presentation] ノロウイルス遺伝子型分別システムの開発 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 食品中の病原ウイルスのリスク管理に関する研究
  • Place of Presentation: 国立医薬品食品衛生研究所
  • Year and Date: 2010-06-30
• [Presentation] 私の研究のこれまでとこれから、教育に対する考え方 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 名古屋市立大学セミナー
  • Place of Presentation: 名古屋市立大学
  • Year and Date: 2010-06-17
• [Presentation] ゲノム進化学の新展開.国立遺伝学研究所研究会「大規模データの表現方法:次世代ゲノムシーケンサーからの効率的なデータ活用に向けて」 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 産業技術総合研究所臨海副都心センター
  • Place of Presentation: 青海
  • Year and Date: 2010-03-29
• [Presentation] ゲノム進化学の新展開 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 国立遺伝学研究所研究会「大規模データの表現方法:次世代ゲノムシーケンサーからの効率的なデータ活用に向けて」
  • Place of Presentation: 産業技術総合研究所臨海副都心センター
  • Year and Date: 2010-03-29
• [Presentation] Positive Darwinian evolution and purifying evolution in RNA viruses. (2010)
  • Author(s): 鈴木善幸
  • Organizer: International Rotavirus Workshop in Nagasaki
  • Place of Presentation: Nagasaki, Japan
  • Year and Date: 2010-03-26
• [Presentation] Positive Darwinian evolution and purifying evolution in RNA viruses (2010)
  • Author(s): 鈴木善幸
  • Organizer: International Rotavirus Workshop in Nagasaki
  • Place of Presentation: Nagasaki University
  • Year and Date: 2010-03-26
• [Presentation] Methods for detecting natural selection operating at the amino acid sequence level (2010)
  • Author(s): 鈴木善幸
  • Organizer: 名古屋市立大学システム自然科学研究科セミナー
  • Place of Presentation: 名古屋市立大学
  • Year and Date: 2010-02-23
• [Presentation] 哺乳類ゲノム内在性非レトロRNAウイルス遺伝子の発見 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 国立遺伝学研究所研究会「次世代シーケンサーを活用したゲノム多様性の研究」
  • Place of Presentation: 三島
  • Year and Date: 2010-01-14
• [Presentation] 哺乳類ゲノム内在性非レトロRNAウイルス遺伝子の発見 (2010)
  • Author(s): 鈴木善幸
  • Organizer: 国立遺伝学研究所研究会「次世代シーケンサーを活用したゲノム多様性の研究」
  • Place of Presentation: 国立遺伝学研究所
  • Year and Date: 2010-01-14
• [Presentation] Detection of natural selection in viral proteins (2009)
  • Author(s): 鈴木善幸
  • Organizer: Molecular Epidemiology Seminar
  • Place of Presentation: Nagasaki University
  • Year and Date: 2009-12-14
• [Presentation] Introduction to bioinformatics of hepatitis viruses. Special Hands-on Seminar "How to Master Bioinformatics of Hepatitis Viruses Using International Databases" (2009)
  • Author(s): 鈴木善幸
  • Organizer: International Medical Center of Japan
  • Place of Presentation: Shinjuku, Japan
  • Year and Date: 2009-11-23
• [Presentation] How to detect natural selection. Special Hands-on Seminar "How to Master Bioinformatics of Hepatitis Viruses Using International Databases" (2009)
  • Author(s): 鈴木善幸
  • Organizer: International Medical Center of Japan
  • Place of Presentation: Shinjuku, Japan
  • Year and Date: 2009-11-23
• [Presentation] Introduction to bioinformatics of hepatitis viruses (2009)
  • Author(s): 鈴木善幸
  • Organizer: Special Hands-on Seminar "How to Master Bioinfonnatics of Hepatitis Viruses Using International Databases"
  • Place of Presentation: International Medical Center of Japan
  • Year and Date: 2009-11-23
• [Presentation] How to detect natural selection (2009)
  • Author(s): 鈴木善幸
  • Organizer: Special Hands-on Seminar "How to Master Bioinformatics of Hepatitis Viruses Using International Databases"
  • Place of Presentation: International Medical Center of Japan
  • Year and Date: 2009-11-23
• [Presentation] 分子進化遺伝学の基礎 (2009)
  • Author(s): 鈴木善幸
  • Organizer: ウイルス性下痢症研究会第21回学術集会、国立感染症研究所戸山庁舎
  • Place of Presentation: 新宿
  • Year and Date: 2009-10-24
• [Presentation] 分子進化遺伝学の基礎 (2009)
  • Author(s): 鈴木善幸
  • Organizer: ウイルス性下痢症研究会第21回学術集会
  • Place of Presentation: 国立感染症研究所戸山庁舎
  • Year and Date: 2009-10-24
• [Presentation] Methods for incorporating the hypermutability of CpG dinucleotides in detecting natural selection operating at the amino acid sequence level (2009)
  • Author(s): 鈴木善幸
  • Organizer: The 967th National Institute of Genetics Colloquium
  • Place of Presentation: National Institute of Genetics
  • Year and Date: 2009-10-16
• [Presentation] ヒトインフルエンザA型ウイルス(H3N2亜型)ヘマグルチニンには正の自然選択が連続的に働いている (2009)
  • Author(s): 鈴木善幸
  • Organizer: 第81回日本遺伝学会大会
  • Place of Presentation: 松本
  • Year and Date: 2009-09-18
• [Presentation] ヒトインフルエンザA型ウイルス(H3N2亜型)ヘマグルチニンには正の自然選択が連続的に働いている (2009)
  • Author(s): 鈴木善幸
  • Organizer: 第81回日本遺伝学会大会
  • Place of Presentation: 信州大学
  • Year and Date: 2009-09-18
• [Presentation] Reliabilities of identifying positive selection by the branch-site and the site-prediction methods (2009)
  • Author(s): 鈴木善幸
  • Organizer: The 4th NIG Poster Workshop
  • Place of Presentation: National Institute of Genetics
  • Year and Date: 2009-05-21
• [Presentation] Development of reliable methods for detecting natural selection operating at the amino acid sequence level (2009)
  • Author(s): 鈴木善幸
  • Organizer: 京都大学ゲノム医学センターセミナー
  • Place of Presentation: 京都大学
  • Year and Date: 2009-04-29
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Organizer: Center for Information Biology Internal Seminar
  • Place of Presentation: Ochanomizu University
  • Year and Date: 2008-12-18
• [Presentation] False-positive results obtained from the branch-site test of positive selection. Symposium "Darwinian selection identified from comparative genomics" (2008)
  • Author(s): 鈴木善幸
  • Organizer: Joint Annual Meeting of the Molecular Biology Society of Japan and the Japanese Biochemical Society, 2008 (The 31st Annual Meeting of the Molecular Biology Society of Japan and The 81st Annual Meeting of the Japanese Biochemical Society)
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2008-12-10
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Organizer: 第31回日本分子生物学会大会
  • Place of Presentation: Kobe Port Island
  • Year and Date: 2008-12-10
• [Presentation] DDBJの紹介 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 製薬協情報技術検討会DDBJ見学会
  • Place of Presentation: 国立遺伝学研究所
  • Year and Date: 2008-11-28
• [Presentation] branch-siteテストによる正の自然選択検出における偽陽性率 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第80回日本遺伝学会大会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-09-05
• [Presentation] branch-siteテストによる正の自然選択検出における偽陽性率 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第80回日本遺伝学会大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2008-09-05
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第10回日本進化学会大会ワークショップ「ゲノム解析から見える自然選択」
  • Place of Presentation: 駒場
  • Year and Date: 2008-08-23
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第10回日本進化学会大会ワークショップ「ゲノム解析から見える自然選択」
  • Place of Presentation: 東京大学
  • Year and Date: 2008-08-23
• [Presentation] False-positive resultsobtained from the branch-site test ofpositive selection. (2008)
  • Author(s): 鈴木善幸
  • Organizer: 国立遺伝学研究所研究会「中立進化論の現在」
  • Place of Presentation: 三島
  • Year and Date: 2008-07-28
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): 鈴木善幸
  • Organizer: 国立遺伝学研究所研究会「中立進化論の現在」
  • Place of Presentation: 国立遺伝学研究所
  • Year and Date: 2008-07-28
• [Presentation] データベース検索実習2 FASTA、BLASTの使い方 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第19回DDBJing講習会
  • Place of Presentation: 国立遺伝学研究所
  • Year and Date: 2008-06-19
• [Presentation] False-positive results obtained from the branch-site test of positive selection. (2008)
  • Author(s): Yoshiyuki Suzuki
  • Organizer: The 924th National Institute of Genetics Colloquium
  • Place of Presentation: National Institute of Genetics
  • Year and Date: 2008-05-30
• [Presentation] インフルエンザウイルス蛋白質に働く自然選択圧の検出 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第22回インフルエンザ研究者交流の会シンポジウム
  • Place of Presentation: 白金台
  • Year and Date: 2008-05-19
• [Presentation] インフルエンザウイルス蛋白質に働く自然選択圧の検出 (2008)
  • Author(s): 鈴木善幸
  • Organizer: 第22回インフルエンザ研究者交流の会シンポジウム
  • Place of Presentation: 東京大学医科学研究所
  • Year and Date: 2008-05-19